product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
β-Catenin (L87A12) Mouse mAb
catalog :
2698
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
L87A12
reactivity :
human, mouse, rat
application :
western blot, immunoprecipitation, immunohistochemistry - paraffin section
citations: 10
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:2000; loading ...; fig 3g
Guo H, Li Y, Shen L, Wang T, Jia X, Liu L, et al. Disruptive variants of CSDE1 associate with autism and interfere with neuronal development and synaptic transmission. Sci Adv. 2019;5:eaax2166 pubmed publisher
  • immunoprecipitation; mouse; loading ...; fig 4a
  • western blot; mouse; 1:1000; loading ...; fig 4a
Qin L, Ma K, Wang Z, Hu Z, Matas E, Wei J, et al. Social deficits in Shank3-deficient mouse models of autism are rescued by histone deacetylase (HDAC) inhibition. Nat Neurosci. 2018;21:564-575 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:200
Kim S, Lee E, Kuh H. Co-culture of 3D tumor spheroids with fibroblasts as a model for epithelial-mesenchymal transition in vitro. Exp Cell Res. 2015;335:187-96 pubmed publisher
  • western blot; human; fig 4
Isogai T, van der Kammen R, Innocenti M. SMIFH2 has effects on Formins and p53 that perturb the cell cytoskeleton. Sci Rep. 2015;5:9802 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:1000; loading ...; fig 5
Hsu H, Liu Y, Tseng K, Yang T, Yeh C, You J, et al. CBB1003, a lysine-specific demethylase 1 inhibitor, suppresses colorectal cancer cells growth through down-regulation of leucine-rich repeat-containing G-protein-coupled receptor 5 expression. J Cancer Res Clin Oncol. 2015;141:11-21 pubmed publisher
  • western blot; human; 1:1000
Hsu H, Liu Y, Tseng K, Tan B, Chen S, Chen H. LGR5 regulates survival through mitochondria-mediated apoptosis and by targeting the Wnt/?-catenin signaling pathway in colorectal cancer cells. Cell Signal. 2014;26:2333-42 pubmed publisher
Spencer A, Schaumberg A, Zallen J. Scaling of cytoskeletal organization with cell size in Drosophila. Mol Biol Cell. 2017;28:1519-1529 pubmed publisher
Tang X, Zheng D, Hu P, Zeng Z, Li M, Tucker L, et al. Glycogen synthase kinase 3 beta inhibits microRNA-183-96-182 cluster via the ?-Catenin/TCF/LEF-1 pathway in gastric cancer cells. Nucleic Acids Res. 2014;42:2988-98 pubmed publisher
James R, Bosch K, Kulikauskas R, Yang P, Robin N, Toroni R, et al. Protein kinase PKN1 represses Wnt/?-catenin signaling in human melanoma cells. J Biol Chem. 2013;288:34658-70 pubmed publisher
Abba M, Patil N, Rasheed K, Nelson L, Mudduluru G, Leupold J, et al. Unraveling the role of FOXQ1 in colorectal cancer metastasis. Mol Cancer Res. 2013;11:1017-28 pubmed publisher
product information
SKU :
2698S
Product-Name :
β-Catenin (L87A12) Mouse mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Immunoprecipitation
Product-Category :
Developmental Biology
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
92
Host :
Mouse
Target :
Catenin-beta
Primary-Protein :
CTNNB1
Alt-Names :
Beta-catenin,CTNB1,CTNNB,CTNNB1,Catenin beta-1,DKFZp686D02253,FLJ25606,FLJ37923,catenin (cadherin-associated protein), beta 1, 88kDa
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.