product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Bax Antibody
catalog :
2772S
quantity :
100 ul
price :
235 USD
clonality :
polyclonal
host :
rabbit
reactivity :
human, mouse, rat
application :
western blot, immunoprecipitation
citations: 18
Published Application/Species/DilutionReference
  • western blot (knockout validation); human; fig 1c
  • western blot (knockout validation); mouse; fig 1c
Xu W, Cheng M, Lao Y, Wang X, Wu J, Zhou L, et al. DNA damage and ER stress contribute to oblongifolin C-induced cell killing in Bax/Bak-deficient cells. Biochem Biophys Res Commun. 2015;457:300-6 pubmed publisher
  • western blot; human; 1:1000; fig 5
Bao H, Liu P, Jiang K, Zhang X, Xie L, Wang Z, et al. Huaier polysaccharide induces apoptosis in hepatocellular carcinoma cells through p38 MAPK. Oncol Lett. 2016;12:1058-1066 pubmed
  • western blot; human; fig 9
Urnukhsaikhan E, Cho H, Mishig-Ochir T, Seo Y, Park J. Pulsed electromagnetic fields promote survival and neuronal differentiation of human BM-MSCs. Life Sci. 2016;151:130-8 pubmed publisher
  • western blot; human; 1:1000; tbl 1
Vega-Naredo I, Cunha-Oliveira T, Serafim T, Sardao V, Oliveira P. Analysis of pro-apoptotic protein trafficking to and from mitochondria. Methods Mol Biol. 2015;1241:163-80 pubmed publisher
  • western blot; human; 1:2500
Zhang W, Cai J, Chen S, Zheng X, Hu S, Dong W, et al. Paclitaxel resistance in MCF-7/PTX cells is reversed by paeonol through suppression of the SET/phosphatidylinositol 3-kinase/Akt pathway. Mol Med Rep. 2015;12:1506-14 pubmed publisher
  • western blot; human; 1:8000
Olsen R, Mary-Sinclair M, Yin Z, Freeman K. Antagonizing Bcl-2 family members sensitizes neuroblastoma and Ewing's sarcoma to an inhibitor of glutamine metabolism. PLoS ONE. 2015;10:e0116998 pubmed publisher
  • western blot; human; fig 3
Yang L, Li Y, Bhattacharya A, Zhang Y. Inhibition of ERBB2-overexpressing Tumors by Recombinant Human Prolidase and Its Enzymatically Inactive Mutant. EBioMedicine. 2015;2:396-405 pubmed
  • western blot; human; 1:1000
Zanotto-Filho A, Braganhol E, Klafke K, Figueiró F, Terra S, Paludo F, et al. Autophagy inhibition improves the efficacy of curcumin/temozolomide combination therapy in glioblastomas. Cancer Lett. 2015;358:220-31 pubmed publisher
  • western blot; human
Weilbacher A, Gutekunst M, Oren M, Aulitzky W, van der Kuip H. RITA can induce cell death in p53-defective cells independently of p53 function via activation of JNK/SAPK and p38. Cell Death Dis. 2014;5:e1318 pubmed publisher
  • western blot; human
Kim H, Jung G. Reactive oxygen species increase HEPN1 expression via activation of the XBP1 transcription factor. FEBS Lett. 2014;588:4413-21 pubmed publisher
  • western blot; human
Subramani R, Lopez-Valdez R, Arumugam A, Nandy S, Boopalan T, Lakshmanaswamy R. Targeting insulin-like growth factor 1 receptor inhibits pancreatic cancer growth and metastasis. PLoS ONE. 2014;9:e97016 pubmed publisher
Reddy N, Shoja M, Jayashree B, Nayak P, Kumar N, Prasad V, et al. In vitro and in vivo evaluation of novel cinnamyl sulfonamide hydroxamate derivative against colon adenocarcinoma. Chem Biol Interact. 2015;233:81-94 pubmed publisher
Lin P, Weng X, Liu F, Ma Y, Chen H, Shao X, et al. Bushen Zhuangjin decoction inhibits TM-induced chondrocyte apoptosis mediated by endoplasmic reticulum stress. Int J Mol Med. 2015;36:1519-28 pubmed publisher
Wang L, Liu X, Chen H, Chen Z, Weng X, Qiu T, et al. Effect of picroside II on apoptosis induced by renal ischemia/reperfusion injury in rats. Exp Ther Med. 2015;9:817-822 pubmed
Pritchard J, Gilbert L, Meacham C, Ricks J, Jiang H, Lauffenburger D, et al. Bcl-2 family genetic profiling reveals microenvironment-specific determinants of chemotherapeutic response. Cancer Res. 2011;71:5850-8 pubmed publisher
Ikner A, Ashkenazi A. TWEAK induces apoptosis through a death-signaling complex comprising receptor-interacting protein 1 (RIP1), Fas-associated death domain (FADD), and caspase-8. J Biol Chem. 2011;286:21546-54 pubmed publisher
Widenmaier S, Ao Z, Kim S, Warnock G, McIntosh C. Suppression of p38 MAPK and JNK via Akt-mediated inhibition of apoptosis signal-regulating kinase 1 constitutes a core component of the beta-cell pro-survival effects of glucose-dependent insulinotropic polypeptide. J Biol Chem. 2009;284:30372-82 pubmed publisher
Hung T, Chen S, Lo L, Li M, Yeh Y, Hsieh T. Increased autophagy in placentas of intrauterine growth-restricted pregnancies. PLoS ONE. 2012;7:e40957 pubmed publisher
product information
SKU :
2772S
Product-Name :
Bax Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Immunoprecipitation
Product-Category :
Apoptosis
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
20
Host :
Rabbit
Target :
Bax
Primary-Protein :
Bax
Alt-Names :
Apoptosis regulator BAX,BAX,BCL2-associated X protein,BCL2L4,Bcl-2-like protein 4,Bcl2-L-4
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.