| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; human; loading ...; fig 1e
| Zuo J, Zhao M, Fan Z, Liu B, Wang Y, Li Y, et al. MicroRNA-153-3p regulates cell proliferation and cisplatin resistance via Nrf-2 in esophageal squamous cell carcinoma. Thorac Cancer. 2020;11:738-747 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 3e
| Shen S, Dean D, Yu Z, Hornicek F, Kan Q, Duan Z. Aberrant CDK9 expression within chordoma tissues and the therapeutic potential of a selective CDK9 inhibitor LDC000067. J Cancer. 2020;11:132-141 pubmed publisher |
- immunocytochemistry; mouse; 1:500; loading ...; fig s1a
| Akera T, Trimm E, Lampson M. Molecular Strategies of Meiotic Cheating by Selfish Centromeres. Cell. 2019;178:1132-1144.e10 pubmed publisher |
- western blot; human; 1:2000; loading ...; fig 7e
| Roy N, Monisha J, Padmavathi G, Lalhruaitluanga H, Kumar N, Singh A, et al. Isoform-Specific Role of Akt in Oral Squamous Cell Carcinoma. Biomolecules. 2019;9: pubmed publisher |
- western blot; human; 1:1000; loading ...; fig s2b
| Wang H, Huang F, Zhang Z, Wang P, Luo Y, Li H, et al. Feedback Activation of SGK3 and AKT Contributes to Rapamycin Resistance by Reactivating mTORC1/4EBP1 Axis via TSC2 in Breast Cancer. Int J Biol Sci. 2019;15:929-941 pubmed publisher |
- mass cytometry; human; loading ...; fig 3a
| Wagner J, Rapsomaniki M, Chevrier S, Anzeneder T, Langwieder C, Dykgers A, et al. A Single-Cell Atlas of the Tumor and Immune Ecosystem of Human Breast Cancer. Cell. 2019;177:1330-1345.e18 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; loading ...; fig 2e
| Bishnupuri K, Alvarado D, Khouri A, Shabsovich M, Chen B, Dieckgraefe B, et al. IDO1 and kynurenine pathway metabolites activate PI3K-Akt signaling in the neoplastic colon epithelium to promote cancer cell proliferation and inhibit apoptosis. Cancer Res. 2019;: pubmed publisher |
- western blot; human; loading ...; fig 2b
| Sahu U, Choudhury A, Parvez S, Biswas S, Kar S. Induction of intestinal stemness and tumorigenicity by aberrant internalization of commensal non-pathogenic E. coli. Cell Death Dis. 2017;8:e2667 pubmed publisher |
- western blot; mouse; fig 2a
- western blot; human; loading ...; fig 4a
| CAROMILE L, Dortche K, Rahman M, Grant C, Stoddard C, Ferrer F, et al. PSMA redirects cell survival signaling from the MAPK to the PI3K-AKT pathways to promote the progression of prostate cancer. Sci Signal. 2017;10: pubmed publisher |
- immunohistochemistry; mouse; loading ...; fig 5a
| Yamada M, Egli D. Genome Transfer Prevents Fragmentation and Restores Developmental Potential of Developmentally Compromised Postovulatory Aged Mouse Oocytes. Stem Cell Reports. 2017;8:576-588 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 3a
| Cai L, Wang H, Yang Q. CRKL overexpression promotes cell proliferation and inhibits apoptosis in endometrial carcinoma. Oncol Lett. 2017;13:51-56 pubmed publisher |
- western blot; human; loading ...; fig 5a
| Martínez Castillo M, Bonilla Moreno R, Alemán Lazarini L, Meraz Rios M, Orozco L, Cedillo Barron L, et al. A Subpopulation of the K562 Cells Are Killed by Curcumin Treatment after G2/M Arrest and Mitotic Catastrophe. PLoS ONE. 2016;11:e0165971 pubmed publisher |
- western blot; human; loading ...; fig 5a
| Lu W, Shi J, Zhang J, Lv Z, Guo F, Huang H, et al. CXCL12/CXCR4 Axis Regulates Aggrecanase Activation and Cartilage Degradation in a Post-Traumatic Osteoarthritis Rat Model. Int J Mol Sci. 2016;17: pubmed |
- western blot; human; loading ...; fig s4b
| Klingbeil O, Lesche R, Gelato K, Haendler B, Lejeune P. Inhibition of BET bromodomain-dependent XIAP and FLIP expression sensitizes KRAS-mutated NSCLC to pro-apoptotic agents. Cell Death Dis. 2016;7:e2365 pubmed publisher |
- immunocytochemistry; mouse; 1:500; loading ...; fig s4
| Balboula A, Nguyen A, Gentilello A, Quartuccio S, Drutovic D, Solc P, et al. Haspin kinase regulates microtubule-organizing center clustering and stability through Aurora kinase C in mouse oocytes. J Cell Sci. 2016;129:3648-3660 pubmed |
- immunohistochemistry; human; fig 2
| Malherbe J, Fuller K, Mirzai B, Kavanagh S, So C, Ip H, et al. Dysregulation of the intrinsic apoptotic pathway mediates megakaryocytic hyperplasia in myeloproliferative neoplasms. J Clin Pathol. 2016;: pubmed publisher |
- western blot; human; fig 5
| Lee S, Jeong A, Park J, Han S, Jang C, Kim K, et al. IK-guided PP2A suppresses Aurora B activity in the interphase of tumor cells. Cell Mol Life Sci. 2016;73:3375-86 pubmed publisher |
- western blot; human; fig 4
| Shukla S, Sinha S, Khan S, Kumar S, Singh K, Mitra K, et al. Cucurbitacin B inhibits the stemness and metastatic abilities of NSCLC via downregulation of canonical Wnt/β-catenin signaling axis. Sci Rep. 2016;6:21860 pubmed publisher |
- immunohistochemistry - frozen section; mouse; fig 5
| Passer D, van de Vrugt A, Atmanli A, Domian I. Atypical Protein Kinase C-Dependent Polarized Cell Division Is Required for Myocardial Trabeculation. Cell Rep. 2016;14:1662-1672 pubmed publisher |
- western blot; human; loading ...; fig 7b
| Ghosh S, Shinogle H, Galeva N, Dobrowsky R, Blagg B. Endoplasmic Reticulum-resident Heat Shock Protein 90 (HSP90) Isoform Glucose-regulated Protein 94 (GRP94) Regulates Cell Polarity and Cancer Cell Migration by Affecting Intracellular Transport. J Biol Chem. 2016;291:8309-23 pubmed publisher |
- immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 7c
- western blot; human; 1:1000; loading ...; fig 3a
| Park K, Yun H, Quang T, Oh H, Lee D, Auh Q, et al. 4-Methoxydalbergione suppresses growth and induces apoptosis in human osteosarcoma cells in vitro and in vivo xenograft model through down-regulation of the JAK2/STAT3 pathway. Oncotarget. 2016;7:6960-71 pubmed publisher |
- western blot; human; fig 5
| Huang Y, Chen Y, Lai Y, Cheng C, Lin T, Su Y, et al. Resveratrol alleviates the cytotoxicity induced by the radiocontrast agent, ioxitalamate, by reducing the production of reactive oxygen species in HK-2 human renal proximal tubule epithelial cells in vitro. Int J Mol Med. 2016;37:83-91 pubmed publisher |
- western blot; human; 1:1000; fig 5
| Wang B, Ma A, Zhang L, Jin W, Qian Y, Xu G, et al. POH1 deubiquitylates and stabilizes E2F1 to promote tumour formation. Nat Commun. 2015;6:8704 pubmed publisher |
- western blot; human; 1:1000; fig s3
| Lauková J, KozubÃk A, Hofmanová J, Nekvindová J, Sova P, Moyer M, et al. Loss of PTEN Facilitates Rosiglitazone-Mediated Enhancement of Platinum(IV) Complex LA-12-Induced Apoptosis in Colon Cancer Cells. PLoS ONE. 2015;10:e0141020 pubmed publisher |
- western blot; human; 1:1000; fig 3b
| Lim T, Lee I, Kim J, Kang W. Synergistic Effect of Simvastatin Plus Radiation in Gastric Cancer and Colorectal Cancer: Implications of BIRC5 and Connective Tissue Growth Factor. Int J Radiat Oncol Biol Phys. 2015;93:316-25 pubmed publisher |
- western blot; human; fig 3
| Wang J, Ma L, Tang X, Zhang X, Qiao Y, Shi Y, et al. Doxorubicin induces apoptosis by targeting Madcam1 and AKT and inhibiting protein translation initiation in hepatocellular carcinoma cells. Oncotarget. 2015;6:24075-91 pubmed |
- immunocytochemistry; mouse; 1:400; fig 3
- immunohistochemistry; mouse; 1:400; fig 6
| Tsuneki M, Hardee S, Michaud M, Morotti R, Lavik E, Madri J. A hydrogel-endothelial cell implant mimics infantile hemangioma: modulation by survivin and the Hippo pathway. Lab Invest. 2015;95:765-80 pubmed publisher |
- western blot; human; 1:1000; fig 2e
| Sadowski S, Boufraqech M, Zhang L, Mehta A, Kapur P, Zhang Y, et al. Torin2 targets dysregulated pathways in anaplastic thyroid cancer and inhibits tumor growth and metastasis. Oncotarget. 2015;6:18038-49 pubmed |
- immunocytochemistry; mouse; 1:500; fig 5
| Balboula A, Stein P, Schultz R, Schindler K. RBBP4 regulates histone deacetylation and bipolar spindle assembly during oocyte maturation in the mouse. Biol Reprod. 2015;92:105 pubmed publisher |
- western blot; human; loading ...; fig 1c
| Ulasov I, Shah N, Kaverina N, Lee H, Lin B, Lieber A, et al. Tamoxifen improves cytopathic effect of oncolytic adenovirus in primary glioblastoma cells mediated through autophagy. Oncotarget. 2015;6:3977-87 pubmed |
| Kim S, Nam S, Friedman M. The Tomato Glycoalkaloid α-Tomatine Induces Caspase-Independent Cell Death in Mouse Colon Cancer CT-26 Cells and Transplanted Tumors in Mice. J Agric Food Chem. 2015;63:1142-1150 pubmed publisher |
- immunohistochemistry; human; fig 7
- western blot; human; fig 1
| Blanchard Z, Paul B, Craft B, ElShamy W. BRCA1-IRIS inactivation overcomes paclitaxel resistance in triple negative breast cancers. Breast Cancer Res. 2015;17:5 pubmed publisher |
- western blot; human; loading ...; fig 3e
| Alayev A, Berger S, Kramer M, Schwartz N, Holz M. The combination of rapamycin and resveratrol blocks autophagy and induces apoptosis in breast cancer cells. J Cell Biochem. 2015;116:450-7 pubmed publisher |
- immunocytochemistry; mouse; 1:500; fig 5
| Nguyen A, Gentilello A, Balboula A, Shrivastava V, Ohring J, Schindler K. Phosphorylation of threonine 3 on histone H3 by haspin kinase is required for meiosis I in mouse oocytes. J Cell Sci. 2014;127:5066-78 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; loading ...; fig 1c
- western blot; mouse; loading ...; fig 1b
| Brun S, Markant S, Esparza L, Garcia G, Terry D, Huang J, et al. Survivin as a therapeutic target in Sonic hedgehog-driven medulloblastoma. Oncogene. 2015;34:3770-9 pubmed publisher |
- immunohistochemistry - paraffin section; human; 1:50
- western blot; human; 1:500
| Luk S, Xue H, Cheng H, Lin D, Gout P, Fazli L, et al. The BIRC6 gene as a novel target for therapy of prostate cancer: dual targeting of inhibitors of apoptosis. Oncotarget. 2014;5:6896-908 pubmed |
- western blot; human; 1:1000
| Althoff K, Lindner S, Odersky A, Mestdagh P, Beckers A, Karczewski S, et al. miR-542-3p exerts tumor suppressive functions in neuroblastoma by downregulating Survivin. Int J Cancer. 2015;136:1308-20 pubmed publisher |
| Herod M, Salim O, Skilton R, Prince C, Ward V, Lambden P, et al. Expression of the murine norovirus (MNV) ORF1 polyprotein is sufficient to induce apoptosis in a virus-free cell model. PLoS ONE. 2014;9:e90679 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:400
- western blot; mouse
| Battle M, Gillespie C, Quarshie A, Lanier V, Harmon T, Wilson K, et al. Obesity induced a leptin-Notch signaling axis in breast cancer. Int J Cancer. 2014;134:1605-16 pubmed publisher |
- western blot; human; fig 5
| Brouxhon S, Kyrkanides S, Teng X, O Banion M, Clarke R, Byers S, et al. Soluble-E-cadherin activates HER and IAP family members in HER2+ and TNBC human breast cancers. Mol Carcinog. 2014;53:893-906 pubmed publisher |
| Martínez García D, Pérez Hernández M, Korrodi Gregório L, Quesada R, Ramos R, Baixeras N, et al. The Natural-Based Antitumor Compound T21 Decreases Survivin Levels through Potent STAT3 Inhibition in Lung Cancer Models. Biomolecules. 2019;9: pubmed publisher |
| Carugo A, Minelli R, Sapio L, Soeung M, Carbone F, Robinson F, et al. p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors. Cancer Cell. 2019;35:204-220.e9 pubmed publisher |
| Day T, Kallakury B, Ross J, Voronel O, Vaidya S, Sheehan C, et al. Dual Targeting of EGFR and IGF1R in the TNFAIP8 Knockdown Non-Small Cell Lung Cancer Cells. Mol Cancer Res. 2019;17:1207-1219 pubmed publisher |
| Zerboni L, Sung P, Lee G, Arvin A. Age-Associated Differences in Infection of Human Skin in the SCID Mouse Model of Varicella-Zoster Virus Pathogenesis. J Virol. 2018;92: pubmed publisher |
| Tanaka N, Patel A, Tang L, Silver N, Lindemann A, Takahashi H, et al. Replication Stress Leading to Apoptosis within the S-phase Contributes to Synergism between Vorinostat and AZD1775 in HNSCC Harboring High-Risk TP53 Mutation. Clin Cancer Res. 2017;23:6541-6554 pubmed publisher |
| Mittal K, Donthamsetty S, Kaur R, Yang C, Gupta M, Reid M, et al. Multinucleated polyploidy drives resistance to Docetaxel chemotherapy in prostate cancer. Br J Cancer. 2017;116:1186-1194 pubmed publisher |
| Nunes J, Pandey S, Yadav A, Goel S, Ateeq B. Targeting NF-kappa B Signaling by Artesunate Restores Sensitivity of Castrate-Resistant Prostate Cancer Cells to Antiandrogens. Neoplasia. 2017;19:333-345 pubmed publisher |
| Lee P, Zhu Z, Hachmann J, Nojima T, Kitamura D, Salvesen G, et al. Differing Requirements for MALT1 Function in Peripheral B Cell Survival and Differentiation. J Immunol. 2017;198:1066-1080 pubmed publisher |
| Yao C, Chow J, Lin P, Hu T, Kuo H, Huang J, et al. Activation of p53/miR-34a Tumor Suppressor Axis by Chinese Herbal Formula JP-1 in A549 Lung Adenocarcinoma Cells. Evid Based Complement Alternat Med. 2016;2016:5989681 pubmed publisher |
| Wang Y, Li D, Luo J, Tian G, Zhao L, Liao D. Intrinsic cellular signaling mechanisms determine the sensitivity of cancer cells to virus-induced apoptosis. Sci Rep. 2016;6:37213 pubmed publisher |
| Lv C, Zhao G, Sun X, Wang P, Xie N, Luo J, et al. Acetylation of FOXM1 is essential for its transactivation and tumor growth stimulation. Oncotarget. 2016;7:60366-60382 pubmed publisher |
| Wu J, Guo W, Lin S, Wang Z, Kan J, Chen S, et al. Gp130-mediated STAT3 activation by S-propargyl-cysteine, an endogenous hydrogen sulfide initiator, prevents doxorubicin-induced cardiotoxicity. Cell Death Dis. 2016;7:e2339 pubmed publisher |
| Guo F, Yu T, Hong J, Fang J. Emerging Roles of Hydrogen Sulfide in Inflammatory and Neoplastic Colonic Diseases. Front Physiol. 2016;7:156 pubmed publisher |
| Vermeulen J, Van Hecke W, Spliet W, Villacorta Hidalgo J, Fisch P, Broekhuizen R, et al. Pediatric Primitive Neuroectodermal Tumors of the Central Nervous System Differentially Express Granzyme Inhibitors. PLoS ONE. 2016;11:e0151465 pubmed publisher |
| Kim S, Park S, Shim S, Park S, Kim K, Jeong S, et al. Bay 61-3606 Sensitizes TRAIL-Induced Apoptosis by Downregulating Mcl-1 in Breast Cancer Cells. PLoS ONE. 2015;10:e0146073 pubmed publisher |
| Zhu J, Sun C, Wang L, Xu M, Zang Y, Zhou Y, et al. Targeting survivin using a combination of miR‑494 and survivin shRNA has synergistic effects on the suppression of prostate cancer growth. Mol Med Rep. 2016;13:1602-10 pubmed publisher |
| Cheng C, Cheng Y, Chang I, Chen H, Wu C, Hsieh C. Dodecyl gallate induces apoptosis by upregulating the caspase-dependent apoptotic pathway and inhibiting the expression of anti-apoptotic Bcl-2 family proteins in human osteosarcoma cells. Mol Med Rep. 2016;13:1495-500 pubmed publisher |
| Nie X, Ou Yang J, Xing Y, Li D, Dong X, Liu R, et al. Paeoniflorin inhibits human glioma cells via STAT3 degradation by the ubiquitin-proteasome pathway. Drug Des Devel Ther. 2015;9:5611-22 pubmed publisher |
| Martinez R, Blasina A, Hallin J, Hu W, Rymer I, Fan J, et al. Mitotic Checkpoint Kinase Mps1 Has a Role in Normal Physiology which Impacts Clinical Utility. PLoS ONE. 2015;10:e0138616 pubmed publisher |
| Debeb B, Smith D, Li L, Larson R, Xu W, Woodward W. Differential effect of phosphorylation-defective survivin on radiation response in estrogen receptor-positive and -negative breast cancer. PLoS ONE. 2015;10:e0120719 pubmed publisher |
| Wei W, Li L, Wang X, Yan L, Cao W, Zhan Z, et al. Overexpression of caudal type homeobox transcription factor 2 inhibits the growth of the MGC-803 human gastric cancer cell line in vivo. Mol Med Rep. 2015;12:905-12 pubmed publisher |
| Sun D, Sawada A, Nakashima M, Kobayashi T, Ogawa O, Matsui Y. MK2206 potentiates cisplatin-induced cytotoxicity and apoptosis through an interaction of inactivated Akt signaling pathway. Urol Oncol. 2015;33:111.e17-26 pubmed publisher |
| Han X, Wang J, Shen Y, Zhang N, Wang S, Yao J, et al. CRM1 as a new therapeutic target for non-Hodgkin lymphoma. Leuk Res. 2015;39:38-46 pubmed publisher |
| Hodgson M, Deryugina E, Suarez E, Lopez S, Lin D, Xue H, et al. INPP4B suppresses prostate cancer cell invasion. Cell Commun Signal. 2014;12:61 pubmed publisher |
| Bhansali M, Shemshedini L. COP9 subunits 4 and 5 target soluble guanylyl cyclase ?1 and p53 in prostate cancer cells. Mol Endocrinol. 2014;28:834-45 pubmed publisher |
| Balboula A, Schindler K. Selective disruption of aurora C kinase reveals distinct functions from aurora B kinase during meiosis in mouse oocytes. PLoS Genet. 2014;10:e1004194 pubmed publisher |
| Li T, Zhang Q, Zhang J, Yang G, Shao Z, Luo J, et al. Fenofibrate induces apoptosis of triple-negative breast cancer cells via activation of NF-?B pathway. BMC Cancer. 2014;14:96 pubmed publisher |
| Chiang Y, Wang K, Fazli L, Qi R, Gleave M, Collins C, et al. GATA2 as a potential metastasis-driving gene in prostate cancer. Oncotarget. 2014;5:451-61 pubmed |
| Ng G, Yeh L, Zhang Y, Liu H, Feng G, Kao W, et al. Role of SH2-containing tyrosine phosphatase Shp2 in mouse corneal epithelial stratification. Invest Ophthalmol Vis Sci. 2013;54:7933-42 pubmed publisher |
| Murata S, Shiragami R, Kosugi C, Tezuka T, Yamazaki M, Hirano A, et al. Antitumor effect of 1, 8-cineole against colon cancer. Oncol Rep. 2013;30:2647-52 pubmed publisher |
| Hu S, Qu Y, Xu X, Xu Q, Geng J, Xu J. Nuclear survivin and its relationship to DNA damage repair genes in non-small cell lung cancer investigated using tissue array. PLoS ONE. 2013;8:e74161 pubmed publisher |
| Li X, Yu C, Wang Z, Zhang Y, Liu X, Zhou D, et al. DNA topoisomerase II is dispensable for oocyte meiotic resumption but is essential for meiotic chromosome condensation and separation in mice. Biol Reprod. 2013;89:118 pubmed publisher |
| Xie H, Lee L, Caramuta S, Höög A, Browaldh N, Björnhagen V, et al. MicroRNA expression patterns related to merkel cell polyomavirus infection in human merkel cell carcinoma. J Invest Dermatol. 2014;134:507-517 pubmed publisher |
| Burton D, Giribaldi M, Muñoz A, Halvorsen K, Patel A, Jorda M, et al. Androgen deprivation-induced senescence promotes outgrowth of androgen-refractory prostate cancer cells. PLoS ONE. 2013;8:e68003 pubmed publisher |
| Peltzer N, Vanli G, Yang J, Widmann C. Role of mTOR, Bad, and Survivin in RasGAP Fragment N-Mediated Cell Protection. PLoS ONE. 2013;8:e68123 pubmed publisher |
| Bernasconi M, Ueda S, Krukowski P, Bornhauser B, Ladell K, Dorner M, et al. Early gene expression changes by Epstein-Barr virus infection of B-cells indicate CDKs and survivin as therapeutic targets for post-transplant lymphoproliferative diseases. Int J Cancer. 2013;133:2341-50 pubmed publisher |
| Nair S, Marlow F, ABRAMS E, KAPP L, Mullins M, Pelegri F. The chromosomal passenger protein birc5b organizes microfilaments and germ plasm in the zebrafish embryo. PLoS Genet. 2013;9:e1003448 pubmed publisher |
| Reiner T, Parrondo R, de las Pozas A, Palenzuela D, Perez Stable C. Betulinic acid selectively increases protein degradation and enhances prostate cancer-specific apoptosis: possible role for inhibition of deubiquitinase activity. PLoS ONE. 2013;8:e56234 pubmed publisher |
| Jin H, Hong S, Woo S, Lee J, Choe T, Kim E, et al. Silencing of Twist1 sensitizes NSCLC cells to cisplatin via AMPK-activated mTOR inhibition. Cell Death Dis. 2012;3:e319 pubmed publisher |
| Rubio N, Garcia Segura L, Arevalo M. Survivin prevents apoptosis by binding to caspase-3 in astrocytes infected with the BeAn strain of Theiler's murine encephalomyelitis virus. J Neurovirol. 2012;18:354-63 pubmed publisher |
| Jacob N, Cooley J, Shirai K, Chakravarti A. Survivin splice variants are not essential for mitotic progression or inhibition of apoptosis induced by doxorubicin and radiation. Onco Targets Ther. 2012;5:7-20 pubmed publisher |
| May K, Paton J, Paton A. Escherichia coli subtilase cytotoxin induces apoptosis regulated by host Bcl-2 family proteins Bax/Bak. Infect Immun. 2010;78:4691-6 pubmed publisher |
| Roca H, Varsos Z, Pienta K. CCL2 is a negative regulator of AMP-activated protein kinase to sustain mTOR complex-1 activation, survivin expression, and cell survival in human prostate cancer PC3 cells. Neoplasia. 2009;11:1309-17 pubmed |
| Williams C, Helguero L, Edvardsson K, Haldosén L, Gustafsson J. Gene expression in murine mammary epithelial stem cell-like cells shows similarities to human breast cancer gene expression. Breast Cancer Res. 2009;11:R26 pubmed publisher |
