product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Bim Antibody
catalog :
2819S
quantity :
100 ul
price :
235 USD
clonality :
polyclonal
host :
rabbit
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation, flow cytometry
citations: 11
Published Application/Species/DilutionReference
  • western blot; mouse; fig 4
Wang E, Kawaoka S, Roe J, Shi J, Hohmann A, Xu Y, et al. The transcriptional cofactor TRIM33 prevents apoptosis in B lymphoblastic leukemia by deactivating a single enhancer. elife. 2015;4:e06377 pubmed publisher
  • western blot; human; 1:500
Rizvi S, Mertens J, Bronk S, Hirsova P, Dai H, Roberts L, et al. Platelet-derived growth factor primes cancer-associated fibroblasts for apoptosis. J Biol Chem. 2014;289:22835-49 pubmed publisher
  • western blot; human
Cazanave S, Wang X, Zhou H, Rahmani M, Grant S, Durrant D, et al. Degradation of Keap1 activates BH3-only proteins Bim and PUMA during hepatocyte lipoapoptosis. Cell Death Differ. 2014;21:1303-12 pubmed publisher
Wu W, Wu Q, Hong X, Zhou L, Zhang J, You L, et al. Catechol-O-methyltransferase, a new target for pancreatic cancer therapy. Cancer Sci. 2015;106:576-83 pubmed publisher
Denoyelle C, Lambert B, Meryet-Figuiere M, Vigneron N, Brotin E, Lecerf C, et al. miR-491-5p-induced apoptosis in ovarian carcinoma depends on the direct inhibition of both BCL-XL and EGFR leading to BIM activation. Cell Death Dis. 2014;5:e1445 pubmed publisher
Tagoug I, Sauty De Chalon A, Dumontet C. Inhibition of IGF-1 signalling enhances the apoptotic effect of AS602868, an IKK2 inhibitor, in multiple myeloma cell lines. PLoS ONE. 2011;6:e22641 pubmed publisher
Weisberg E, Ray A, Nelson E, Adamia S, Barrett R, Sattler M, et al. Reversible resistance induced by FLT3 inhibition: a novel resistance mechanism in mutant FLT3-expressing cells. PLoS ONE. 2011;6:e25351 pubmed publisher
Kurtulus S, Tripathi P, Moreno-Fernandez M, Sholl A, Katz J, Grimes H, et al. Bcl-2 allows effector and memory CD8+ T cells to tolerate higher expression of Bim. J Immunol. 2011;186:5729-37 pubmed publisher
Faber A, Corcoran R, Ebi H, Sequist L, Waltman B, Chung E, et al. BIM expression in treatment-naive cancers predicts responsiveness to kinase inhibitors. Cancer Discov. 2011;1:352-65 pubmed publisher
Choi P, van Riggelen J, Gentles A, Bachireddy P, Rakhra K, Adam S, et al. Lymphomas that recur after MYC suppression continue to exhibit oncogene addiction. Proc Natl Acad Sci U S A. 2011;108:17432-7 pubmed publisher
Widenmaier S, Ao Z, Kim S, Warnock G, McIntosh C. Suppression of p38 MAPK and JNK via Akt-mediated inhibition of apoptosis signal-regulating kinase 1 constitutes a core component of the beta-cell pro-survival effects of glucose-dependent insulinotropic polypeptide. J Biol Chem. 2009;284:30372-82 pubmed publisher
product information
SKU :
2819S
Product-Name :
Bim Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, (Mk)
Applications :
Flow cytometry
Product-Category :
Apoptosis
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
23, 15, 12
Host :
Rabbit
Target :
Bim
Primary-Protein :
Bim
Alt-Names :
B2L11,BAM,BCL2-like 11 (apoptosis facilitator),BCL2L11,BIM,BIM-alpha6,BIM-beta6,BIM-beta7,BOD,Bcl-2-like protein 11,Bcl2-L-11,Bcl2-interacting mediator of cell death,BimEL,BimL,bcl-2 interacting mediator of cell death,bcl-2 interacting protein Bim,bcl-2-related ovarian death agonist
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.