Published Application/Species/Dilution | Reference |
- western blot; human; fig 7
| Urnukhsaikhan E, Cho H, Mishig-Ochir T, Seo Y, Park J. Pulsed electromagnetic fields promote survival and neuronal differentiation of human BM-MSCs. Life Sci. 2016;151:130-8 pubmed publisher
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- western blot; human; fig 2
| Dupont T, Yang S, Patel J, Hatzi K, Malik A, Tam W, et al. Selective targeting of BCL6 induces oncogene addiction switching to BCL2 in B-cell lymphoma. Oncotarget. 2016;7:3520-32 pubmed publisher
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- western blot; mouse; fig 6b
| Tattikota S, Rathjen T, Hausser J, Khedkar A, Kabra U, Pandey V, et al. miR-184 Regulates Pancreatic β-Cell Function According to Glucose Metabolism. J Biol Chem. 2015;290:20284-94 pubmed publisher
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- western blot; rat; 1:1000
| Bing L, Wu J, Zhang J, Chen Y, Hong Z, Zu H. DHT inhibits the Aβ25-35-induced apoptosis by regulation of seladin-1, survivin, XIAP, bax, and bcl-xl expression through a rapid PI3-K/Akt signaling in C6 glial cell lines. Neurochem Res. 2015;40:41-8 pubmed publisher
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- western blot; human; 1:1000; tbl 1
| Vega-Naredo I, Cunha-Oliveira T, Serafim T, Sardao V, Oliveira P. Analysis of pro-apoptotic protein trafficking to and from mitochondria. Methods Mol Biol. 2015;1241:163-80 pubmed publisher
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- western blot; human; fig 5
| Valianou M, Cox A, Pichette B, Hartley S, Paladhi U, Astrinidis A. Pharmacological inhibition of Polo-like kinase 1 (PLK1) by BI-2536 decreases the viability and survival of hamartin and tuberin deficient cells via induction of apoptosis and attenuation of autophagy. Cell Cycle. 2015;14:399-407 pubmed publisher
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| Nakajima W, Hicks M, Tanaka N, Krystal G, Harada H. Noxa determines localization and stability of MCL-1 and consequently ABT-737 sensitivity in small cell lung cancer. Cell Death Dis. 2014;5:e1052 pubmed publisher
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- western blot; human; fig 1
| Klaus C, Kaemmerer E, Reinartz A, Schneider U, Plum P, Jeon M, et al. TP53 status regulates ACSL5-induced expression of mitochondrial mortalin in enterocytes and colorectal adenocarcinomas. Cell Tissue Res. 2014;357:267-78 pubmed publisher
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- western blot; human; 1:500
| Rizvi S, Mertens J, Bronk S, Hirsova P, Dai H, Roberts L, et al. Platelet-derived growth factor primes cancer-associated fibroblasts for apoptosis. J Biol Chem. 2014;289:22835-49 pubmed publisher
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| Shibeeb O, Wood J, Casson R, Chidlow G. Effects of a conventional photocoagulator and a 3-ns pulse laser on preconditioning responses and retinal ganglion cell survival after optic nerve crush. Exp Eye Res. 2014;127:77-90 pubmed publisher
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- western blot; human; 1:1000
| Geissler A, Haun F, Frank D, Wieland K, Simon M, Idzko M, et al. Apoptosis induced by the fungal pathogen gliotoxin requires a triple phosphorylation of Bim by JNK. Cell Death Differ. 2013;20:1317-29 pubmed publisher
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| Lu K, Fang X, Feng L, Jiang Y, Zhou X, Liu X, et al. The STAT3 inhibitor WP1066 reverses the resistance of chronic lymphocytic leukemia cells to histone deacetylase inhibitors induced by interleukin-6. Cancer Lett. 2015;359:250-8 pubmed publisher
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| Miyamoto M, Takano M, Iwaya K, Shinomiya N, Kato M, Aoyama T, et al. X-chromosome-linked inhibitor of apoptosis as a key factor for chemoresistance in clear cell carcinoma of the ovary. Br J Cancer. 2014;110:2881-6 pubmed publisher
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| Denoyelle C, Lambert B, Meryet-Figuiere M, Vigneron N, Brotin E, Lecerf C, et al. miR-491-5p-induced apoptosis in ovarian carcinoma depends on the direct inhibition of both BCL-XL and EGFR leading to BIM activation. Cell Death Dis. 2014;5:e1445 pubmed publisher
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| Granato A, Hayashi E, Baptista B, Bellio M, Nobrega A. IL-4 regulates Bim expression and promotes B cell maturation in synergy with BAFF conferring resistance to cell death at negative selection checkpoints. J Immunol. 2014;192:5761-75 pubmed publisher
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| Meeker S, Seamons A, Paik J, Treuting P, Brabb T, Grady W, et al. Increased dietary vitamin D suppresses MAPK signaling, colitis, and colon cancer. Cancer Res. 2014;74:4398-408 pubmed publisher
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| Nemati F, De Montrion C, Lang G, Kraus-Berthier L, Carita G, Sastre-Garau X, et al. Targeting Bcl-2/Bcl-XL induces antitumor activity in uveal melanoma patient-derived xenografts. PLoS ONE. 2014;9:e80836 pubmed publisher
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| Subrahmanyam P, Carey G, Webb T. Bcl-xL regulates CD1d-mediated antigen presentation to NKT cells by altering CD1d trafficking through the endocytic pathway. J Immunol. 2014;193:2096-105 pubmed publisher
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| Hollevoet K, Antignani A, FitzGerald D, Pastan I. Combining the antimesothelin immunotoxin SS1P with the BH3-mimetic ABT-737 induces cell death in SS1P-resistant pancreatic cancer cells. J Immunother. 2014;37:8-15 pubmed publisher
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| Keitel U, Scheel A, Thomale J, Halpape R, Kaulfuß S, Scheel C, et al. Bcl-xL mediates therapeutic resistance of a mesenchymal breast cancer cell subpopulation. Oncotarget. 2014;5:11778-91 pubmed
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| Zhang J, Herreros-Villanueva M, Herreros-Vilanueva M, Koenig A, Deng Z, de Narvajas A, et al. Differential activity of GSK-3 isoforms regulates NF-κB and TRAIL- or TNFα induced apoptosis in pancreatic cancer cells. Cell Death Dis. 2014;5:e1142 pubmed publisher
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| Guo X, Dong Y, Yin S, Zhao C, Huo Y, Fan L, et al. Patulin induces pro-survival functions via autophagy inhibition and p62 accumulation. Cell Death Dis. 2013;4:e822 pubmed publisher
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| Ha T, Jeon M, Yu D, Lee G. Effect of Bcl-x(L) overexpression on lactate metabolism in chinese hamster ovary cells producing antibody. Biotechnol Prog. 2013;29:1594-8 pubmed publisher
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| Dzieran J, Fabian J, Feng T, Coulouarn C, Ilkavets I, Kyselova A, et al. Comparative analysis of TGF-β/Smad signaling dependent cytostasis in human hepatocellular carcinoma cell lines. PLoS ONE. 2013;8:e72252 pubmed publisher
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| Yuan Y, Tang A, Castoreno A, Kuo S, Wang Q, Kuballa P, et al. Gossypol and an HMT G9a inhibitor act in synergy to induce cell death in pancreatic cancer cells. Cell Death Dis. 2013;4:e690 pubmed publisher
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| Schulman J, Wright F, Kaufmann T, Wojcikiewicz R. The Bcl-2 protein family member Bok binds to the coupling domain of inositol 1,4,5-trisphosphate receptors and protects them from proteolytic cleavage. J Biol Chem. 2013;288:25340-9 pubmed publisher
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| Yi Z, Stunz L, Bishop G. TNF receptor associated factor 3 plays a key role in development and function of invariant natural killer T cells. J Exp Med. 2013;210:1079-86 pubmed publisher
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| Knights A, Fucíková J, Pasam A, Koernig S, Cebon J. Inhibitor of apoptosis protein (IAP) antagonists demonstrate divergent immunomodulatory properties in human immune subsets with implications for combination therapy. Cancer Immunol Immunother. 2013;62:321-35 pubmed publisher
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| Kasper S, Breitenbuecher F, Reis H, Brandau S, Worm K, Kohler J, et al. Oncogenic RAS simultaneously protects against anti-EGFR antibody-dependent cellular cytotoxicity and EGFR signaling blockade. Oncogene. 2013;32:2873-81 pubmed publisher
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| Wong M, Tan N, Zha J, Peale F, Yue P, Fairbrother W, et al. Navitoclax (ABT-263) reduces Bcl-x(L)-mediated chemoresistance in ovarian cancer models. Mol Cancer Ther. 2012;11:1026-35 pubmed publisher
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| Xiang X, Phung Y, Feng M, Nagashima K, Zhang J, Broaddus V, et al. The development and characterization of a human mesothelioma in vitro 3D model to investigate immunotoxin therapy. PLoS ONE. 2011;6:e14640 pubmed publisher
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| Baumgartner C, Yagita H, Malherbe L. A TCR affinity threshold regulates memory CD4 T cell differentiation following vaccination. J Immunol. 2012;189:2309-17 pubmed publisher
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| Miki H, Uehara N, Kimura A, Sasaki T, Yuri T, Yoshizawa K, et al. Resveratrol induces apoptosis via ROS-triggered autophagy in human colon cancer cells. Int J Oncol. 2012;40:1020-8 pubmed publisher
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| van Oosterwijk J, Herpers B, Meijer D, Briaire-de Bruijn I, Cleton-Jansen A, Gelderblom H, et al. Restoration of chemosensitivity for doxorubicin and cisplatin in chondrosarcoma in vitro: BCL-2 family members cause chemoresistance. Ann Oncol. 2012;23:1617-26 pubmed publisher
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| Larsen M, Yde C, Christensen I, Lykkesfeldt A. Carboplatin treatment of antiestrogen-resistant breast cancer cells. Int J Oncol. 2012;41:1863-70 pubmed publisher
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| Zhang X, Weng C, Li Y, Wang X, Jiang C, Li X, et al. Human Bop is a novel BH3-only member of the Bcl-2 protein family. Protein Cell. 2012;3:790-801 pubmed publisher
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