product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
IKKβ (L570) Antibody
catalog :
2678
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, cow
application :
western blot, immunoprecipitation
more info or order :
Cell Signaling Technology product webpage
citations: 13
Published Application/Species/Sample/DilutionReference
  • immunoprecipitation; human; loading ...; fig 3e
Chuang H, Tsai C, Hsueh C, Tan T. GLK-IKKβ signaling induces dimerization and translocation of the AhR-RORγt complex in IL-17A induction and autoimmune disease. Sci Adv. 2018;4:eaat5401 pubmed publisher
  • western blot; human; loading ...; fig 1b
Sahu U, Choudhury A, Parvez S, Biswas S, Kar S. Induction of intestinal stemness and tumorigenicity by aberrant internalization of commensal non-pathogenic E. coli. Cell Death Dis. 2017;8:e2667 pubmed publisher
  • western blot; human; fig 4
Xie W, Zhang L, Jiao H, Guan L, Zha J, Li X, et al. Chaperone-mediated autophagy prevents apoptosis by degrading BBC3/PUMA. Autophagy. 2015;11:1623-35 pubmed publisher
  • western blot; rat
Bharti S, Rani N, Bhatia J, Arya D. 5-HT2B receptor blockade attenuates β-adrenergic receptor-stimulated myocardial remodeling in rats via inhibiting apoptosis: role of MAPKs and HSPs. Apoptosis. 2015;20:455-65 pubmed publisher
  • immunoprecipitation; human; 1:1000; loading ...; fig s2
  • western blot; human; 1:1000; loading ...; fig s2
Piao H, Yuan Y, Wang M, Sun Y, Liang H, Ma L. ?-catenin acts as a tumour suppressor in E-cadherin-negative basal-like breast cancer by inhibiting NF-?B signalling. Nat Cell Biol. 2014;16:245-54 pubmed publisher
  • western blot; human
Hast B, Cloer E, Goldfarb D, Li H, Siesser P, Yan F, et al. Cancer-derived mutations in KEAP1 impair NRF2 degradation but not ubiquitination. Cancer Res. 2014;74:808-17 pubmed publisher
  • western blot; human; 1:1000; fig 4a
Wu L, Shao L, An N, Wang J, Pazhanisamy S, Feng W, et al. IKK? regulates the repair of DNA double-strand breaks induced by ionizing radiation in MCF-7 breast cancer cells. PLoS ONE. 2011;6:e18447 pubmed publisher
Sui Y, Liu Z, Park S, Thatcher S, Zhu B, Fernandez J, et al. IKK? is a ?-catenin kinase that regulates mesenchymal stem cell differentiation. JCI Insight. 2018;3: pubmed publisher
Kim J, Noh E, Kim H, Kim M, Song H, Lee M, et al. Suppression of TPA-induced cancer cell invasion by Peucedanum japonicum Thunb. extract through the inhibition of PKCα/NF-κB-dependent MMP-9 expression in MCF-7 cells. Int J Mol Med. 2016;37:108-14 pubmed publisher
Sato M, Kuroda S, Mansjur K, Khaliunaa G, Nagata K, Horiuchi S, et al. Low-intensity pulsed ultrasound rescues insufficient salivary secretion in autoimmune sialadenitis. Arthritis Res Ther. 2015;17:278 pubmed publisher
Lavorgna A, Matsuoka M, Harhaj E. A critical role for IL-17RB signaling in HTLV-1 tax-induced NF-κB activation and T-cell transformation. PLoS Pathog. 2014;10:e1004418 pubmed publisher
Burns S, Plagnol V, Gutierrez B, Al Zahrani D, CURTIS J, Gaspar M, et al. Immunodeficiency and disseminated mycobacterial infection associated with homozygous nonsense mutation of IKK?. J Allergy Clin Immunol. 2014;134:215-8 pubmed publisher
Kenneth N, Mudie S, Naron S, Rocha S. TfR1 interacts with the IKK complex and is involved in IKK-NF-κB signalling. Biochem J. 2013;449:275-84 pubmed publisher
product information
SKU :
2678P
Product-Name :
IKKβ (L570) Antibody
Size :
40 ul
Price-(USD) :
123 USD
Species-x-Reactivity :
H, M, R, Hm, Mk, B, GP
Applications :
Immunoprecipitation
Product-Category :
Immunology and Inflammation
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
87
Host :
Rabbit
Target :
IKK-beta
Primary-Protein :
IKK-beta
Alt-Names :
FLJ40509,I-kappa-B kinase 2,I-kappa-B-kinase beta,IKBKB,IKK-B,IKK-beta,IKK2,IKKB,Inhibitor of nuclear factor kappa-B kinase subunit beta,MGC131801,NFKBIKB,Nuclear factor NF-kappa-B inhibitor kinase beta,inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.