product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Calnexin (C5C9) Rabbit mAb
catalog :
2679
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
C5C9
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, other
citations: 45
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 1b
Zhang Z, Li X, Yang F, Chen C, Liu P, Ren Y, et al. DHHC9-mediated GLUT1 S-palmitoylation promotes glioblastoma glycolysis and tumorigenesis. Nat Commun. 2021;12:5872 pubmed publisher
  • western blot; human; fig 3b
Lim K, Dayem A, Choi Y, Lee Y, An J, Gil M, et al. High Therapeutic and Esthetic Properties of Extracellular Vesicles Produced from the Stem Cells and Their Spheroids Cultured from Ocular Surgery-Derived Waste Orbicularis Oculi Muscle Tissues. Antioxidants (Basel). 2021;10: pubmed publisher
  • western blot; human; loading ...; fig 3f
Ko P, Choi J, Song S, Keum S, Jeong J, Hwang Y, et al. Microtubule Acetylation Controls MDA-MB-231 Breast Cancer Cell Invasion through the Modulation of Endoplasmic Reticulum Stress. Int J Mol Sci. 2021;22: pubmed publisher
  • immunocytochemistry; human; 1:500; loading ...; fig 3
Watanabe R, Higashi S, Nonaka T, Kawakami I, Oshima K, Niizato K, et al. Intracellular dynamics of Ataxin-2 in the human brains with normal and frontotemporal lobar degeneration with TDP-43 inclusions. Acta Neuropathol Commun. 2020;8:176 pubmed publisher
  • western blot; mouse; loading ...; fig 5k
  • other; human; loading ...; fig 5c, 5e
Wang W, Hu D, Wu C, Feng Y, Li A, Liu W, et al. STING promotes NLRP3 localization in ER and facilitates NLRP3 deubiquitination to activate the inflammasome upon HSV-1 infection. PLoS Pathog. 2020;16:e1008335 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 5f
Crescitelli R, Lässer C, Jang S, Cvjetkovic A, Malmhäll C, Karimi N, et al. Subpopulations of extracellular vesicles from human metastatic melanoma tissue identified by quantitative proteomics after optimized isolation. J Extracell Vesicles. 2020;9:1722433 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 1
Deng M, Chen Z, Tan J, Liu H. Down-regulation of SLC35C1 induces colon cancer through over-activating Wnt pathway. J Cell Mol Med. 2020;24:3079-3090 pubmed publisher
  • western blot; mouse; loading ...; fig s3a
Yang S, Harding A, Sweeney C, Miao D, Swan G, Zhou C, et al. Control of antiviral innate immune response by protein geranylgeranylation. Sci Adv. 2019;5:eaav7999 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 1b
Stefanius K, Servage K, de Souza Santos M, Gray H, Toombs J, Chimalapati S, et al. Human pancreatic cancer cell exosomes, but not human normal cell exosomes, act as an initiator in cell transformation. elife. 2019;8: pubmed publisher
  • western blot; human; 26 ng/ml; loading ...; fig 5d
Choi J, Zhong X, McAlpine W, Liao T, Zhang D, Fang B, et al. LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling. Science. 2019;364: pubmed publisher
  • immunohistochemistry; human; loading ...; fig 6c
Wisskirchen K, Kah J, Malo A, Asen T, Volz T, Allweiss L, et al. T cell receptor grafting allows virological control of Hepatitis B virus infection. J Clin Invest. 2019;129:2932-2945 pubmed publisher
  • immunocytochemistry; human; 1:100; loading ...; fig 2b
Chun J, Zhang J, Wilkins M, Subramanian B, Riella C, Magraner J, et al. Recruitment of APOL1 kidney disease risk variants to lipid droplets attenuates cell toxicity. Proc Natl Acad Sci U S A. 2019;116:3712-3721 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 4d
Bagashev A, Sotillo E, Tang C, Black K, Perazzelli J, Seeholzer S, et al. CD19 Alterations Emerging after CD19-Directed Immunotherapy Cause Retention of the Misfolded Protein in the Endoplasmic Reticulum. Mol Cell Biol. 2018;38: pubmed publisher
  • western blot; human; loading ...; fig 5a
Merrill N, Schipper J, Karnes J, Kauffman A, Martin K, Mackeigan J. PI3K-C2? knockdown decreases autophagy and maturation of endocytic vesicles. PLoS ONE. 2017;12:e0184909 pubmed publisher
  • western blot; human; loading ...; fig s1
Yanatori I, Richardson D, Toyokuni S, Kishi F. The iron chaperone poly(rC)-binding protein 2 forms a metabolon with the heme oxygenase 1/cytochrome P450 reductase complex for heme catabolism and iron transfer. J Biol Chem. 2017;292:13205-13229 pubmed publisher
  • western blot; human; loading ...; fig 4
Huang B, Lin C, Wang C, Kao S. Upregulation of heat shock protein 70 and the differential protein expression induced by tumor necrosis factor-alpha enhances migration and inhibits apoptosis of hepatocellular carcinoma cell HepG2. Int J Med Sci. 2017;14:284-293 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig s2l
Lee C, Hanna A, Wang H, Dagnino Acosta A, Joshi A, Knoblauch M, et al. A chemical chaperone improves muscle function in mice with a RyR1 mutation. Nat Commun. 2017;8:14659 pubmed publisher
  • western blot; rat; loading ...; fig 1c
Chambers T, Santiesteban L, Gomez D, Chambers J. Sab mediates mitochondrial dysfunction involved in imatinib mesylate-induced cardiotoxicity. Toxicology. 2017;382:24-35 pubmed publisher
  • immunocytochemistry; mouse; 1:100; loading ...; fig s5a
Bagh M, Peng S, Chandra G, Zhang Z, Singh S, Pattabiraman N, et al. Misrouting of v-ATPase subunit V0a1 dysregulates lysosomal acidification in a neurodegenerative lysosomal storage disease model. Nat Commun. 2017;8:14612 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 5
Assadi G, Vesterlund L, Bonfiglio F, Mazzurana L, Cordeddu L, Schepis D, et al. Functional Analyses of the Crohn's Disease Risk Gene LACC1. PLoS ONE. 2016;11:e0168276 pubmed publisher
  • western blot; human; loading ...; fig 4a
Shahani N, Swarnkar S, Giovinazzo V, Morgenweck J, Bohn L, Scharager Tapia C, et al. RasGRP1 promotes amphetamine-induced motor behavior through a Rhes interaction network ("Rhesactome") in the striatum. Sci Signal. 2016;9:ra111 pubmed
  • western blot; human; fig 6a
Thura M, Al Aidaroos A, Yong W, Kono K, Gupta A, Lin Y, et al. PRL3-zumab, a first-in-class humanized antibody for cancer therapy. JCI Insight. 2016;1:e87607 pubmed publisher
  • immunocytochemistry; human; 1:100; fig 3e
Gallagher C, Walter P. Ceapins inhibit ATF6α signaling by selectively preventing transport of ATF6α to the Golgi apparatus during ER stress. elife. 2016;5: pubmed publisher
  • western blot; mouse; loading ...; fig 4a
Tamura Y, Matsunaga Y, Kitaoka Y, Hatta H. Effects of Heat Stress Treatment on Age-dependent Unfolded Protein Response in Different Types of Skeletal Muscle. J Gerontol A Biol Sci Med Sci. 2017;72:299-308 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 4
Ouimet M, Hennessy E, van Solingen C, Koelwyn G, Hussein M, Ramkhelawon B, et al. miRNA Targeting of Oxysterol-Binding Protein-Like 6 Regulates Cholesterol Trafficking and Efflux. Arterioscler Thromb Vasc Biol. 2016;36:942-951 pubmed publisher
  • western blot; human; loading ...; fig 1b
Paladino D, Yue P, Furuya H, Acoba J, Rosser C, Turkson J. A novel nuclear Src and p300 signaling axis controls migratory and invasive behavior in pancreatic cancer. Oncotarget. 2016;7:7253-67 pubmed publisher
  • western blot; human; 1:1000; fig 3
Patel M, Jacobson B, Ji Y, Drees J, Tang S, Xiong K, et al. Vesicular stomatitis virus expressing interferon-β is oncolytic and promotes antitumor immune responses in a syngeneic murine model of non-small cell lung cancer. Oncotarget. 2015;6:33165-77 pubmed publisher
  • western blot; human
Tan B, Mu R, Chang Y, Wang Y, Wu M, Tu H, et al. RNF4 negatively regulates NF-κB signaling by down-regulating TAB2. FEBS Lett. 2015;589:2850-8 pubmed publisher
  • western blot; human; fig 1
Lobb R, Becker M, Wen S, Wong C, Wiegmans A, Leimgruber A, et al. Optimized exosome isolation protocol for cell culture supernatant and human plasma. J Extracell Vesicles. 2015;4:27031 pubmed publisher
  • immunocytochemistry; human; fig 4
Wang J, Ma L, Tang X, Zhang X, Qiao Y, Shi Y, et al. Doxorubicin induces apoptosis by targeting Madcam1 and AKT and inhibiting protein translation initiation in hepatocellular carcinoma cells. Oncotarget. 2015;6:24075-91 pubmed
  • western blot; human; 1:1000; fig 6
Li H, Han L, Yang Z, Huang W, Zhang X, Gu Y, et al. Differential Proteomic Analysis of Syncytiotrophoblast Extracellular Vesicles from Early-Onset Severe Preeclampsia, using 8-Plex iTRAQ Labeling Coupled with 2D Nano LC-MS/MS. Cell Physiol Biochem. 2015;36:1116-30 pubmed publisher
  • western blot; human; fig s4
Min K, Liggett J, Silva G, Wu W, Wang R, Shen R, et al. NAG-1/GDF15 accumulates in the nucleus and modulates transcriptional regulation of the Smad pathway. Oncogene. 2016;35:377-88 pubmed publisher
  • immunohistochemistry - paraffin section; human; fig 2
Li G, Nguyen C, Ryckman B, Britt W, Kamil J. A viral regulator of glycoprotein complexes contributes to human cytomegalovirus cell tropism. Proc Natl Acad Sci U S A. 2015;112:4471-6 pubmed publisher
  • western blot; human
Wang Y, Tan B, Mu R, Chang Y, Wu M, Tu H, et al. Ubiquitin-associated domain-containing ubiquitin regulatory X (UBX) protein UBXN1 is a negative regulator of nuclear factor κB (NF-κB) signaling. J Biol Chem. 2015;290:10395-405 pubmed publisher
  • western blot; human; loading ...; fig 6b
Taura M, Kudo E, Kariya R, Goto H, Matsuda K, Hattori S, et al. COMMD1/Murr1 reinforces HIV-1 latent infection through IκB-α stabilization. J Virol. 2015;89:2643-58 pubmed publisher
  • western blot; human
Kemp M, Gaddameedhi S, Choi J, Hu J, Sancar A. DNA repair synthesis and ligation affect the processing of excised oligonucleotides generated by human nucleotide excision repair. J Biol Chem. 2014;289:26574-83 pubmed publisher
  • western blot; human
Termini C, Cotter M, Marjon K, Buranda T, Lidke K, Gillette J. The membrane scaffold CD82 regulates cell adhesion by altering α4 integrin stability and molecular density. Mol Biol Cell. 2014;25:1560-73 pubmed publisher
  • western blot; human; 1:500
Montague C, Fitzmaurice A, Hover B, Salazar N, Fey J. Screen for small molecules increasing the mitochondrial membrane potential. J Biomol Screen. 2014;19:387-98 pubmed publisher
Mrschtik M, O Prey J, Lao L, Long J, Beaumatin F, Strachan D, et al. DRAM-3 modulates autophagy and promotes cell survival in the absence of glucose. Cell Death Differ. 2015;22:1714-26 pubmed publisher
Bode C, Berlin M, Röstel F, Teichmann B, Gräler M. Evaluating sphingosine and its analogues as potential alternatives for aggressive lymphoma treatment. Cell Physiol Biochem. 2014;34:1686-700 pubmed publisher
Hergueta Redondo M, Sarrió D, Molina Crespo Ã, Megias D, Mota A, Rojo Sebastián A, et al. Gasdermin-B promotes invasion and metastasis in breast cancer cells. PLoS ONE. 2014;9:e90099 pubmed publisher
Firczuk M, Gabrysiak M, Barankiewicz J, Domagala A, Nowis D, Kujawa M, et al. GRP78-targeting subtilase cytotoxin sensitizes cancer cells to photodynamic therapy. Cell Death Dis. 2013;4:e741 pubmed publisher
Fabre B, Lambour T, Delobel J, Amalric F, Monsarrat B, Burlet Schiltz O, et al. Subcellular distribution and dynamics of active proteasome complexes unraveled by a workflow combining in vivo complex cross-linking and quantitative proteomics. Mol Cell Proteomics. 2013;12:687-99 pubmed publisher
Covy J, Waxman E, Giasson B. Characterization of cellular protective effects of ATP13A2/PARK9 expression and alterations resulting from pathogenic mutants. J Neurosci Res. 2012;90:2306-16 pubmed publisher
Tasseva G, Cole L, Vance J. N-Myc and SP regulate phosphatidylserine synthase-1 expression in brain and glial cells. J Biol Chem. 2011;286:1061-73 pubmed publisher
product information
SKU :
2679S
Product-Name :
Calnexin (C5C9) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, Mk
Applications :
Immunofluorescence (Immunocytochemistry)
Product-Category :
Protein Folding and Trafficking
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
90
Host :
Rabbit
Target :
Calnexin
Primary-Protein :
calnexin
Alt-Names :
CALX,CANX,CNX,Calnexin,FLJ26570,IP90,Major histocompatibility complex class I antigen-binding protein p88,p90
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.