product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Zap-70 (99F2) Rabbit mAb
catalog :
2705
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
99F2
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, other
citations: 15
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 7e
Kim C, Park S, Lee S, Kim Y, Jang S, Woo S, et al. NSrp70 is a lymphocyte-essential splicing factor that controls thymocyte development. Nucleic Acids Res. 2021;49:5760-5778 pubmed publisher
  • western blot; human; loading ...; fig 7a
Celis Gutierrez J, Blattmann P, Zhai Y, Jarmuzynski N, Ruminski K, Gregoire C, et al. Quantitative Interactomics in Primary T Cells Provides a Rationale for Concomitant PD-1 and BTLA Coinhibitor Blockade in Cancer Immunotherapy. Cell Rep. 2019;27:3315-3330.e7 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 2d
Sorrelle N, Ganguly D, Dominguez A, Zhang Y, Huang H, Dahal L, et al. Improved Multiplex Immunohistochemistry for Immune Microenvironment Evaluation of Mouse Formalin-Fixed, Paraffin-Embedded Tissues. J Immunol. 2019;202:292-299 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 6c
Kim H, Mun Y, Lee K, Park Y, Park J, Park J, et al. T cell microvilli constitute immunological synaptosomes that carry messages to antigen-presenting cells. Nat Commun. 2018;9:3630 pubmed publisher
  • other; human; loading ...; fig 4c
Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  • western blot; human; loading ...; fig 9a
Kükenshöner T, Schmit N, Bouda E, Sha F, Pojer F, Koide A, et al. Selective Targeting of SH2 Domain-Phosphotyrosine Interactions of Src Family Tyrosine Kinases with Monobodies. J Mol Biol. 2017;429:1364-1380 pubmed publisher
  • western blot; human; loading ...; fig 6c
Kinosada H, Yasunaga J, Shimura K, Miyazato P, Onishi C, Iyoda T, et al. HTLV-1 bZIP Factor Enhances T-Cell Proliferation by Impeding the Suppressive Signaling of Co-inhibitory Receptors. PLoS Pathog. 2017;13:e1006120 pubmed publisher
  • western blot; human
Gusscott S, Jenkins C, Lam S, Giambra V, Pollak M, Weng A. IGF1R Derived PI3K/AKT Signaling Maintains Growth in a Subset of Human T-Cell Acute Lymphoblastic Leukemias. PLoS ONE. 2016;11:e0161158 pubmed publisher
  • western blot; mouse; loading ...; fig 1c
Naik E, Dixit V. Usp9X Is Required for Lymphocyte Activation and Homeostasis through Its Control of ZAP70 Ubiquitination and PKCβ Kinase Activity. J Immunol. 2016;196:3438-51 pubmed publisher
  • immunocytochemistry; human; fig 5
Cleret Buhot A, Zhang Y, Planas D, Goulet J, Monteiro P, Gosselin A, et al. Identification of novel HIV-1 dependency factors in primary CCR4(+)CCR6(+)Th17 cells via a genome-wide transcriptional approach. Retrovirology. 2015;12:102 pubmed publisher
  • western blot; human
Roffé M, Lupinacci F, Soares L, Hajj G, Martins V. Two widely used RSK inhibitors, BI-D1870 and SL0101, alter mTORC1 signaling in a RSK-independent manner. Cell Signal. 2015;27:1630-42 pubmed publisher
  • western blot; human; fig s1
Gasser J, Inuzuka H, Lau A, Wei W, Beroukhim R, Toker A. SGK3 mediates INPP4B-dependent PI3K signaling in breast cancer. Mol Cell. 2014;56:595-607 pubmed publisher
Guittard G, Dios Esponera A, Palmer D, Akpan I, Barr V, Manna A, et al. The Cish SH2 domain is essential for PLC-γ1 regulation in TCR stimulated CD8+ T cells. Sci Rep. 2018;8:5336 pubmed publisher
Troeger A, Chae H, Senturk M, Wood J, Williams D. A unique carboxyl-terminal insert domain in the hematopoietic-specific, GTPase-deficient Rho GTPase RhoH regulates post-translational processing. J Biol Chem. 2013;288:36451-62 pubmed publisher
Chae H, Siefring J, Hildeman D, Gu Y, Williams D. RhoH regulates subcellular localization of ZAP-70 and Lck in T cell receptor signaling. PLoS ONE. 2010;5:e13970 pubmed publisher
product information
SKU :
2705S
Product-Name :
Zap-70 (99F2) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M
Applications :
Flow cytometry
Product-Category :
Immunology and Inflammation
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
70
Host :
Rabbit
Target :
ZAP70
Primary-Protein :
ZAP70
Alt-Names :
70 kDa zeta-associated protein,FLJ17670,FLJ17679,SRK,STD,Syk-related tyrosine kinase,TZK,Tyrosine-protein kinase ZAP-70,ZAP-70,ZAP70,zeta-chain (TCR) associated protein kinase 70kDa,zeta-chain associated protein kinase, 70kD
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.