product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-PLCγ1 (Tyr783) Antibody
catalog :
2821
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
antigen modification :
phosphorylated
reactivity :
hamsters, human, mouse, rat
application :
western blot, immunoprecipitation, flow cytometry
citations: 21
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:1000; loading ...; fig 5i
Herranz C, Mateo F, Baiges A, Ruiz de Garibay G, Junza A, Johnson S, et al. Histamine signaling and metabolism identify potential biomarkers and therapies for lymphangioleiomyomatosis. EMBO Mol Med. 2021;13:e13929 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 6e
Shang P, Stepicheva N, Teel K, McCauley A, Fitting C, Hose S, et al. βA3/A1-crystallin regulates apical polarity and EGFR endocytosis in retinal pigmented epithelial cells. Commun Biol. 2021;4:850 pubmed publisher
  • western blot; mouse; loading ...; fig 5e
Abu Odeh M, Zhang Y, Reilly S, Ebadat N, Keinan O, Valentine J, et al. FGF21 promotes thermogenic gene expression as an autocrine factor in adipocytes. Cell Rep. 2021;35:109331 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig s10a
Cook S, Comrie W, Poli M, Similuk M, Oler A, Faruqi A, et al. HEM1 deficiency disrupts mTORC2 and F-actin control in inherited immunodysregulatory disease. Science. 2020;369:202-207 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig ev1c
Buhl E, Djudjaj S, Klinkhammer B, Ermert K, Puelles V, Lindenmeyer M, et al. Dysregulated mesenchymal PDGFR-β drives kidney fibrosis. EMBO Mol Med. 2020;12:e11021 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 4c
Liu T, Han S, Dai Q, Zheng J, Liu C, Li S, et al. IL-17A-Mediated Excessive Autophagy Aggravated Neuronal Ischemic Injuries via Src-PP2B-mTOR Pathway. Front Immunol. 2019;10:2952 pubmed publisher
  • western blot; hamsters; 1:2000; loading ...; fig 8a
Vrijens P, Noppen S, Boogaerts T, Vanstreels E, Ronca R, Chiodelli P, et al. Influenza virus entry via the GM3 ganglioside-mediated platelet-derived growth factor receptor β signalling pathway. J Gen Virol. 2019;100:583-601 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 3a
Yang G, Zhao Z, Qin T, Wang D, Chen L, Xiang R, et al. TNFSF15 inhibits VEGF-stimulated vascular hyperpermeability by inducing VEGFR2 dephosphorylation. FASEB J. 2017;31:2001-2012 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig e3
Mueller A, van Velthoven C, Fukumoto K, Cheung T, Rando T. Intronic polyadenylation of PDGFR? in resident stem cells attenuates muscle fibrosis. Nature. 2016;540:276-279 pubmed publisher
  • western blot; human; 1:1000; fig st1
Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed publisher
  • western blot; human; fig 5b
Egholm C, Khammy M, Dalsgaard T, Mazur A, Tritsaris K, Hansen A, et al. GLP-1 inhibits VEGFA-mediated signaling in isolated human endothelial cells and VEGFA-induced dilation of rat mesenteric arteries. Am J Physiol Heart Circ Physiol. 2016;311:H1214-H1224 pubmed publisher
  • western blot; rat; 1:1000; fig 3
Gao G, He J, Nong L, Xie H, Huang Y, Xu N, et al. Periodic mechanical stress induces the extracellular matrix expression and migration of rat nucleus pulposus cells by upregulating the expression of intergrin ?1 and phosphorylation of downstream phospholipase C?1. Mol Med Rep. 2016;14:2457-64 pubmed publisher
  • western blot; human; 1:1000; fig 6
  • western blot; mouse; 1:1000; fig 8
Blas Rus N, Bustos Morán E, Perez de Castro I, de Carcer G, Borroto A, Camafeita E, et al. Aurora A drives early signalling and vesicle dynamics during T-cell activation. Nat Commun. 2016;7:11389 pubmed publisher
  • western blot; human; loading ...; fig 7
Rorsman C, Tsioumpekou M, Heldin C, Lennartsson J. The Ubiquitin Ligases c-Cbl and Cbl-b Negatively Regulate Platelet-derived Growth Factor (PDGF) BB-induced Chemotaxis by Affecting PDGF Receptor β (PDGFRβ) Internalization and Signaling. J Biol Chem. 2016;291:11608-18 pubmed publisher
  • western blot; human; fig 2
Ardini E, Menichincheri M, Banfi P, Bosotti R, De Ponti C, Pulci R, et al. Entrectinib, a Pan-TRK, ROS1, and ALK Inhibitor with Activity in Multiple Molecularly Defined Cancer Indications. Mol Cancer Ther. 2016;15:628-39 pubmed publisher
  • western blot; human; fig 2
Wang J, Goetsch L, Tucker L, Zhang Q, Gonzalez A, Vaidya K, et al. Anti-c-Met monoclonal antibody ABT-700 breaks oncogene addiction in tumors with MET amplification. BMC Cancer. 2016;16:105 pubmed publisher
  • western blot; mouse; fig 1
Vivar O, Masi G, Carpier J, Magalhaes J, Galgano D, Pazour G, et al. IFT20 controls LAT recruitment to the immune synapse and T-cell activation in vivo. Proc Natl Acad Sci U S A. 2016;113:386-91 pubmed publisher
  • western blot; mouse; loading ...; fig 2c
Ishibashi T, Yaguchi A, Terada K, Ueno Yokohata H, Tomita O, Iijima K, et al. Ph-like ALL-related novel fusion kinase ATF7IP-PDGFRB exhibits high sensitivity to tyrosine kinase inhibitors in murine cells. Exp Hematol. 2016;44:177-88.e5 pubmed publisher
Coomans de Brachène A, Dif N, de Rocca Serra A, Bonnineau C, Velghe A, Larondelle Y, et al. PDGF-induced fibroblast growth requires monounsaturated fatty acid production by stearoyl-CoA desaturase. FEBS Open Bio. 2017;7:414-423 pubmed publisher
Yoo J, Yang J, Kim Y, Cho W, Ma J. Inhibitory Effect of Loranthus parasiticus on IgE-Mediated Allergic Responses in RBL-2H3 Cells. Mediators Inflamm. 2016;2016:8742562 pubmed
Keller B, Zaidman I, Yousefi O, Hershkovitz D, Stein J, Unger S, et al. Early onset combined immunodeficiency and autoimmunity in patients with loss-of-function mutation in LAT. J Exp Med. 2016;213:1185-99 pubmed publisher
product information
SKU :
2821S
Product-Name :
Phospho-PLCγ1 (Tyr783) Antibody
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H, M, R
Applications :
Flow cytometry
Product-Category :
Ca, cAMP and Lipid Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
155
Host :
Rabbit
Target :
PLCg1 (Tyr783) phosphate
Primary-Protein :
PLCG1
Alt-Names :
1-phosphatidyl-D-myo-inositol-4,5-bisphosphate,1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1,1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1,NCKAP3,PLC-148,PLC-II,PLC-gamma-1,PLC1,PLC148,PLCG1,PLCgamma1,Phosphoinositide phospholipase C-gamma-1,Phospholipase C-II,Phospholipase C-gamma-1,inositoltrisphosphohydrolase,monophosphatidylinositol phosphodiesterase,phosphatidylinositol phospholipase C,phosphoinositidase C,phosphoinositide phospholipase C,phospholipase C, gamma 1,phospholipase C, gamma 1 (formerly subtype 148),phospholipase C-148,triphosphoinositide phosphodiesterase
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.