| Published Application/Species/Dilution | Reference |
|---|
- immunohistochemistry; rat; fig 4
- western blot; rat; 1:1000; fig 3
| Lai C, Tsai C, Kuo W, Ho T, Day C, Pai P, et al. Multi-Strain Probiotics Inhibit Cardiac Myopathies and Autophagy to Prevent Heart Injury in High-Fat Diet-Fed Rats. Int J Med Sci. 2016;13:277-85 pubmed publisher |
- western blot; human; 1:1000; fig 3
| Yu L, Wu W, Gu C, Zhong D, Zhao X, Kong Y, et al. Obatoclax impairs lysosomal function to block autophagy in cisplatin-sensitive and -resistant esophageal cancer cells. Oncotarget. 2016;7:14693-707 pubmed publisher |
- western blot; human; fig 3
| Phelps-Polirer K, Abt M, Smith D, Yeh E. Co-Targeting of JNK and HUNK in Resistant HER2-Positive Breast Cancer. PLoS ONE. 2016;11:e0153025 pubmed publisher |
- immunocytochemistry; mouse; fig 4
- western blot; mouse; fig s1
| Gómez-Sánchez R, Yakhine-Diop S, Bravo-San Pedro J, Pizarro-Estrella E, Rodríguez-Arribas M, Climent V, et al. PINK1 deficiency enhances autophagy and mitophagy induction. Mol Cell Oncol. 2016;3:e1046579 pubmed publisher |
- western blot; chicken; fig 7
| Droubi A, Bulley S, Clarke J, Irvine R. Nuclear localizations of Phosphatidylinositol-5-phosphate 4-kinases α and β are dynamic and independently regulated during starvation-induced stress. Biochem J. 2016;: pubmed |
- immunocytochemistry; human; fig 5
| Jennewein L, Ronellenfitsch M, Antonietti P, Ilina E, Jung J, Stadel D, et al. Diagnostic and clinical relevance of the autophago-lysosomal network in human gliomas. Oncotarget. 2016;7:20016-32 pubmed publisher |
- western blot; mouse; 1:1000; fig 2
| Xie C, Ginet V, Sun Y, Koike M, Zhou K, Li T, et al. Neuroprotection by selective neuronal deletion of Atg7 in neonatal brain injury. Autophagy. 2016;12:410-23 pubmed publisher |
- western blot; human; fig 1
| Dey A, Mustafi S, Saha S, Kumar Dhar Dwivedi S, Mukherjee P, Bhattacharya R. Inhibition of BMI1 induces autophagy-mediated necroptosis. Autophagy. 2016;12:659-70 pubmed publisher |
- western blot; rat; 1:500; fig 2
| Lesmana R, Sinha R, Singh B, Zhou J, Ohba K, Wu Y, et al. Thyroid Hormone Stimulation of Autophagy Is Essential for Mitochondrial Biogenesis and Activity in Skeletal Muscle. Endocrinology. 2016;157:23-38 pubmed publisher |
- immunohistochemistry - frozen section; mouse; 1:1000; tbl 1
| Krishnan V, White Z, McMahon C, Hodgetts S, Fitzgerald M, Shavlakadze T, et al. A Neurogenic Perspective of Sarcopenia: Time Course Study of Sciatic Nerves From Aging Mice. J Neuropathol Exp Neurol. 2016;75:464-78 pubmed publisher |
- western blot; human; fig 5
| Lei Y, Kansy B, Li J, Cong L, Liu Y, Trivedi S, et al. EGFR-targeted mAb therapy modulates autophagy in head and neck squamous cell carcinoma through NLRX1-TUFM protein complex. Oncogene. 2016;: pubmed publisher |
- western blot; mouse; fig 3
- immunocytochemistry; mouse; fig 3
| Hamlin A, Basford J, Jaeschke A, Hui D. Low density lipoprotein receptor-related protein-1 deficiency exacerbates palmitate-induced steatosis and toxicity in hepatocytes. J Biol Chem. 2016;: pubmed |
- western blot; human; fig 4
| Huang Y, Chen Y, Lai Y, Cheng C, Lin T, Su Y, et al. Resveratrol alleviates the cytotoxicity induced by the radiocontrast agent, ioxitalamate, by reducing the production of reactive oxygen species in HK-2 human renal proximal tubule epithelial cells in vitro. Int J Mol Med. 2016;37:83-91 pubmed publisher |
- western blot; human; fig s1
| Karvela M, Baquero P, Kuntz E, Mukhopadhyay A, Mitchell R, Allan E, et al. ATG7 regulates energy metabolism, differentiation and survival of Philadelphia-chromosome-positive cells. Autophagy. 2016;12:936-48 pubmed publisher |
| Liu L, Zou P, Zheng L, Linarelli L, Amarell S, Passaro A, et al. Tamoxifen reduces fat mass by boosting reactive oxygen species. Cell Death Dis. 2015;6:e1586 pubmed publisher |
| Yang H, Ma Y, Zhou Y, Xu L, Chen X, Ding W, et al. Autophagy contributes to the enrichment and survival of colorectal cancer stem cells under oxaliplatin treatment. Cancer Lett. 2015;361:128-36 pubmed publisher |
- immunocytochemistry; human
| Pène V, Li Q, Sodroski C, Hsu C, Liang T. Dynamic Interaction of Stress Granules, DDX3X, and IKK-α Mediates Multiple Functions in Hepatitis C Virus Infection. J Virol. 2015;89:5462-77 pubmed publisher |
| Noritake K, Aki T, Funakoshi T, Unuma K, Uemura K. Direct Exposure to Ethanol Disrupts Junctional Cell-Cell Contact and Hippo-YAP Signaling in HL-1 Murine Atrial Cardiomyocytes. PLoS ONE. 2015;10:e0136952 pubmed publisher |
| Pantazi E, Zaouali M, Bejaoui M, Folch-Puy E, Ben Abdennebi H, Varela A, et al. Sirtuin 1 in rat orthotopic liver transplantation: an IGL-1 preservation solution approach. World J Gastroenterol. 2015;21:1765-74 pubmed publisher |
- western blot; human; fig 1d
| Kharaziha P, Chioureas D, Baltatzis G, Fonseca P, Rodriguez P, Gogvadze V, et al. Sorafenib-induced defective autophagy promotes cell death by necroptosis. Oncotarget. 2015;6:37066-82 pubmed publisher |
- immunocytochemistry; human; fig s2
- western blot; human; 1:1000; fig s2
| Lu W, Han L, Su L, Zhao J, Zhang Y, Zhang S, et al. A 3'UTR-associated RNA, FLJ11812 maintains stemness of human embryonic stem cells by targeting miR-4459. Stem Cells Dev. 2015;24:1133-40 pubmed publisher |
- western blot; human; 1:1000; fig 3
| Bauckman K, Haller E, Taran N, Rockfield S, RUIZ-RIVERA A, Nanjundan M. Iron alters cell survival in a mitochondria-dependent pathway in ovarian cancer cells. Biochem J. 2015;466:401-13 pubmed publisher |
- western blot; mouse; 1:1000; fig 1
| Qiao S, Dennis M, Song X, Vadysirisack D, Salunke D, Nash Z, et al. A REDD1/TXNIP pro-oxidant complex regulates ATG4B activity to control stress-induced autophagy and sustain exercise capacity. Nat Commun. 2015;6:7014 pubmed publisher |
- immunocytochemistry; human; fig 2
| Crauwels P, Bohn R, Thomas M, Gottwalt S, Jäckel F, Krämer S, et al. Apoptotic-like Leishmania exploit the host's autophagy machinery to reduce T-cell-mediated parasite elimination. Autophagy. 2015;11:285-97 pubmed publisher |
- immunocytochemistry; human; 1:50
| Durán I, Nevarez L, Sarukhanov A, Wu S, Lee K, Krejci P, et al. HSP47 and FKBP65 cooperate in the synthesis of type I procollagen. Hum Mol Genet. 2015;24:1918-28 pubmed publisher |
| Ruan Y, Hu K, Chen H. Autophagy inhibition enhances isorhamnetin‑induced mitochondria‑dependent apoptosis in non‑small cell lung cancer cells. Mol Med Rep. 2015;12:5796-806 pubmed publisher |
- immunocytochemistry; human
| Sharifi M, Mowers E, Drake L, Macleod K. Measuring autophagy in stressed cells. Methods Mol Biol. 2015;1292:129-50 pubmed publisher |
- western blot; human; 1:1000
| Fiorini C, Cordani M, Gotte G, Picone D, Donadelli M. Onconase induces autophagy sensitizing pancreatic cancer cells to gemcitabine and activates Akt/mTOR pathway in a ROS-dependent manner. Biochim Biophys Acta. 2015;1853:549-60 pubmed publisher |
- western blot; human; 1:1000
| Li C, Siragy H. (Pro)renin receptor regulates autophagy and apoptosis in podocytes exposed to high glucose. Am J Physiol Endocrinol Metab. 2015;309:E302-10 pubmed publisher |
- western blot; rat; 1:1000; fig 3g
| Zhang J, Tripathi D, Jing J, Alexander A, Kim J, Powell R, et al. ATM functions at the peroxisome to induce pexophagy in response to ROS. Nat Cell Biol. 2015;17:1259-69 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:200
- western blot; mouse; 1:1000
| Huang Z, Han Z, Ye B, Dai Z, Shan P, Lu Z, et al. Berberine alleviates cardiac ischemia/reperfusion injury by inhibiting excessive autophagy in cardiomyocytes. Eur J Pharmacol. 2015;762:1-10 pubmed publisher |
- western blot; human; 1:500
| Prosser S, Morrison C. Centrin2 regulates CP110 removal in primary cilium formation. J Cell Biol. 2015;208:693-701 pubmed publisher |
- immunocytochemistry; rat; 1:400; fig 4
- western blot; rat; 1:1000; fig 1
| Wang L, Hao H, Wang J, Wang X, Zhang S, Du Y, et al. Decreased autophagy: a major factor for cardiomyocyte death induced by β1-adrenoceptor autoantibodies. Cell Death Dis. 2015;6:e1862 pubmed publisher |
- immunocytochemistry; human; 1:400
| Wiggins H, Wymant J, Solfa F, Hiscox S, Taylor K, Westwell A, et al. Disulfiram-induced cytotoxicity and endo-lysosomal sequestration of zinc in breast cancer cells. Biochem Pharmacol. 2015;93:332-42 pubmed publisher |
- western blot; human; fig 4
| Eriksen A, Torgersen M, Holm K, Abrahamsen G, Spurkland A, Moskaug J, et al. Retinoic acid-induced IgG production in TLR-activated human primary B cells involves ULK1-mediated autophagy. Autophagy. 2015;11:460-71 pubmed publisher |
- western blot; mouse; fig 3
| Antonucci L, Fagman J, Kim J, Todoric J, Gukovsky I, Mackey M, et al. Basal autophagy maintains pancreatic acinar cell homeostasis and protein synthesis and prevents ER stress. Proc Natl Acad Sci U S A. 2015;112:E6166-74 pubmed publisher |
- western blot; mouse; fig 3e
| Xie C, Wei D, Zhao L, Marchetto S, Mei L, Borg J, et al. Erbin is a novel substrate of the Sag-βTrCP E3 ligase that regulates KrasG12D-induced skin tumorigenesis. J Cell Biol. 2015;209:721-37 pubmed publisher |
- western blot; human; 1:1000; fig 4
| Cañeque T, Gomes F, Mai T, Maestri G, Malacria M, Rodriguez R. Synthesis of marmycin A and investigation into its cellular activity. Nat Chem. 2015;7:744-51 pubmed publisher |
- western blot; human
- immunocytochemistry; human
| Luo M, Wong S, Chan M, Yu L, Yu S, Wu F, et al. Autophagy Mediates HBx-Induced Nuclear Factor-κB Activation and Release of IL-6, IL-8, and CXCL2 in Hepatocytes. J Cell Physiol. 2015;230:2382-9 pubmed publisher |
- immunocytochemistry; mouse
| Lin L, Xu J, Ye Y, Ge J, Zou Y, Liu X. Isosorbide dinitrate inhibits mechanical stress-induced cardiac hypertrophy and autophagy through downregulation of angiotensin II type 1 receptor. J Cardiovasc Pharmacol. 2015;65:1-7 pubmed publisher |
| Szalai P, Hagen L, Sætre F, Luhr M, Sponheim M, Øverbye A, et al. Autophagic bulk sequestration of cytosolic cargo is independent of LC3, but requires GABARAPs. Exp Cell Res. 2015;333:21-38 pubmed publisher |
- other; mouse; 1:500; fig s1
| Chiang C, Uzoma I, Lane D, Memisevic V, Alem F, Yao K, et al. A reverse-phase protein microarray-based screen identifies host signaling dynamics upon Burkholderia spp. infection. Front Microbiol. 2015;6:683 pubmed publisher |
| Wang S, Chen X, Hu J, Jiang J, Li Y, Chan-Salis K, et al. ATF4 Gene Network Mediates Cellular Response to the Anticancer PAD Inhibitor YW3-56 in Triple-Negative Breast Cancer Cells. Mol Cancer Ther. 2015;14:877-88 pubmed publisher |
- immunocytochemistry; mouse; 1:100; fig s7
| Kaushik S, Cuervo A. Degradation of lipid droplet-associated proteins by chaperone-mediated autophagy facilitates lipolysis. Nat Cell Biol. 2015;17:759-70 pubmed publisher |
- western blot; mouse; fig f6
| Chung J, Bauer D, Ghamari A, Nizzi C, Deck K, Kingsley P, et al. The mTORC1/4E-BP pathway coordinates hemoglobin production with L-leucine availability. Sci Signal. 2015;8:ra34 pubmed publisher |
- western blot; mouse; fig 3b
| Mir S, George N, Zahoor L, Harms R, Guinn Z, SARVETNICK N. Inhibition of autophagic turnover in β-cells by fatty acids and glucose leads to apoptotic cell death. J Biol Chem. 2015;290:6071-85 pubmed publisher |
| Opperman C, Sishi B. Tumor necrosis factor alpha stimulates p62 accumulation and enhances proteasome activity independently of ROS. Cell Biol Toxicol. 2015;31:83-94 pubmed publisher |
- western blot; human; 1:1000; fig 1
- western blot; mouse; 1:1000; fig 2
| Pedro J, Wei Y, Sica V, Maiuri M, Zou Z, Kroemer G, et al. BAX and BAK1 are dispensable for ABT-737-induced dissociation of the BCL2-BECN1 complex and autophagy. Autophagy. 2015;11:452-9 pubmed publisher |
- immunocytochemistry; human; fig s2,5a
| Drießen S, Berleth N, Friesen O, Löffler A, Böhler P, Hieke N, et al. Deubiquitinase inhibition by WP1130 leads to ULK1 aggregation and blockade of autophagy. Autophagy. 2015;11:1458-70 pubmed publisher |
- immunohistochemistry; rat; 1:100
- western blot; rat; 1:1000
| Carloni S, Albertini M, Galluzzi L, Buonocore G, Proietti F, Balduini W. Increased autophagy reduces endoplasmic reticulum stress after neonatal hypoxia-ischemia: role of protein synthesis and autophagic pathways. Exp Neurol. 2014;255:103-12 pubmed publisher |
| Hamouda M, Belhacene N, Puissant A, Colosetti P, Robert G, Jacquel A, et al. The small heat shock protein B8 (HSPB8) confers resistance to bortezomib by promoting autophagic removal of misfolded proteins in multiple myeloma cells. Oncotarget. 2014;5:6252-66 pubmed |
- immunocytochemistry; rat
- western blot; rat
| Lin L, Tang C, Xu J, Ye Y, Weng L, Wei W, et al. Mechanical stress triggers cardiomyocyte autophagy through angiotensin II type 1 receptor-mediated p38MAP kinase independently of angiotensin II. PLoS ONE. 2014;9:e89629 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; fig 7
- western blot; mouse; fig 6
| Costes S, Gurlo T, Rivera J, Butler P. UCHL1 deficiency exacerbates human islet amyloid polypeptide toxicity in β-cells: evidence of interplay between the ubiquitin/proteasome system and autophagy. Autophagy. 2014;10:1004-14 pubmed publisher |
- immunocytochemistry; human; fig 4
- western blot; human; fig 1
| Rovetta A, Peña D, Hernández Del Pino R, Recalde G, Pellegrini J, Bigi F, et al. IFNG-mediated immune responses enhance autophagy against Mycobacterium tuberculosis antigens in patients with active tuberculosis. Autophagy. 2014;10:2109-21 pubmed publisher |
| Chang P, Wang T, Chang Y, Chu C, Lee C, Hsu H, et al. Autophagy pathway is required for IL-6 induced neuroendocrine differentiation and chemoresistance of prostate cancer LNCaP cells. PLoS ONE. 2014;9:e88556 pubmed publisher |
- western blot; human; 1:2000
| Mancias J, Wang X, Gygi S, Harper J, Kimmelman A. Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy. Nature. 2014;509:105-9 pubmed publisher |
- western blot; mouse; 1:1000; fig 1d
| Gassen N, Hartmann J, Zschocke J, Stepan J, Häfner K, Zellner A, et al. Association of FKBP51 with priming of autophagy pathways and mediation of antidepressant treatment response: evidence in cells, mice, and humans. PLoS Med. 2014;11:e1001755 pubmed publisher |
- western blot; human; 1:2000; fig 7d
- western blot; mouse; 1:2000; fig 4a
| BOWMAN C, Ayer D, Dynlacht B. Foxk proteins repress the initiation of starvation-induced atrophy and autophagy programs. Nat Cell Biol. 2014;16:1202-14 pubmed publisher |
- western blot; rat; 1:1,000
| Edrey Y, Oddo S, Cornelius C, Caccamo A, Calabrese V, Buffenstein R. Oxidative damage and amyloid-β metabolism in brain regions of the longest-lived rodents. J Neurosci Res. 2014;92:195-205 pubmed publisher |
- western blot; Caenorhabditis elegans; fig 4
| Guo B, Huang J, Wu W, Feng D, Wang X, Chen Y, et al. The nascent polypeptide-associated complex is essential for autophagic flux. Autophagy. 2014;10:1738-48 pubmed publisher |
- western blot; mouse; fig 5, 7
| Zemljic-Harpf A, Godoy J, Platoshyn O, Asfaw E, Busija A, Domenighetti A, et al. Vinculin directly binds zonula occludens-1 and is essential for stabilizing connexin-43-containing gap junctions in cardiac myocytes. J Cell Sci. 2014;127:1104-16 pubmed publisher |
| Mellor K, Varma U, Stapleton D, Delbridge L. Cardiomyocyte glycophagy is regulated by insulin and exposure to high extracellular glucose. Am J Physiol Heart Circ Physiol. 2014;306:H1240-5 pubmed publisher |
- western blot; human; fig 3
| Lau H, Ramanujulu P, Guo D, Yang T, Wirawan M, Casey P, et al. An improved isoprenylcysteine carboxylmethyltransferase inhibitor induces cancer cell death and attenuates tumor growth in vivo. Cancer Biol Ther. 2014;15:1280-91 pubmed publisher |
- immunocytochemistry; African green monkey
- western blot; mouse
| Brot S, Auger C, Bentata R, Rogemond V, Ménigoz S, Chounlamountri N, et al. Collapsin response mediator protein 5 (CRMP5) induces mitophagy, thereby regulating mitochondrion numbers in dendrites. J Biol Chem. 2014;289:2261-76 pubmed publisher |
- immunocytochemistry; human; fig 1
| Guo H, Chitiprolu M, Gagnon D, Meng L, Perez-Iratxeta C, Lagace D, et al. Autophagy supports genomic stability by degrading retrotransposon RNA. Nat Commun. 2014;5:5276 pubmed publisher |
| Sisinni L, Maddalena F, Lettini G, Condelli V, Matassa D, Esposito F, et al. TRAP1 role in endoplasmic reticulum stress protection favors resistance to anthracyclins in breast carcinoma cells. Int J Oncol. 2014;44:573-82 pubmed publisher |
| Watanabe M, Funakoshi T, Unuma K, Aki T, Uemura K. Activation of the ubiquitin-proteasome system against arsenic trioxide cardiotoxicity involves ubiquitin ligase Parkin for mitochondrial homeostasis. Toxicology. 2014;322:43-50 pubmed publisher |
| Gómez-Sánchez R, Gegg M, Bravo-San Pedro J, Niso-Santano M, Alvarez-Erviti L, Pizarro-Estrella E, et al. Mitochondrial impairment increases FL-PINK1 levels by calcium-dependent gene expression. Neurobiol Dis. 2014;62:426-40 pubmed publisher |
- western blot; mouse; 1:1000; fig 4
| Nassif M, Valenzuela V, Rojas-Rivera D, Vidal R, Matus S, Castillo K, et al. Pathogenic role of BECN1/Beclin 1 in the development of amyotrophic lateral sclerosis. Autophagy. 2014;10:1256-71 pubmed publisher |
| McGinnis L, Pelech S, Kinsey W. Post-ovulatory aging of oocytes disrupts kinase signaling pathways and lysosome biogenesis. Mol Reprod Dev. 2014;81:928-45 pubmed publisher |
- western blot; mouse; 1:1000
| Bejarano E, Yuste A, Patel B, Stout R, Spray D, Cuervo A. Connexins modulate autophagosome biogenesis. Nat Cell Biol. 2014;16:401-14 pubmed publisher |
- western blot; human; fig 1
| Maruyama Y, Sou Y, Kageyama S, Takahashi T, Ueno T, Tanaka K, et al. LC3B is indispensable for selective autophagy of p62 but not basal autophagy. Biochem Biophys Res Commun. 2014;446:309-15 pubmed publisher |
- western blot; human; 1:1000
- immunocytochemistry; human; 1:100
| Giansanti V, Rodriguez G, Savoldelli M, Gioia R, Forlino A, Mazzini G, et al. Characterization of stress response in human retinal epithelial cells. J Cell Mol Med. 2013;17:103-15 pubmed publisher |
- western blot; rat; 1:1000
| Posimo J, Titler A, Choi H, Unnithan A, Leak R. Neocortex and allocortex respond differentially to cellular stress in vitro and aging in vivo. PLoS ONE. 2013;8:e58596 pubmed publisher |
- western blot; mouse; 1:1000
| Chittoor V, Sooyeon L, Rangaraju S, Nicks J, Schmidt J, Madorsky I, et al. Biochemical characterization of protein quality control mechanisms during disease progression in the C22 mouse model of CMT1A. ASN Neuro. 2013;5:e00128 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:400
| Domitrovic R, Cvijanovic O, Pernjak-Pugel E, Skoda M, Mikelić L, Crncevic-Orlic Z. Berberine exerts nephroprotective effect against cisplatin-induced kidney damage through inhibition of oxidative/nitrosative stress, inflammation, autophagy and apoptosis. Food Chem Toxicol. 2013;62:397-406 pubmed publisher |
- western blot; human; 1:1000
| Bauckman K, Haller E, Flores I, Nanjundan M. Iron modulates cell survival in a Ras- and MAPK-dependent manner in ovarian cells. Cell Death Dis. 2013;4:e592 pubmed publisher |
- flow cytometry; pig; 1:300
- western blot; pig
- immunocytochemistry; pig; 1:200
| Yang Z, Xu Y, Xu L, Maccauro G, Rossi B, Chen Y, et al. Regulation of autophagy via PERK-eIF2α effectively relieve the radiation myelitis induced by iodine-125. PLoS ONE. 2013;8:e76819 pubmed publisher |
- western blot; human; 1:500
- immunocytochemistry; human; 1:100
| Kyathanahalli C, Marks J, Nye K, Lao B, Albrecht E, Aberdeen G, et al. Cross-species withdrawal of MCL1 facilitates postpartum uterine involution in both the mouse and baboon. Endocrinology. 2013;154:4873-84 pubmed publisher |
- immunocytochemistry; human; 1:200
| Itakura A, McCarty O. Pivotal role for the mTOR pathway in the formation of neutrophil extracellular traps via regulation of autophagy. Am J Physiol Cell Physiol. 2013;305:C348-54 pubmed publisher |
- immunocytochemistry; mouse
| Walls K, Ghosh A, Franklin A, Klocke B, Ballestas M, Shacka J, et al. Lysosome dysfunction triggers Atg7-dependent neural apoptosis. J Biol Chem. 2010;285:10497-507 pubmed publisher |
- western blot; human; 1:1000
| Suetta C, Frandsen U, Jensen L, Jensen M, Jespersen J, Hvid L, et al. Aging affects the transcriptional regulation of human skeletal muscle disuse atrophy. PLoS ONE. 2012;7:e51238 pubmed publisher |
- immunocytochemistry; mouse; 1:400
- western blot; mouse; 1:1000
| Durieux A, Vassilopoulos S, Laine J, Fraysse B, Brinas L, Prudhon B, et al. A centronuclear myopathy--dynamin 2 mutation impairs autophagy in mice. Traffic. 2012;13:869-79 pubmed publisher |
| van Geldermalsen M, Wang Q, Nagarajah R, Marshall A, Thoeng A, Gao D, et al. ASCT2/SLC1A5 controls glutamine uptake and tumour growth in triple-negative basal-like breast cancer. Oncogene. 2016;35:3201-8 pubmed publisher |
| Sanongkiet S, Ponnikorn S, Udomsangpetch R, Tungpradabkul S. Burkholderia pseudomallei rpoS mediates iNOS suppression in human hepatocyte (HC04) cells. FEMS Microbiol Lett. 2016;363: pubmed publisher |
| Dong W, Xiao S, Cheng M, Ye X, Zheng G. Minocycline induces protective autophagy in vascular endothelial cells exposed to an in vitro model of ischemia/reperfusion-induced injury. Biomed Rep. 2016;4:173-177 pubmed |
| Yeo S, Itahana Y, Guo A, Han R, Iwamoto K, Nguyen H, et al. Transglutaminase 2 contributes to a TP53-induced autophagy program to prevent oncogenic transformation. elife. 2016;5: pubmed publisher |
| Wang J, Wu J, Wu H, Liu X, Chen Y, Wu J, et al. Liraglutide protects pancreatic β-cells against free fatty acids in vitro and affects glucolipid metabolism in apolipoprotein E-/- mice by activating autophagy. Mol Med Rep. 2015;12:4210-8 pubmed publisher |
| Chandra P, Ghanwat S, Matta S, Yadav S, Mehta M, Siddiqui Z, et al. Mycobacterium tuberculosis Inhibits RAB7 Recruitment to Selectively Modulate Autophagy Flux in Macrophages. Sci Rep. 2015;5:16320 pubmed publisher |
| Pulliero A, Seydel A, Camoirano A, Saccà S, Sandri M, Izzotti A. Oxidative damage and autophagy in the human trabecular meshwork as related with ageing. PLoS ONE. 2014;9:e98106 pubmed publisher |
| Cullup T, Kho A, Dionisi-Vici C, Brandmeier B, Smith F, Urry Z, et al. Recessive mutations in EPG5 cause Vici syndrome, a multisystem disorder with defective autophagy. Nat Genet. 2013;45:83-7 pubmed publisher |
| Hung T, Hsieh T, Chen S, Li M, Yeh Y. Autophagy in the human placenta throughout gestation. PLoS ONE. 2013;8:e83475 pubmed publisher |
| Fang L, Zhou Y, Cao H, Wen P, Jiang L, He W, et al. Autophagy attenuates diabetic glomerular damage through protection of hyperglycemia-induced podocyte injury. PLoS ONE. 2013;8:e60546 pubmed publisher |
| Orenstein S, Kuo S, Tasset I, Arias E, Koga H, Fernandez-Carasa I, et al. Interplay of LRRK2 with chaperone-mediated autophagy. Nat Neurosci. 2013;16:394-406 pubmed publisher |
| Meng Y, Yong Y, Yang G, Ding H, Fan Z, Tang Y, et al. Autophagy alleviates neurodegeneration caused by mild impairment of oxidative metabolism. J Neurochem. 2013;126:805-18 pubmed publisher |
| Alexander A, Cai S, Kim J, Nanez A, Sahin M, Maclean K, et al. ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS. Proc Natl Acad Sci U S A. 2010;107:4153-8 pubmed publisher |
| Chen Y, Kao C, Chen Y, Wang C, Wu C, Tsai C, et al. Cisd2 deficiency drives premature aging and causes mitochondria-mediated defects in mice. Genes Dev. 2009;23:1183-94 pubmed publisher |
| Wen H, Gris D, Lei Y, JHA S, Zhang L, Huang M, et al. Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling. Nat Immunol. 2011;12:408-15 pubmed publisher |
| Li C, Liu H, Sun Y, Wang H, Guo F, Rao S, et al. PAMAM nanoparticles promote acute lung injury by inducing autophagic cell death through the Akt-TSC2-mTOR signaling pathway. J Mol Cell Biol. 2009;1:37-45 pubmed publisher |
| Deuretzbacher A, Czymmeck N, Reimer R, Trulzsch K, Gaus K, Hohenberg H, et al. Beta1 integrin-dependent engulfment of Yersinia enterocolitica by macrophages is coupled to the activation of autophagy and suppressed by type III protein secretion. J Immunol. 2009;183:5847-60 pubmed publisher |
| Mabuchi S, Kawase C, Altomare D, Morishige K, Sawada K, Hayashi M, et al. mTOR is a promising therapeutic target both in cisplatin-sensitive and cisplatin-resistant clear cell carcinoma of the ovary. Clin Cancer Res. 2009;15:5404-13 pubmed publisher |
| Tousif S, Singh Y, Prasad D, Sharma P, Van Kaer L, Das G. T cells from Programmed Death-1 deficient mice respond poorly to Mycobacterium tuberculosis infection. PLoS ONE. 2011;6:e19864 pubmed publisher |
| Balakumaran B, Porrello A, Hsu D, Glover W, Foye A, Leung J, et al. MYC activity mitigates response to rapamycin in prostate cancer through eukaryotic initiation factor 4E-binding protein 1-mediated inhibition of autophagy. Cancer Res. 2009;69:7803-10 pubmed publisher |
| Roca H, Varsos Z, Sud S, Craig M, Ying C, Pienta K. CCL2 and interleukin-6 promote survival of human CD11b+ peripheral blood mononuclear cells and induce M2-type macrophage polarization. J Biol Chem. 2009;284:34342-54 pubmed publisher |
| Tong Y, Giaime E, Yamaguchi H, Ichimura T, Liu Y, Si H, et al. Loss of leucine-rich repeat kinase 2 causes age-dependent bi-phasic alterations of the autophagy pathway. Mol Neurodegener. 2012;7:2 pubmed publisher |
| Han W, Pan H, Chen Y, Sun J, Wang Y, Li J, et al. EGFR tyrosine kinase inhibitors activate autophagy as a cytoprotective response in human lung cancer cells. PLoS ONE. 2011;6:e18691 pubmed publisher |
| Hung T, Chen S, Lo L, Li M, Yeh Y, Hsieh T. Increased autophagy in placentas of intrauterine growth-restricted pregnancies. PLoS ONE. 2012;7:e40957 pubmed publisher |
