product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
IKKγ (DA10-12) Mouse mAb
catalog :
2695
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
DA10-12
reactivity :
human, mouse, rat
application :
western blot, western blot knockout validation
more info or order :
Cell Signaling Technology product webpage
citations: 7
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; mouse; 1 ug/ml; fig 1
Zhao T, Yang L, Sun Q, Arguello M, Ballard D, Hiscott J, et al. The NEMO adaptor bridges the nuclear factor-kappaB and interferon regulatory factor signaling pathways. Nat Immunol. 2007;8:592-600 pubmed
  • western blot; human; loading ...; fig 3d
Shibata Y, Tokunaga F, Goto E, Komatsu G, Gohda J, Saeki Y, et al. HTLV-1 Tax Induces Formation of the Active Macromolecular IKK Complex by Generating Lys63- and Met1-Linked Hybrid Polyubiquitin Chains. PLoS Pathog. 2017;13:e1006162 pubmed publisher
  • western blot; mouse; 1:1000; fig 2
Maria Z, Campolo A, Lacombe V. Diabetes Alters the Expression and Translocation of the Insulin-Sensitive Glucose Transporters 4 and 8 in the Atria. PLoS ONE. 2015;10:e0146033 pubmed publisher
  • western blot; human
Zhuang C, Sheng C, Shin W, Wu Y, Li J, Yao J, et al. A novel drug discovery strategy: mechanistic investigation of an enantiomeric antitumor agent targeting dual p53 and NF-κB pathways. Oncotarget. 2014;5:10830-9 pubmed
Shibata Y, Oyama M, Kozuka Hata H, Han X, Tanaka Y, Gohda J, et al. p47 negatively regulates IKK activation by inducing the lysosomal degradation of polyubiquitinated NEMO. Nat Commun. 2012;3:1061 pubmed publisher
Lee N, Lira M, Pavlicek A, Ye J, Buckman D, Bagrodia S, et al. A novel SND1-BRAF fusion confers resistance to c-Met inhibitor PF-04217903 in GTL16 cells through [corrected] MAPK activation. PLoS ONE. 2012;7:e39653 pubmed publisher
Biton S, Ashkenazi A. NEMO and RIP1 control cell fate in response to extensive DNA damage via TNF-? feedforward signaling. Cell. 2011;145:92-103 pubmed publisher
product information
SKU :
2695S
Product-Name :
IKKγ (DA10-12) Mouse mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, R
Applications :
Western blot
Product-Category :
Immunology and Inflammation
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
50
Host :
Mouse
Target :
IKK-gamma
Primary-Protein :
IKK-gamma
Alt-Names :
AMCBX1,FIP-3,FIP3,Fip3p,I-kappa-B kinase subunit gamma,IKBKG,IKK-gamma,IKKAP1,IKKG,IP,IP1,IP2,IPD2,IkB kinase gamma subunit,IkB kinase subunit gamma,IkB kinase-associated protein 1,Inhibitor of nuclear factor kappa-B kinase subunit gamma,NEMO,NF-kappa-B essential modifier,NF-kappa-B essential modulator,NFkappaB essential modulator,incontinentia pigmenti,inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.