product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Sox2 Antibody
catalog :
2748
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dog, cow
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation, immunohistochemistry - paraffin section, other
citations: 23
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; mouse; 1:500; loading ...; fig 4k
Metzis V, Steinhauser S, Pakanavicius E, Gouti M, Stamataki D, Ivanovitch K, et al. Nervous System Regionalization Entails Axial Allocation before Neural Differentiation. Cell. 2018;175:1105-1118.e17 pubmed publisher
  • other; human; loading ...; fig 4c
Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 6h
Chatzeli L, Gaete M, Tucker A. Fgf10 and Sox9 are essential for the establishment of distal progenitor cells during mouse salivary gland development. Development. 2017;144:2294-2305 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 3bb
  • western blot; human; loading ...; fig 2a
Zhang C, Mukherjee S, Tucker Burden C, Ross J, Chau M, Kong J, et al. TRIM8 regulates stemness in glioblastoma through PIAS3-STAT3. Mol Oncol. 2017;11:280-294 pubmed publisher
  • western blot; human; loading ...; fig 4c
Stanford E, Wang Z, Novikov O, Mulas F, Landesman Bollag E, Monti S, et al. The role of the aryl hydrocarbon receptor in the development of cells with the molecular and functional characteristics of cancer stem-like cells. BMC Biol. 2016;14:20 pubmed publisher
  • western blot; mouse; 1:500; fig 3
Murakami K, Günesdogan U, Zylicz J, Tang W, Sengupta R, Kobayashi T, et al. NANOG alone induces germ cells in primed epiblast in vitro by activation of enhancers. Nature. 2016;529:403-407 pubmed publisher
  • western blot; human; fig 2
Kuo H, Hsu H, Chen Y, Chang Y, Liu F, Wu C. Galectin-3 modulates the EGFR signalling-mediated regulation of Sox2 expression via c-Myc in lung cancer. Glycobiology. 2016;26:155-65 pubmed publisher
  • western blot; human; fig 4a
Wongtrakoongate P, Riddick G, Fucharoen S, Felsenfeld G. Association of the Long Non-coding RNA Steroid Receptor RNA Activator (SRA) with TrxG and PRC2 Complexes. PLoS Genet. 2015;11:e1005615 pubmed publisher
  • immunocytochemistry; human; fig 3
Driscoll C, Tonne J, El Khatib M, Cattaneo R, Ikeda Y, Devaux P. Nuclear reprogramming with a non-integrating human RNA virus. Stem Cell Res Ther. 2015;6:48 pubmed publisher
  • immunocytochemistry; human
Peretz Y, Wu H, Patel S, Bellacosa A, Katz R. Inhibitor of DNA Binding 4 (ID4) is highly expressed in human melanoma tissues and may function to restrict normal differentiation of melanoma cells. PLoS ONE. 2015;10:e0116839 pubmed publisher
  • western blot; mouse
Geula S, Moshitch Moshkovitz S, Dominissini D, Mansour A, Kol N, Salmon Divon M, et al. Stem cells. m6A mRNA methylation facilitates resolution of naïve pluripotency toward differentiation. Science. 2015;347:1002-6 pubmed publisher
  • immunocytochemistry; human; 1:500; fig 1
Yu D, Swaroop M, Wang M, Baxa U, Yang R, Yan Y, et al. Niemann-Pick Disease Type C: Induced Pluripotent Stem Cell-Derived Neuronal Cells for Modeling Neural Disease and Evaluating Drug Efficacy. J Biomol Screen. 2014;19:1164-73 pubmed publisher
  • immunohistochemistry; mouse; 1:1000
Piper M, Barry G, Harvey T, McLeay R, Smith A, Harris L, et al. NFIB-mediated repression of the epigenetic factor Ezh2 regulates cortical development. J Neurosci. 2014;34:2921-30 pubmed publisher
Yoon C, Chang K, Lee J, Tap W, Hart C, Simon M, et al. Multimodal targeting of tumor vasculature and cancer stem-like cells in sarcomas with VEGF-A inhibition, HIF-1? inhibition, and hypoxia-activated chemotherapy. Oncotarget. 2016;7:42844-42858 pubmed publisher
El Khatib M, Ohmine S, Jacobus E, Tonne J, Morsy S, Holditch S, et al. Tumor-Free Transplantation of Patient-Derived Induced Pluripotent Stem Cell Progeny for Customized Islet Regeneration. Stem Cells Transl Med. 2016;5:694-702 pubmed publisher
Cheng J, Liu C, Liu L, Chen X, Shan J, Shen J, et al. MEK1 signaling promotes self-renewal and tumorigenicity of liver cancer stem cells via maintaining SIRT1 protein stabilization. Oncotarget. 2016;7:20597-611 pubmed publisher
Ikeda Y, Makino A, Matchett W, Holditch S, Lu B, Dietz A, et al. A novel intranuclear RNA vector system for long-term stem cell modification. Gene Ther. 2016;23:256-62 pubmed publisher
Gaete M, Fons J, Popa E, Chatzeli L, Tucker A. Epithelial topography for repetitive tooth formation. Biol Open. 2015;4:1625-34 pubmed publisher
Gaete M, Tucker A. Organized emergence of multiple-generations of teeth in snakes is dysregulated by activation of Wnt/beta-catenin signalling. PLoS ONE. 2013;8:e74484 pubmed publisher
Singh S, Veo B, Kagalwala M, Shi W, Liang S, Majumder S. Dynamic status of REST in the mouse ESC pluripotency network. PLoS ONE. 2012;7:e43659 pubmed publisher
Gaete M, Mu oz R, S nchez N, Tampe R, Moreno M, Contreras E, et al. Spinal cord regeneration in Xenopus tadpoles proceeds through activation of Sox2-positive cells. Neural Dev. 2012;7:13 pubmed publisher
Ohmine S, Squillace K, Hartjes K, Deeds M, Armstrong A, Thatava T, et al. Reprogrammed keratinocytes from elderly type 2 diabetes patients suppress senescence genes to acquire induced pluripotency. Aging (Albany NY). 2012;4:60-73 pubmed
Thatava T, Nelson T, Edukulla R, Sakuma T, Ohmine S, Tonne J, et al. Indolactam V/GLP-1-mediated differentiation of human iPS cells into glucose-responsive insulin-secreting progeny. Gene Ther. 2011;18:283-93 pubmed publisher
product information
SKU :
2748S
Product-Name :
Sox2 Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, (R, Mk, B, Dg, Hr)
Applications :
Chromatin Immunoprecipitation
Product-Category :
Developmental Biology
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
35
Host :
Rabbit
Target :
Sox2
Primary-Protein :
SOX2
Alt-Names :
ANOP3,MCOPS3,MGC2413,SOX2,SRY (sex determining region Y)-box 2,SRY-related HMG-box gene 2,Transcription factor SOX-2,transcription factor SOX2
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.