Phospho-Lck (Tyr505) Antibody | Cell Signaling Technology 2751 product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

Phospho-Lck (Tyr505) Antibody

catalog :

2751

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

antigen modification :

phosphorylated

reactivity :

human, mouse

application :

western blot, immunocytochemistry, immunoprecipitation, flow cytometry

more info or order :

Cell Signaling Technology product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; 1:1000; loading ...; fig 6c	Kim H, Mun Y, Lee K, Park Y, Park J, Park J, et al. T cell microvilli constitute immunological synaptosomes that carry messages to antigen-presenting cells. Nat Commun. 2018;9:3630 pubmed publisher
western blot; human; loading ...; fig 7h	Borlido J, Sakuma S, Raices M, Carrette F, Tinoco R, Bradley L, et al. Nuclear pore complex-mediated modulation of TCR signaling is required for naïve CD4+ T cell homeostasis. Nat Immunol. 2018;19:594-605 pubmed publisher
western blot; human; loading ...; fig s6a	Hui E, Cheung J, Zhu J, Su X, Taylor M, Wallweber H, et al. T cell costimulatory receptor CD28 is a primary target for PD-1-mediated inhibition. Science. 2017;355:1428-1433 pubmed publisher
flow cytometry; mouse; fig ev5	Voisinne G, García Blesa A, Chaoui K, Fiore F, Bergot E, Girard L, et al. Co-recruitment analysis of the CBL and CBLB signalosomes in primary T cells identifies CD5 as a key regulator of TCR-induced ubiquitylation. Mol Syst Biol. 2016;12:876 pubmed publisher
western blot; mouse; fig 5	Hu H, Wang H, Xiao Y, Jin J, Chang J, Zou Q, et al. Otud7b facilitates T cell activation and inflammatory responses by regulating Zap70 ubiquitination. J Exp Med. 2016;213:399-414 pubmed publisher
immunocytochemistry; human; fig 5	Cleret Buhot A, Zhang Y, Planas D, Goulet J, Monteiro P, Gosselin A, et al. Identification of novel HIV-1 dependency factors in primary CCR4(+)CCR6(+)Th17 cells via a genome-wide transcriptional approach. Retrovirology. 2015;12:102 pubmed publisher
western blot; mouse	Kaczmarek J, Homsi Y, van Üüm J, Metzger C, Knolle P, Kolanus W, et al. Liver sinusoidal endothelial cell-mediated CD8 T cell priming depends on co-inhibitory signal integration over time. PLoS ONE. 2014;9:e99574 pubmed publisher
	Le Page A, Fortin C, Garneau H, Allard N, Tsvetkova K, Tan C, et al. Downregulation of inhibitory SRC homology 2 domain-containing phosphatase-1 (SHP-1) leads to recovery of T cell responses in elderly. Cell Commun Signal. 2014;12:2 pubmed publisher
	Harr M, Caimi P, McColl K, Zhong F, Patel S, Barr P, et al. Inhibition of Lck enhances glucocorticoid sensitivity and apoptosis in lymphoid cell lines and in chronic lymphocytic leukemia. Cell Death Differ. 2010;17:1381-91 pubmed publisher

product information

SKU :

2751S

Product-Name :

Phospho-Lck (Tyr505) Antibody

Size :

100 ul

Price-(USD) :

274 USD

Species-x-Reactivity :

H, M

Applications :

Immunoprecipitation

Product-Category :

Immunology and Inflammation

Shipping-Temp :

AMBIENT

Storage-Temp :

-20°C

Product-Type :

Polyclonal Antibody

MW :

Host :

Rabbit

Target :

Lck (Tyr505) phosphate

Primary-Protein :

Lck

Alt-Names :

LCK,LSK,Lymphocyte cell-specific protein-tyrosine kinase,Proto-oncogene Lck,T cell-specific protein-tyrosine kinase,T-lymphocyte specific protein tyrosine kinase p56lck,Tyrosine-protein kinase Lck,YT16,lymphocyte-specific protein tyrosine kinase,p56(LSTRA) protein-tyrosine kinase,p56-LCK,p56lck,pp58lck,proto-oncogene tyrosine-protein kinase LCK

more info or order :

Cell Signaling Technology product webpage