product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
β-Catenin (L54E2) Mouse mAb (IF Preferred)
catalog :
2677
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
L54E2
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section
citations: 10
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 5B
Bakshi S, Taylor J, Strickson S, McCartney T, Cohen P. Identification of TBK1 complexes required for the phosphorylation of IRF3 and the production of interferon ?. Biochem J. 2017;474:1163-1174 pubmed publisher
  • immunocytochemistry; human; 1:200; fig 5f
Huang T, Alvarez A, Pangeni R, Horbinski C, Lu S, Kim S, et al. A regulatory circuit of miR-125b/miR-20b and Wnt signalling controls glioblastoma phenotypes through FZD6-modulated pathways. Nat Commun. 2016;7:12885 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:200; fig 9
Dianati E, Poiraud J, Weber Ouellette A, Plante I. Connexins, E-cadherin, Claudin-7 and ?-catenin transiently form junctional nexuses during the post-natal mammary gland development. Dev Biol. 2016;416:52-68 pubmed publisher
  • western blot; human; 1:1000; fig 7
Zhao L, Li S, Gan L, Li C, Qiu Z, Feng Y, et al. Paired box 5 is a frequently methylated lung cancer tumour suppressor gene interfering β-catenin signalling and GADD45G expression. J Cell Mol Med. 2016;20:842-54 pubmed publisher
  • immunohistochemistry; human; loading ...; fig 6b
Eiring A, Khorashad J, Anderson D, Yu F, Redwine H, Mason C, et al. β-Catenin is required for intrinsic but not extrinsic BCR-ABL1 kinase-independent resistance to tyrosine kinase inhibitors in chronic myeloid leukemia. Leukemia. 2015;29:2328-37 pubmed publisher
  • flow cytometry; mouse
McGuire D, Rowse A, Li H, Peng B, Sestero C, Cashman K, et al. CD5 enhances Th17-cell differentiation by regulating IFN-? response and ROR?t localization. Eur J Immunol. 2014;44:1137-42 pubmed publisher
Arasada R, Shilo K, Yamada T, Zhang J, Yano S, Ghanem R, et al. Notch3-dependent β-catenin signaling mediates EGFR TKI drug persistence in EGFR mutant NSCLC. Nat Commun. 2018;9:3198 pubmed publisher
Ndoye A, Budina Kolomets A, Kugel C, Webster M, Kaur A, Behera R, et al. ATG5 Mediates a Positive Feedback Loop between Wnt Signaling and Autophagy in Melanoma. Cancer Res. 2017;77:5873-5885 pubmed publisher
Francis K, Ton A, Xin Y, O Halloran P, Wassif C, Malik N, et al. Modeling Smith-Lemli-Opitz syndrome with induced pluripotent stem cells reveals a causal role for Wnt/β-catenin defects in neuronal cholesterol synthesis phenotypes. Nat Med. 2016;22:388-96 pubmed publisher
Wang M, Hada M, Huff J, Pluth J, Anderson J, O Neill P, et al. Heavy ions can enhance TGFβ mediated epithelial to mesenchymal transition. J Radiat Res. 2012;53:51-7 pubmed
product information
SKU :
2677S
Product-Name :
β-Catenin (L54E2) Mouse mAb (IF Preferred)
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, (M, R, Mk, Pg)
Applications :
Flow cytometry
Product-Category :
Developmental Biology
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
92
Host :
Mouse
Target :
Catenin-beta
Primary-Protein :
CTNNB1
Alt-Names :
Beta-catenin,CTNB1,CTNNB,CTNNB1,Catenin beta-1,DKFZp686D02253,FLJ25606,FLJ37923,catenin (cadherin-associated protein), beta 1, 88kDa
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.