| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; human; fig 5c
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- western blot; human; loading ...; fig s2b
| Haikala H, Anttila J, Marques E, Raatikainen T, Ilander M, Hakanen H, et al. Pharmacological reactivation of MYC-dependent apoptosis induces susceptibility to anti-PD-1 immunotherapy. Nat Commun. 2019;10:620 pubmed publisher |
- western blot; human; loading ...; fig 3a
| Bogenberger J, Whatcott C, Hansen N, Delman D, Shi C, Kim W, et al. Combined venetoclax and alvocidib in acute myeloid leukemia. Oncotarget. 2017;8:107206-107222 pubmed publisher |
- western blot; human; loading ...; fig 1a
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- immunohistochemistry - paraffin section; human; 1:100; loading ...
- western blot; human; loading ...; fig 4d
| Kong P, Zhu X, Geng Q, Xia L, Sun X, Chen Y, et al. The microRNA-423-3p-Bim Axis Promotes Cancer Progression and Activates Oncogenic Autophagy in Gastric Cancer. Mol Ther. 2017;25:1027-1037 pubmed publisher |
- western blot; human; loading ...; fig 6c
| Mandl M, Zhang S, Ulrich M, Schmoeckel E, Mayr D, Vollmar A, et al. Inhibition of Cdk5 induces cell death of tumor-initiating cells. Br J Cancer. 2017;116:912-922 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 5a
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- western blot; human; loading ...; fig 5f
| Horn T, Ferretti S, Ebel N, Tam A, Ho S, Harbinski F, et al. High-Order Drug Combinations Are Required to Effectively Kill Colorectal Cancer Cells. Cancer Res. 2016;76:6950-6963 pubmed |
- western blot; human; 1:1000; loading ...; fig 1e
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- western blot; human; loading ...; fig 4a
| Zhao J, Niu X, Li X, Edwards H, Wang G, Wang Y, et al. Inhibition of CHK1 enhances cell death induced by the Bcl-2-selective inhibitor ABT-199 in acute myeloid leukemia cells. Oncotarget. 2016;7:34785-99 pubmed publisher |
- immunohistochemistry; mouse; 1:2000; fig s1b
- western blot; mouse; 1:2000; fig s1b
- western blot; human; 1:2000; loading ...; fig s1c
| Hornsveld M, Tenhagen M, van de Ven R, Smits A, van Triest M, van Amersfoort M, et al. Restraining FOXO3-dependent transcriptional BMF activation underpins tumour growth and metastasis of E-cadherin-negative breast cancer. Cell Death Differ. 2016;23:1483-92 pubmed publisher |
- western blot; human; fig s6
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- western blot; human; fig 2
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- western blot; human; 1:1000; loading ...; fig 2d
| Ko T, Chin H, Chuah C, Huang J, Ng K, Khaw S, et al. The BIM deletion polymorphism: A paradigm of a permissive interaction between germline and acquired TKI resistance factors in chronic myeloid leukemia. Oncotarget. 2016;7:2721-33 pubmed publisher |
- western blot; human; fig 2
| Hutchinson K, Johnson D, Johnson A, Sanchez V, Kuba M, Lu P, et al. ERBB activation modulates sensitivity to MEK1/2 inhibition in a subset of driver-negative melanoma. Oncotarget. 2015;6:22348-60 pubmed |
- western blot; human; fig s3
| Yang N, Gilman P, Mirzayans R, Sun X, Touret N, Weinfeld M, et al. Characterization of the apoptotic response induced by the cyanine dye D112: a potentially selective anti-cancer compound. PLoS ONE. 2015;10:e0125381 pubmed publisher |
- western blot; mouse; fig 4
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- western blot; human; 1:500
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| Machado A, Rodríguez Expósito E, Lopez M, Hernandez M. Phylogenetic analysis of the genus Laparocerus, with comments on colonisation and diversification in Macaronesia (Coleoptera, Curculionidae, Entiminae). Zookeys. 2017;:1-77 pubmed publisher |
| Rauzan M, Chuah C, Ko T, Ong S. The HDAC inhibitor SB939 overcomes resistance to BCR-ABL kinase Inhibitors conferred by the BIM deletion polymorphism in chronic myeloid leukemia. PLoS ONE. 2017;12:e0174107 pubmed publisher |
| Chen S, Zhou J, Cai Y, Zheng X, Xie S, Liao Y, et al. Discovery of BVDU as a promising Drug for autoimmune diseases Therapy by Dendritic-cell-based functional screening. Sci Rep. 2017;7:43820 pubmed publisher |
| Su H, Waldron R, Gong R, Ramanujan V, Pandol S, Lugea A. The Unfolded Protein Response Plays a Predominant Homeostatic Role in Response to Mitochondrial Stress in Pancreatic Stellate Cells. PLoS ONE. 2016;11:e0148999 pubmed publisher |
| Varadaraj A, Patel P, Serrao A, Bandyopadhay T, Lee N, Jazaeri A, et al. Epigenetic Regulation of GDF2 Suppresses Anoikis in Ovarian and Breast Epithelia. Neoplasia. 2015;17:826-38 pubmed publisher |
| Karachaliou N, Codony Servat J, Teixidó C, Pilotto S, Drozdowskyj A, Codony Servat C, et al. BIM and mTOR expression levels predict outcome to erlotinib in EGFR-mutant non-small-cell lung cancer. Sci Rep. 2015;5:17499 pubmed publisher |
| Phua Y, Chu J, Marrone A, Bodnar A, Sims Lucas S, Ho J. Renal stromal miRNAs are required for normal nephrogenesis and glomerular mesangial survival. Physiol Rep. 2015;3: pubmed publisher |
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| Denoyelle C, Lambert B, Meryet Figuière M, Vigneron N, Brotin E, Lecerf C, et al. miR-491-5p-induced apoptosis in ovarian carcinoma depends on the direct inhibition of both BCL-XL and EGFR leading to BIM activation. Cell Death Dis. 2014;5:e1445 pubmed publisher |
| Soh S, Lim J, Huang J, Jiang N, Yeoh A, Ong S. Multi-agent chemotherapy overcomes glucocorticoid resistance conferred by a BIM deletion polymorphism in pediatric acute lymphoblastic leukemia. PLoS ONE. 2014;9:e103435 pubmed publisher |
| Juan W, Roca X, Ong S. Identification of cis-acting elements and splicing factors involved in the regulation of BIM Pre-mRNA splicing. PLoS ONE. 2014;9:e95210 pubmed publisher |
| Pandey M, Gowda K, Doi K, Sharma A, Wang H, Amin S. Proteasomal degradation of Mcl-1 by maritoclax induces apoptosis and enhances the efficacy of ABT-737 in melanoma cells. PLoS ONE. 2013;8:e78570 pubmed publisher |
| Thompson R, Vardinogiannis I, Gilmore T. The sensitivity of diffuse large B-cell lymphoma cell lines to histone deacetylase inhibitor-induced apoptosis is modulated by BCL-2 family protein activity. PLoS ONE. 2013;8:e62822 pubmed publisher |
| Brennan G, Jimenez Mateos E, McKiernan R, Engel T, Tzivion G, Henshall D. Transgenic overexpression of 14-3-3 zeta protects hippocampus against endoplasmic reticulum stress and status epilepticus in vivo. PLoS ONE. 2013;8:e54491 pubmed publisher |
| Selimoglu Buet D, Gallais I, Denis N, Guillouf C, Moreau Gachelin F. Oncogenic kit triggers Shp2/Erk1/2 pathway to down-regulate the pro-apoptotic protein Bim and to promote apoptosis resistance in leukemic cells. PLoS ONE. 2012;7:e49052 pubmed publisher |
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