product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
ATR Antibody
catalog :
2790
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dogs, bovine
application :
western blot, immunoprecipitation, immunohistochemistry - paraffin section
citations: 13
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 3k
Tu Q, Liu X, Yao X, Li R, Liu G, Jiang H, et al. RETSAT associates with DDX39B to promote fork restarting and resistance to gemcitabine based chemotherapy in pancreatic ductal adenocarcinoma. J Exp Clin Cancer Res. 2022;41:274 pubmed publisher
  • western blot; human; loading ...; fig 2b
Boucher D, Kariawasam R, Burgess J, Gimenez A, Ocampo T, Ferguson B, et al. hSSB2 (NABP1) is required for the recruitment of RPA during the cellular response to DNA UV damage. Sci Rep. 2021;11:20256 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 4e, s9a
Laine A, Nagelli S, Farrington C, Butt U, Cvrljevic A, Vainonen J, et al. CIP2A Interacts with TopBP1 and Drives Basal-Like Breast Cancer Tumorigenesis. Cancer Res. 2021;81:4319-4331 pubmed publisher
  • western blot; mouse; loading ...; fig 2e
Atashpaz S, Samadi Shams S, Gonzalez J, Sebestyén E, Arghavanifard N, Gnocchi A, et al. ATR expands embryonic stem cell fate potential in response to replication stress. elife. 2020;9: pubmed publisher
  • western blot; mouse; fig 6a
Gross K, Zhou W, Breindel J, Ouyang J, Jin D, Sokol E, et al. Loss of Slug Compromises DNA Damage Repair and Accelerates Stem Cell Aging in Mammary Epithelium. Cell Rep. 2019;28:394-407.e6 pubmed publisher
  • western blot; human; loading ...; fig 1a
Savva C, De Souza K, Ali R, Rakha E, Green A, Madhusudan S. Clinicopathological significance of ataxia telangiectasia-mutated (ATM) kinase and ataxia telangiectasia-mutated and Rad3-related (ATR) kinase in MYC overexpressed breast cancers. Breast Cancer Res Treat. 2019;175:105-115 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 4c
Parisotto M, Grelet E, El Bizri R, Dai Y, Terzic J, Eckert D, et al. PTEN deletion in luminal cells of mature prostate induces replication stress and senescence in vivo. J Exp Med. 2018;215:1749-1763 pubmed publisher
  • western blot; human; loading ...; fig 2a, 2b
Karanika S, Karantanos T, Li L, Wang J, Park S, Yang G, et al. Targeting DNA Damage Response in Prostate Cancer by Inhibiting Androgen Receptor-CDC6-ATR-Chk1 Signaling. Cell Rep. 2017;18:1970-1981 pubmed publisher
  • western blot; mouse; loading ...; fig 5b
Kariolis M, Miao Y, Diep A, Nash S, Olcina M, Jiang D, et al. Inhibition of the GAS6/AXL pathway augments the efficacy of chemotherapies. J Clin Invest. 2017;127:183-198 pubmed publisher
  • western blot; human; fig s2
Hong X, Liu W, Song R, Shah J, Feng X, Tsang C, et al. SOX9 is targeted for proteasomal degradation by the E3 ligase FBW7 in response to DNA damage. Nucleic Acids Res. 2016;44:8855-8869 pubmed
  • western blot; human; fig 3d
Peng Y, Miao H, Wu S, Yang W, Zhang Y, Xie G, et al. ABHD5 interacts with BECN1 to regulate autophagy and tumorigenesis of colon cancer independent of PNPLA2. Autophagy. 2016;12:2167-2182 pubmed
  • western blot; human; 1:1000; fig 8
Yang H, Wu L, Ke S, Wang W, Yang L, Gao X, et al. Downregulation of Ubiquitin-conjugating Enzyme UBE2D3 Promotes Telomere Maintenance and Radioresistance of Eca-109 Human Esophageal Carcinoma Cells. J Cancer. 2016;7:1152-62 pubmed publisher
Gao X, Wang W, Yang H, Wu L, He Z, Zhou S, et al. UBE2D3 gene overexpression increases radiosensitivity of EC109 esophageal cancer cells in vitro and in vivo. Oncotarget. 2016;7:32543-53 pubmed publisher
product information
SKU :
2790S
Product-Name :
ATR Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Hm, Mk, (B, Dg)
Applications :
Immunoprecipitation
Product-Category :
Cell Cycle / Checkpoint Control
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
300
Host :
Rabbit
Target :
ATR
Primary-Protein :
ATR
Alt-Names :
ATR,Ataxia telangiectasia and Rad3-related protein,FRAP-related protein 1,FRAP-related protein-1,FRP1,MEC1,MEC1, mitosis entry checkpoint 1, homolog,Rad3 related protein,SCKL,SCKL1,Serine/threonine-protein kinase ATR,ataxia telangiectasia and Rad3 related,protein kinase ATR
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.