product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
c-Cbl Antibody
catalog :
2747
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, cow
application :
western blot, immunocytochemistry, immunoprecipitation, western blot knockout validation
more info or order :
Cell Signaling Technology product webpage
citations: 6
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; mouse; fig 6
Voisinne G, García Blesa A, Chaoui K, Fiore F, Bergot E, Girard L, et al. Co-recruitment analysis of the CBL and CBLB signalosomes in primary T cells identifies CD5 as a key regulator of TCR-induced ubiquitylation. Mol Syst Biol. 2016;12:876 pubmed publisher
  • western blot; mouse; loading ...; fig 1b
Mukhopadhyay C, Triplett A, Bargar T, HECKMAN C, Wagner K, Naramura M. Casitas B-cell lymphoma (Cbl) proteins protect mammary epithelial cells from proteotoxicity of active c-Src accumulation. Proc Natl Acad Sci U S A. 2016;113:E8228-E8237 pubmed publisher
  • western blot; human; loading ...; fig 7
Rorsman C, Tsioumpekou M, Heldin C, Lennartsson J. The Ubiquitin Ligases c-Cbl and Cbl-b Negatively Regulate Platelet-derived Growth Factor (PDGF) BB-induced Chemotaxis by Affecting PDGF Receptor ? (PDGFR?) Internalization and Signaling. J Biol Chem. 2016;291:11608-18 pubmed publisher
  • western blot; mouse; loading ...
Ishibashi T, Yaguchi A, Terada K, Ueno Yokohata H, Tomita O, Iijima K, et al. Ph-like ALL-related novel fusion kinase ATF7IP-PDGFRB exhibits high sensitivity to tyrosine kinase inhibitors in murine cells. Exp Hematol. 2016;44:177-88.e5 pubmed publisher
Nunes J, Zhang H, Angelopoulos N, Chhetri J, Osipo C, Grothey A, et al. ATG9A loss confers resistance to trastuzumab via c-Cbl mediated Her2 degradation. Oncotarget. 2016;7:27599-612 pubmed publisher
Tsai R, Discher D. Inhibition of "self" engulfment through deactivation of myosin-II at the phagocytic synapse between human cells. J Cell Biol. 2008;180:989-1003 pubmed publisher
product information
SKU :
2747S
Product-Name :
c-Cbl Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk, (B)
Applications :
Immunofluorescence (Immunocytochemistry)
Product-Category :
Ubiquitin and Ubiquitin-like proteins
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
120
Host :
Rabbit
Target :
Cbl
Primary-Protein :
Cbl
Alt-Names :
C-CBL,CBL,CBL2,Cas-Br-M (murine) ecotropic retroviral transforming sequence,Casitas B-lineage lymphoma proto-oncogene,E3 ubiquitin-protein ligase CBL,Proto-oncogene c-Cbl,RING finger protein 55,RNF55,Signal transduction protein CBL,oncogene CBL2
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.