product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
ATR Antibody
catalog :
2790S
quantity :
100 ul
price :
235 USD
clonality :
polyclonal
host :
rabbit
reactivity :
human, mouse, rat, dog, chicken, cow
application :
western blot, immunocytochemistry, immunoprecipitation
citations: 13
Published Application/Species/DilutionReference
  • western blot; human
Xue L, Furusawa Y, Okayasu R, Miura M, Cui X, Liu C, et al. The complexity of DNA double strand break is a crucial factor for activating ATR signaling pathway for G2/M checkpoint regulation regardless of ATM function. DNA Repair (Amst). 2015;25:72-83 pubmed publisher
  • western blot; human
Sokka M, Rilla K, Miinalainen I, Pospiech H, Syvaoja J. High levels of TopBP1 induce ATR-dependent shut-down of rRNA transcription and nucleolar segregation. Nucleic Acids Res. 2015;43:4975-89 pubmed publisher
  • western blot; human; fig 1a
Hilton B, Li Z, Musich P, Wang H, Cartwright B, SERRANO M, et al. ATR Plays a Direct Antiapoptotic Role at Mitochondria, which Is Regulated by Prolyl Isomerase Pin1. Mol Cell. 2015;60:35-46 pubmed publisher
  • immunocytochemistry; human
  • western blot; human
Adeyemi R, Pintel D. The ATR signaling pathway is disabled during infection with the parvovirus minute virus of mice. J Virol. 2014;88:10189-99 pubmed publisher
  • western blot; human
Lin B, Gupta D, Heinen C. Human pluripotent stem cells have a novel mismatch repair-dependent damage response. J Biol Chem. 2014;289:24314-24 pubmed publisher
  • western blot; chicken
  • western blot; human
Tuul M, Kitao H, Iimori M, Matsuoka K, Kiyonari S, Saeki H, et al. Rad9, Rad17, TopBP1 and claspin play essential roles in heat-induced activation of ATR kinase and heat tolerance. PLoS ONE. 2013;8:e55361 pubmed publisher
  • western blot; human
Rajendran P, Kidane A, Yu T, Dashwood W, Bisson W, LOHR C, et al. HDAC turnover, CtIP acetylation and dysregulated DNA damage signaling in colon cancer cells treated with sulforaphane and related dietary isothiocyanates. Epigenetics. 2013;8:612-23 pubmed publisher
  • western blot; human
Ding G, Liu H, Liang H, Ni R, Ding Z, Ni G, et al. HIF1-regulated ATRIP expression is required for hypoxia induced ATR activation. FEBS Lett. 2013;587:930-5 pubmed publisher
  • western blot; human; 1:2500
Valdez B, Nieto Y, Murray D, Li Y, Wang G, Champlin R, et al. Epigenetic modifiers enhance the synergistic cytotoxicity of combined nucleoside analog-DNA alkylating agents in lymphoma cell lines. Exp Hematol. 2012;40:800-10 pubmed publisher
  • western blot; human
Sakasai R, Sakai A, Iimori M, Kiyonari S, Matsuoka K, Kakeji Y, et al. CtIP- and ATR-dependent FANCJ phosphorylation in response to DNA strand breaks mediated by DNA replication. Genes Cells. 2012;17:962-70 pubmed publisher
Yang H, Wu L, Ke S, Wang W, Yang L, Gao X, et al. Downregulation of Ubiquitin-conjugating Enzyme UBE2D3 Promotes Telomere Maintenance and Radioresistance of Eca-109 Human Esophageal Carcinoma Cells. J Cancer. 2016;7:1152-62 pubmed publisher
Hou Y, Wang Y, Wang Y, Zhong T, Li L, Zhang H, et al. Multiple alternative splicing and differential expression pattern of the glycogen synthase kinase-3β (GSK3β) gene in goat (Capra hircus). PLoS ONE. 2014;9:e109555 pubmed publisher
Deng Y, Guo X, Ferguson D, Chang S. Multiple roles for MRE11 at uncapped telomeres. Nature. 2009;460:914-8 pubmed publisher
product information
SKU :
2790S
Product-Name :
ATR Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Hm, Mk, (B, Dg)
Applications :
Immunoprecipitation
Product-Category :
Cell Cycle / Checkpoint Control
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
300
Host :
Rabbit
Target :
ATR
Primary-Protein :
ATR
Alt-Names :
ATR,Ataxia telangiectasia and Rad3-related protein,FRAP-related protein 1,FRAP-related protein-1,FRP1,MEC1,MEC1, mitosis entry checkpoint 1, homolog,Rad3 related protein,SCKL,SCKL1,Serine/threonine-protein kinase ATR,ataxia telangiectasia and Rad3 related,protein kinase ATR
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.