Published Application/Species/Sample/Dilution | Reference |
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- western blot; mouse; 1:1000; loading ...; fig 5c
| Shyam R, Ogando D, Choi M, Liton P, Bonanno J. Mitochondrial ROS Induced Lysosomal Dysfunction and Autophagy Impairment in an Animal Model of Congenital Hereditary Endothelial Dystrophy. Invest Ophthalmol Vis Sci. 2021;62:15 pubmed publisher
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- western blot; mouse; 1:1000; fig 5g
| Zeng H, Chen H, Li M, Zhuang J, Peng Y, Zhou H, et al. Autophagy protein NRBF2 attenuates endoplasmic reticulum stress-associated neuroinflammation and oxidative stress via promoting autophagosome maturation by interacting with Rab7 after SAH. J Neuroinflammation. 2021;18:210 pubmed publisher
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- western blot; human; 1:1000; fig s6a
| Hu D, Sun X, Magpusao A, Fedorov Y, Thompson M, Wang B, et al. Small-molecule suppression of calpastatin degradation reduces neuropathology in models of Huntington's disease. Nat Commun. 2021;12:5305 pubmed publisher
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- immunocytochemistry; human; 1:100; loading ...; fig 2e
- western blot; human; 1:500; loading ...; fig 2c
| Ashok A, Chaudhary S, Wise A, Rana N, McDonald D, Kritikos A, et al. Release of Iron-Loaded Ferritin in Sodium Iodate-Induced Model of Age Related Macular Degeneration: An In-Vitro and In-Vivo Study. Antioxidants (Basel). 2021;10: pubmed publisher
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- western blot; human; loading ...
| Yuan T, Annamalai K, Naik S, Lupse B, Geravandi S, Pal A, et al. The Hippo kinase LATS2 impairs pancreatic β-cell survival in diabetes through the mTORC1-autophagy axis. Nat Commun. 2021;12:4928 pubmed publisher
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- western blot; human; 1:1000; loading ...; fig 4a
- western blot; mouse; 1:1000; loading ...; fig 1a, 2b
| Chen C, Wang S, Yu L, Mueller J, Fortunato F, Rausch V, et al. H2O2-mediated autophagy during ethanol metabolism. Redox Biol. 2021;46:102081 pubmed publisher
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- immunocytochemistry; mouse; 1:100; fig s4c
- western blot; mouse; 1:1000; fig s4a
| Coudert L, Osseni A, Gangloff Y, Schaeffer L, Leblanc P. The ESCRT-0 subcomplex component Hrs/Hgs is a master regulator of myogenesis via modulation of signaling and degradation pathways. BMC Biol. 2021;19:153 pubmed publisher
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- western blot; human; 1:1000; loading ...; fig 2k
| Wu Q, Tian A, Li B, Leduc M, Forveille S, Hamley P, et al. IGF1 receptor inhibition amplifies the effects of cancer drugs by autophagy and immune-dependent mechanisms. J Immunother Cancer. 2021;9: pubmed publisher
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- western blot; human; 1:500; fig 6b
| Zhang L, He J, Wang J, Liu J, Chen Z, Deng B, et al. Knockout RAGE alleviates cardiac fibrosis through repressing endothelial-to-mesenchymal transition (EndMT) mediated by autophagy. Cell Death Dis. 2021;12:470 pubmed publisher
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- western blot; human; 1:500; loading ...; fig 5e
| Martínez Gutiérrez A, Fernández Duran I, Marazuela Duque A, Simonet N, Yousef I, Martínez Rovira I, et al. Shikimic acid protects skin cells from UV-induced senescence through activation of the NAD+-dependent deacetylase SIRT1. Aging (Albany NY). 2021;13:12308-12333 pubmed publisher
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- western blot; mouse; 1:1000; loading ...; fig 1h
| Caballero B, Bourdenx M, Luengo E, Díaz A, Sohn P, Chen X, et al. Acetylated tau inhibits chaperone-mediated autophagy and promotes tau pathology propagation in mice. Nat Commun. 2021;12:2238 pubmed publisher
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- western blot; human; fig 6b
| Chen Y, Wang R, Huang S, Henson E, Bi J, Gibson S. Erb-b2 Receptor Tyrosine Kinase 2 (ERBB2) Promotes ATG12-Dependent Autophagy Contributing to Treatment Resistance of Breast Cancer Cells. Cancers (Basel). 2021;13: pubmed publisher
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- western blot; mouse; loading ...
| Tan A, PRASAD R, Jho E. TFEB regulates pluripotency transcriptional network in mouse embryonic stem cells independent of autophagy-lysosomal biogenesis. Cell Death Dis. 2021;12:343 pubmed publisher
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- western blot; mouse; 1:1000; loading ...; fig 3a
| Frew J, Nygaard H. Neuropathological and behavioral characterization of aged Grn R493X progranulin-deficient frontotemporal dementia knockin mice. Acta Neuropathol Commun. 2021;9:57 pubmed publisher
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- immunocytochemistry; mouse; 1:200; loading ...; fig 1e
| Liu X, Jiang J, Liao Y, Tang I, Zheng E, Qiu W, et al. Combination Chemo-Immunotherapy for Pancreatic Cancer Using the Immunogenic Effects of an Irinotecan Silicasome Nanocarrier Plus Anti-PD-1. Adv Sci (Weinh). 2021;8:2002147 pubmed publisher
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- western blot; mouse; 1:800; fig 5i
| Affortit C, Casas F, Ladrech S, Ceccato J, Bourien J, Coyat C, et al. Exacerbated age-related hearing loss in mice lacking the p43 mitochondrial T3 receptor. BMC Biol. 2021;19:18 pubmed publisher
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- immunocytochemistry; mouse; 1:200; loading ...; fig 6b
- western blot; mouse; 1:1000; loading ...; fig 6i
| Polanco J, Hand G, Briner A, Li C, Götz J. Exosomes induce endolysosomal permeabilization as a gateway by which exosomal tau seeds escape into the cytosol. Acta Neuropathol. 2021;141:235-256 pubmed publisher
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- immunocytochemistry; human; 1:1000; loading ...; fig s2a
- western blot; human; 1:1000; loading ...; fig s2c
| Zhou L, He R, Fang P, Li M, Yu H, Wang Q, et al. Hepatitis B virus rigs the cellular metabolome to avoid innate immune recognition. Nat Commun. 2021;12:98 pubmed publisher
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- western blot; mouse; 1:1000; loading ...; fig 8a
| Chung L, Liu S, Huang S, Salter D, Lee H, Hsu Y. High phosphate induces skeletal muscle atrophy and suppresses myogenic differentiation by increasing oxidative stress and activating Nrf2 signaling. Aging (Albany NY). 2020;12:21446-21468 pubmed publisher
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- western blot; human; 1:1000; loading ...; fig s3c
| Mahameed M, Boukeileh S, Obiedat A, Darawshi O, Dipta P, Rimon A, et al. Pharmacological induction of selective endoplasmic reticulum retention as a strategy for cancer therapy. Nat Commun. 2020;11:1304 pubmed publisher
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- western blot; zebrafish ; 1:1000; loading ...; fig 3a
| Chávez M, Morales R, Lopez Crisosto C, Roa J, Allende M, Lavandero S. Autophagy Activation in Zebrafish Heart Regeneration. Sci Rep. 2020;10:2191 pubmed publisher
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- western blot; human; loading ...; fig 4a
| Nixon C, Mavigner M, Sampey G, Brooks A, Spagnuolo R, Irlbeck D, et al. Systemic HIV and SIV latency reversal via non-canonical NF-κB signalling in vivo. Nature. 2020;578:160-165 pubmed publisher
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- western blot; human; 1:1000; loading ...; fig 7k, 7i
- western blot; mouse; 1:1000; loading ...; fig 1b, 4f, s7b
| Quach C, Song Y, Guo H, Li S, Maazi H, Fung M, et al. A truncating mutation in the autophagy gene UVRAG drives inflammation and tumorigenesis in mice. Nat Commun. 2019;10:5681 pubmed publisher
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- western blot; mouse; 1:1000; loading ...; fig s3a
| Wu Y, Chen K, Xing G, Li L, Ma B, Hu Z, et al. Phospholipid remodeling is critical for stem cell pluripotency by facilitating mesenchymal-to-epithelial transition. Sci Adv. 2019;5:eaax7525 pubmed publisher
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- western blot; human; 1:1000; loading ...; fig s5b
| Park S, Jeon P, Jun Y, Park J, Lee S, Lee S, et al. Monitoring LC3- or GABARAP-positive autophagic membranes using modified RavZ-based probes. Sci Rep. 2019;9:16593 pubmed publisher
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- immunohistochemistry - paraffin section; rat; loading ...; fig 1d
- immunohistochemistry - frozen section; human; loading ...; fig 5a
- immunocytochemistry; human; loading ...; fig 3e
| Shin H, Park H, Shin N, Kwon H, Yin Y, Hwang J, et al. Pink1-Mediated Chondrocytic Mitophagy Contributes to Cartilage Degeneration in Osteoarthritis. J Clin Med. 2019;8: pubmed publisher
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- western blot; human; 1:1000; loading ...; fig 2a, e1c, e1g
- western blot; mouse; 1:1000; loading ...; fig 4j, 6g, 6k, 8a
| Chen G, Xie W, Nah J, Sauvat A, Liu P, Pietrocola F, et al. 3,4-Dimethoxychalcone induces autophagy through activation of the transcription factors TFE3 and TFEB. EMBO Mol Med. 2019;11:e10469 pubmed publisher
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- western blot; mouse; 1:200; loading ...; fig 4e
| di Meco A, Pratico D. Early-life exposure to high-fat diet influences brain health in aging mice. Aging Cell. 2019;18:e13040 pubmed publisher
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- western blot; mouse; 1:500; loading ...; fig 1g
| Martin Hurtado A, Martin Morales R, Robledinos Antón N, Blanco R, Palacios Blanco I, Lastres Becker I, et al. NRF2-dependent gene expression promotes ciliogenesis and Hedgehog signaling. Sci Rep. 2019;9:13896 pubmed publisher
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- immunocytochemistry; human; loading ...; fig 1b
- western blot; human; loading ...; fig 1g
| Oleinik N, Kim J, Roth B, Selvam S, Gooz M, Johnson R, et al. Mitochondrial protein import is regulated by p17/PERMIT to mediate lipid metabolism and cellular stress. Sci Adv. 2019;5:eaax1978 pubmed publisher
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- western blot; human; loading ...; fig 3c
| Dorsch L, Schuldt M, dos Remedios C, Schinkel A, de Jong P, Michels M, et al. Protein Quality Control Activation and Microtubule Remodeling in Hypertrophic Cardiomyopathy. Cells. 2019;8: pubmed publisher
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- western blot; human; loading ...; fig 6a
| Grossmann D, Berenguer Escuder C, Bellet M, Scheibner D, Bohler J, Massart F, et al. Mutations in RHOT1 Disrupt Endoplasmic Reticulum-Mitochondria Contact Sites Interfering with Calcium Homeostasis and Mitochondrial Dynamics in Parkinson's Disease. Antioxid Redox Signal. 2019;31:1213-1234 pubmed publisher
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- immunocytochemistry; human; loading ...; fig 1c
- western blot; human; loading ...; fig 5a
| Kumar V, Ayasolla K, Jha A, Mishra A, Vashistha H, Lan X, et al. Disrupted APOL1-miR193a Axis Dedifferentiates Podocytes through Autophagy Blockade in APOL1 Risk Milieu. Am J Physiol Cell Physiol. 2019;: pubmed publisher
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- western blot; mouse; 1:500; loading ...; fig 2b
| Saito T, Kuma A, Sugiura Y, Ichimura Y, Obata M, Kitamura H, et al. Autophagy regulates lipid metabolism through selective turnover of NCoR1. Nat Commun. 2019;10:1567 pubmed publisher
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- western blot; human; loading ...; fig 2c
| Zhang J, He J, Johnson J, Rahman F, Gavathiotis E, Cuervo A, et al. Chaperone-Mediated Autophagy Upregulation Rescues Megalin Expression and Localization in Cystinotic Proximal Tubule Cells. Front Endocrinol (Lausanne). 2019;10:21 pubmed publisher
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- immunocytochemistry; human; loading ...; fig s2a
| Dong X, Yang Y, Zhou Y, Bi X, Zhao N, Zhang Z, et al. Glutathione S-transferases P1 protects breast cancer cell from adriamycin-induced cell death through promoting autophagy. Cell Death Differ. 2019;: pubmed publisher
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- immunocytochemistry; human; loading ...; fig e3b
- western blot; human; loading ...; fig 1b
| Nassour J, Radford R, Correia A, Fusté J, Schoell B, Jauch A, et al. Autophagic cell death restricts chromosomal instability during replicative crisis. Nature. 2019;565:659-663 pubmed publisher
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- western blot; human; 1:1000; loading ...; fig 1d
| Chao H, Lin C, Zuo Q, Liu Y, Xiao M, Xu X, et al. Cardiolipin-Dependent Mitophagy Guides Outcome after Traumatic Brain Injury. J Neurosci. 2019;39:1930-1943 pubmed publisher
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- western blot; mouse; loading ...; fig 5e
| Gallot Y, Bohnert K, Straughn A, Xiong G, Hindi S, Kumar A. PERK regulates skeletal muscle mass and contractile function in adult mice. FASEB J. 2019;33:1946-1962 pubmed publisher
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- western blot; human; loading ...; fig 5a
| Cheruiyot A, Li S, Nickless A, Roth R, Fitzpatrick J, You Z. Compound C inhibits nonsense-mediated RNA decay independently of AMPK. PLoS ONE. 2018;13:e0204978 pubmed publisher
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- western blot; human; loading ...; fig s6a
| Song K, Kim J, Lee Y, Bae H, Lee H, Woo S, et al. Mitochondrial reprogramming via ATP5H loss promotes multimodal cancer therapy resistance. J Clin Invest. 2018;128:4098-4114 pubmed publisher
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- western blot; mouse; 1:2000; loading ...; fig 6f
| Pajares M, Rojo A, Arias E, Díaz Carretero A, Cuervo A, Cuadrado A. Transcription factor NFE2L2/NRF2 modulates chaperone-mediated autophagy through the regulation of LAMP2A. Autophagy. 2018;14:1310-1322 pubmed publisher
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- western blot; human; 1:1000; fig s3a
| Chhipa R, Fan Q, Anderson J, Muraleedharan R, Huang Y, Ciraolo G, et al. AMP kinase promotes glioblastoma bioenergetics and tumour growth. Nat Cell Biol. 2018;20:823-835 pubmed publisher
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- western blot; mouse; loading ...; fig 1e
| Perot B, Boussier J, Yatim N, Rossman J, Ingersoll M, Albert M. Autophagy diminishes the early interferon-? response to influenza A virus resulting in differential expression of interferon-stimulated genes. Cell Death Dis. 2018;9:539 pubmed publisher
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- immunocytochemistry; human; 1:200; loading ...; fig 5h
- western blot; human; 1:1000; loading ...; fig 5a
| Lee S, Bazick H, Chittoor Vinod V, Al Salihi M, Xia G, Notterpek L. Elevated Peripheral Myelin Protein 22, Reduced Mitotic Potential, and Proteasome Impairment in Dermal Fibroblasts from Charcot-Marie-Tooth Disease Type 1A Patients. Am J Pathol. 2018;188:728-738 pubmed publisher
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- immunocytochemistry; human; loading ...; fig s7b
- western blot; human; loading ...; fig 5a
| Ni Z, HE J, Wu Y, Hu C, Dai X, Yan X, et al. AKT-mediated phosphorylation of ATG4B impairs mitochondrial activity and enhances the Warburg effect in hepatocellular carcinoma cells. Autophagy. 2018;14:685-701 pubmed publisher
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- immunocytochemistry; mouse; 1:100; loading ...; fig 4g
| Bansal M, Moharir S, Sailasree S, Sirohi K, Sudhakar C, Sarathi D, et al. Optineurin promotes autophagosome formation by recruiting the autophagy-related Atg12-5-16L1 complex to phagophores containing the Wipi2 protein. J Biol Chem. 2018;293:132-147 pubmed publisher
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- immunocytochemistry; human; 1:300; loading ...; fig s4e
| Tseng J, Xie L, Song S, Xie Y, Allen L, Ajit D, et al. The Deacetylase HDAC6 Mediates Endogenous Neuritic Tau Pathology. Cell Rep. 2017;20:2169-2183 pubmed publisher
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- western blot; human; 1:1000; loading ...; fig 1f
| Tan Y, Ci Y, Dai X, Wu F, Guo J, Liu D, et al. Cullin 3SPOP ubiquitin E3 ligase promotes the poly-ubiquitination and degradation of HDAC6. Oncotarget. 2017;8:47890-47901 pubmed publisher
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- western blot; human; 1:1500; loading ...; fig 1b
| Sakamaki J, Wilkinson S, Hahn M, Tasdemir N, O Prey J, Clark W, et al. Bromodomain Protein BRD4 Is a Transcriptional Repressor of Autophagy and Lysosomal Function. Mol Cell. 2017;66:517-532.e9 pubmed publisher
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- western blot; human; loading ...; fig 2a
| Nayar U, Sadek J, Reichel J, Hernandez Hopkins D, Akar G, Barelli P, et al. Identification of a nucleoside analog active against adenosine kinase-expressing plasma cell malignancies. J Clin Invest. 2017;127:2066-2080 pubmed publisher
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- flow cytometry; human; loading ...; fig 10c
| Banerjee B, Koner D, Lal P, Saha N. Unique mitochondrial localization of arginase 1 and 2 in hepatocytes of air-breathing walking catfish, Clarias batrachus and their differential expression patterns under hyper-ammonia stress. Gene. 2017;622:13-22 pubmed publisher
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- western blot; mouse; fig 5a
- western blot; African green monkey; loading ...; fig 9a
| Kaufman D, Papillon J, Larose L, Iwawaki T, Cybulsky A. Deletion of inositol-requiring enzyme-1? in podocytes disrupts glomerular capillary integrity and autophagy. Mol Biol Cell. 2017;28:1636-1651 pubmed publisher
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- immunocytochemistry; human; 1:1000; loading ...; fig s8a
| Kang H, Park J, Choi K, Kim Y, Choi H, Jung C, et al. Chemical screening identifies ATM as a target for alleviating senescence. Nat Chem Biol. 2017;13:616-623 pubmed publisher
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- western blot; mouse; loading ...; fig 6e
| Fajardo V, Gamu D, Mitchell A, Bloemberg D, Bombardier E, Chambers P, et al. Sarcolipin deletion exacerbates soleus muscle atrophy and weakness in phospholamban overexpressing mice. PLoS ONE. 2017;12:e0173708 pubmed publisher
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- western blot; mouse; 1:1000; loading ...; fig 7a
- western blot; human; 1:1000; loading ...; fig 1d
| Kovacs T, Billes V, Komlos M, Hotzi B, Manzéger A, Tarnóci A, et al. The small molecule AUTEN-99 (autophagy enhancer-99) prevents the progression of neurodegenerative symptoms. Sci Rep. 2017;7:42014 pubmed publisher
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- western blot; human; loading ...; fig 2b
| Wolfson R, Chantranupong L, Wyant G, Gu X, Orozco J, Shen K, et al. KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1. Nature. 2017;543:438-442 pubmed publisher
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- immunocytochemistry; human; loading ...; fig 1a
- western blot; human; loading ...; fig 1s1g
| Jung J, Nayak A, Schaeffer V, Starzetz T, Kirsch A, Muller S, et al. Multiplex image-based autophagy RNAi screening identifies SMCR8 as ULK1 kinase activity and gene expression regulator. elife. 2017;6: pubmed publisher
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- immunocytochemistry; mouse; loading ...; fig 6b
- western blot; mouse; 1:2000; loading ...; fig 6a
- western blot; human; 1:2000; loading ...; fig 1a
| Chen S, Jing Y, Kang X, Yang L, Wang D, Zhang W, et al. Histone H2B monoubiquitination is a critical epigenetic switch for the regulation of autophagy. Nucleic Acids Res. 2017;45:1144-1158 pubmed publisher
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- immunoprecipitation; bovine; loading ...; fig 6a
- western blot; bovine; 1:1000; loading ...; fig 5a
| Russo V, Inglese C, Avallone L, Roperto F, Abate C, Zizzo N, et al. Sigma 2 receptor expression levels in blood and bladder from healthy and bladder cancer cattle. Vet Comp Oncol. 2017;15:1503-1512 pubmed publisher
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- immunocytochemistry; mouse; loading ...; fig 4b
- western blot; mouse; loading ...; fig 4a
| Ma K, Fu W, Tang M, Zhang C, Hou T, Li R, et al. PTK2-mediated degradation of ATG3 impedes cancer cells susceptible to DNA damage treatment. Autophagy. 2017;13:579-591 pubmed publisher
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- western blot; human; loading ...; fig 5a
| Ruf S, Heberle A, Langelaar Makkinje M, Gelino S, Wilkinson D, Gerbeth C, et al. PLK1 (polo like kinase 1) inhibits MTOR complex 1 and promotes autophagy. Autophagy. 2017;13:486-505 pubmed publisher
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- immunohistochemistry - frozen section; human; 1:200; loading ...; fig 5c
| Borgia D, Malena A, Spinazzi M, Desbats M, Salviati L, Russell A, et al. Increased mitophagy in the skeletal muscle of spinal and bulbar muscular atrophy patients. Hum Mol Genet. 2017;26:1087-1103 pubmed publisher
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- western blot; mouse; loading ...; fig 5a
- immunohistochemistry; human; loading ...; fig 7b
- western blot; human; loading ...; fig 5j
| Pietrocola F, Demont Y, Castoldi F, Enot D, Durand S, Semeraro M, et al. Metabolic effects of fasting on human and mouse blood in vivo. Autophagy. 2017;13:567-578 pubmed publisher
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- immunocytochemistry; human; loading ...; fig 2b
- western blot; human; loading ...; fig 2a
| Capizzi M, Strappazzon F, Cianfanelli V, Papaleo E, Cecconi F. MIR7-3HG, a MYC-dependent modulator of cell proliferation, inhibits autophagy by a regulatory loop involving AMBRA1. Autophagy. 2017;13:554-566 pubmed publisher
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- western blot; human; 1:1000; loading ...; fig 5a
| Laporte A, Barrott J, Yao R, Poulin N, Brodin B, Jones K, et al. HDAC and Proteasome Inhibitors Synergize to Activate Pro-Apoptotic Factors in Synovial Sarcoma. PLoS ONE. 2017;12:e0169407 pubmed publisher
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- western blot; mouse; 1:1000; loading ...; fig 8a
| Yeung P, Lai A, Son H, Zhang X, Hwang O, Chung S, et al. Aldose reductase deficiency leads to oxidative stress-induced dopaminergic neuronal loss and autophagic abnormality in an animal model of Parkinson's disease. Neurobiol Aging. 2017;50:119-133 pubmed publisher
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- immunohistochemistry; mouse; loading ...; fig 6c
- western blot; mouse; loading ...; fig 6e
- western blot; human; loading ...; fig 6e
| Da Ros M, Lehtiniemi T, Olotu O, Fischer D, Zhang F, Vihinen H, et al. FYCO1 and autophagy control the integrity of the haploid male germ cell-specific RNP granules. Autophagy. 2017;13:302-321 pubmed publisher
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- western blot; rat; fig 3d
- western blot; mouse; loading ...; fig 2a
| Li J, Chen T, Xiao M, Li N, Wang S, Su H, et al. Mouse Sirt3 promotes autophagy in AngII-induced myocardial hypertrophy through the deacetylation of FoxO1. Oncotarget. 2016;7:86648-86659 pubmed publisher
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- western blot; human; fig 2f
| Cramer S, Saha A, Liu J, Tadi S, Tiziani S, Yan W, et al. Systemic depletion of L-cyst(e)ine with cyst(e)inase increases reactive oxygen species and suppresses tumor growth. Nat Med. 2017;23:120-127 pubmed publisher
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- immunocytochemistry; human; loading ...; fig 6a
- immunocytochemistry; African green monkey; loading ...; fig 6b
| Tábara L, Escalante R. VMP1 Establishes ER-Microdomains that Regulate Membrane Contact Sites and Autophagy. PLoS ONE. 2016;11:e0166499 pubmed publisher
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- western blot; mouse; loading ...; fig 3d
| Sakata K, Araki K, Nakano H, Nishina T, Komazawa Sakon S, Murai S, et al. Novel method to rescue a lethal phenotype through integration of target gene onto the X-chromosome. Sci Rep. 2016;6:37200 pubmed publisher
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- western blot; mouse; 1:1000; loading ...; fig s4j
| Cao L, Riascos Bernal D, Chinnasamy P, Dunaway C, Hou R, Pujato M, et al. Control of mitochondrial function and cell growth by the atypical cadherin Fat1. Nature. 2016;539:575-578 pubmed publisher
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- immunohistochemistry - paraffin section; mouse; loading ...; fig 5f
- western blot; mouse; fig 1b
| Han J, Bae J, Choi C, Choi S, Kang H, Jo E, et al. Autophagy induced by AXL receptor tyrosine kinase alleviates acute liver injury via inhibition of NLRP3 inflammasome activation in mice. Autophagy. 2016;12:2326-2343 pubmed
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- western blot; mouse; loading ...
| Liu L, Tao Z, Zheng L, Brooke J, Smith C, Liu D, et al. FoxO1 interacts with transcription factor EB and differentially regulates mitochondrial uncoupling proteins via autophagy in adipocytes. Cell Death Discov. 2016;2:16066 pubmed
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- immunocytochemistry; human; 1:400; fig 5
- western blot; human; 1:400; fig 5
| Wang H, Chen S, Lo W. Identification of Cofilin-1 Induces G0/G1 Arrest and Autophagy in Angiotensin-(1-7)-treated Human Aortic Endothelial Cells from iTRAQ Quantitative Proteomics. Sci Rep. 2016;6:35372 pubmed publisher
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- western blot; mouse; loading ...; fig 6
| Figueroa González G, García Castillo V, Coronel Hernández J, López Urrutia E, León Cabrera S, Arias Romero L, et al. Anti-inflammatory and Antitumor Activity of a Triple Therapy for a Colitis-Related Colorectal Cancer. J Cancer. 2016;7:1632-1644 pubmed
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- immunocytochemistry; human; loading ...; fig 3c
- western blot; human; 1:1000; loading ...; fig 3f
| Wei R, Lin S, Wu W, Chen L, Li C, Chen H, et al. A microtubule inhibitor, ABT-751, induces autophagy and delays apoptosis in Huh-7 cells. Toxicol Appl Pharmacol. 2016;311:88-98 pubmed publisher
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- western blot; mouse; loading ...; fig 1g
| Hubert V, Peschel A, Langer B, Groger M, Rees A, Kain R. LAMP-2 is required for incorporating syntaxin-17 into autophagosomes and for their fusion with lysosomes. Biol Open. 2016;5:1516-1529 pubmed publisher
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- western blot; human; loading ...; fig 7a
| Heulot M, Chevalier N, Puyal J, Margue C, Michel S, Kreis S, et al. The TAT-RasGAP317-326 anti-cancer peptide can kill in a caspase-, apoptosis-, and necroptosis-independent manner. Oncotarget. 2016;7:64342-64359 pubmed publisher
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- immunohistochemistry; mouse; loading ...; fig 3c
- western blot; mouse; loading ...; fig 3b
| Conlon D, Thomas T, Fedotova T, Hernandez Ono A, Di Paolo G, Chan R, et al. Inhibition of apolipoprotein B synthesis stimulates endoplasmic reticulum autophagy that prevents steatosis. J Clin Invest. 2016;126:3852-3867 pubmed publisher
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- western blot; rat; loading ...; fig 2
| Ogasawara R, Fujita S, Hornberger T, Kitaoka Y, Makanae Y, Nakazato K, et al. The role of mTOR signalling in the regulation of skeletal muscle mass in a rodent model of resistance exercise. Sci Rep. 2016;6:31142 pubmed publisher
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- immunocytochemistry; human; 1:200; loading ...; fig 2
- western blot; human; loading ...; fig 4
| Xu S, Law B, Mok S, Leung E, Fan X, Coghi P, et al. Autophagic degradation of epidermal growth factor receptor in gefitinib-resistant lung cancer by celastrol. Int J Oncol. 2016;49:1576-88 pubmed publisher
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- flow cytometry; human; loading ...; fig 5c
- western blot; human; loading ...; fig 5b
| Xing Y, Cao R, Hu H. TLR and NLRP3 inflammasome-dependent innate immune responses to tumor-derived autophagosomes (DRibbles). Cell Death Dis. 2016;7:e2322 pubmed publisher
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- western blot; rat; fig 4c
| Bartlett J, Trivedi P, Yeung P, Kienesberger P, Pulinilkunnil T. Doxorubicin impairs cardiomyocyte viability by suppressing transcription factor EB expression and disrupting autophagy. Biochem J. 2016;473:3769-3789 pubmed
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- western blot; human; loading ...; fig 1a
- immunocytochemistry; mouse; loading ...; fig 2d
- western blot; mouse; loading ...; fig 1b
| Wang J, Zhou J, Kho D, Reiners J, Wu G. Role for DUSP1 (dual-specificity protein phosphatase 1) in the regulation of autophagy. Autophagy. 2016;12:1791-1803 pubmed
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- immunohistochemistry - free floating section; mouse; 1:250; fig 3j
- immunohistochemistry - paraffin section; mouse; 1:250; fig 3j
- western blot; mouse; 1:2000; loading ...; fig 2g
| Pajares M, Jiménez Moreno N, García Yagüe A, Escoll M, De Ceballos M, Van Leuven F, et al. Transcription factor NFE2L2/NRF2 is a regulator of macroautophagy genes. Autophagy. 2016;12:1902-1916 pubmed
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- western blot; mouse; loading ...; fig 1c
| Pan H, Zhong X, Lee S. Sustained activation of mTORC1 in macrophages increases AMPKα-dependent autophagy to maintain cellular homeostasis. BMC Biochem. 2016;17:14 pubmed publisher
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- immunocytochemistry; rat; loading ...; fig 8d
| Bramini M, Sacchetti S, Armirotti A, Rocchi A, Vazquez E, León Castellanos V, et al. Graphene Oxide Nanosheets Disrupt Lipid Composition, Ca(2+) Homeostasis, and Synaptic Transmission in Primary Cortical Neurons. ACS Nano. 2016;10:7154-71 pubmed publisher
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- immunocytochemistry; mouse; fig 3
- western blot; mouse; fig 3
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- immunocytochemistry; mouse; fig 4
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- western blot; mouse; fig 8
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- western blot; mouse; loading ...; fig 4a
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- western blot; chicken; fig 7
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- western blot; human; fig s1
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- immunocytochemistry; human; 1:400; fig 2
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- western blot; human; loading ...; fig s5b
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- immunohistochemistry; rat; fig 4
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- western blot; human; loading ...; fig 7c
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- western blot; human; loading ...; fig 6c
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- immunohistochemistry - frozen section; mouse; 1:1000; tbl 1
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- western blot; mouse; 1:1000; fig s1e
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- western blot; bovine; fig 3a
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- western blot; human; loading ...; fig 2c
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- immunocytochemistry; human; fig 5
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- immunohistochemistry - frozen section; mouse; fig 4
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- western blot; mouse; loading ...; fig 10a
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- immunohistochemistry - free floating section; mouse; fig s16
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- western blot; mouse; loading ...; fig 9
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- western blot; human; fig 4
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- western blot; mouse; loading ...; fig 2a
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