| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; mouse; 1:1000; loading ...; fig 4c
| Haricharan S, Punturi N, Singh P, Holloway K, Anurag M, Schmelz J, et al. Loss of MutL Disrupts CHK2-Dependent Cell-Cycle Control through CDK4/6 to Promote Intrinsic Endocrine Therapy Resistance in Primary Breast Cancer. Cancer Discov. 2017;7:1168-1183 pubmed publisher |
- western blot; human; loading ...; fig 5c
| Ponath V, Kaina B. Death of Monocytes through Oxidative Burst of Macrophages and Neutrophils: Killing in Trans. PLoS ONE. 2017;12:e0170347 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 3
| Aksoy P, Meneses P. The Role of DCT in HPV16 Infection of HaCaTs. PLoS ONE. 2017;12:e0170158 pubmed publisher |
- western blot; human; loading ...; fig 1d
| Nagano T, Nakano M, Nakashima A, Onishi K, Yamao S, Enari M, et al. Identification of cellular senescence-specific genes by comparative transcriptomics. Sci Rep. 2016;6:31758 pubmed publisher |
- western blot; human; fig 2a
| Ray A, Blevins C, Wani G, Wani A. ATR- and ATM-Mediated DNA Damage Response Is Dependent on Excision Repair Assembly during G1 but Not in S Phase of Cell Cycle. PLoS ONE. 2016;11:e0159344 pubmed publisher |
| Morales J, Richard P, Patidar P, Motea E, Dang T, Manley J, et al. XRN2 Links Transcription Termination to DNA Damage and Replication Stress. PLoS Genet. 2016;12:e1006107 pubmed publisher |
- western blot; human; 1:1000; fig 2
| Bristol M, Wang X, Smith N, Son M, Evans M, Morgan I. DNA Damage Reduces the Quality, but Not the Quantity of Human Papillomavirus 16 E1 and E2 DNA Replication. Viruses. 2016;8: pubmed publisher |
- western blot; human; 1:3000; fig 8
| Kii I, Sumida Y, Goto T, Sonamoto R, Okuno Y, Yoshida S, et al. Selective inhibition of the kinase DYRK1A by targeting its folding process. Nat Commun. 2016;7:11391 pubmed publisher |
- western blot; human; fig 1a
| Kemp M, Sancar A. ATR Kinase Inhibition Protects Non-cycling Cells from the Lethal Effects of DNA Damage and Transcription Stress. J Biol Chem. 2016;291:9330-42 pubmed publisher |
- western blot; human; 1:1000; fig s6
| Franz A, Pirson P, Pilger D, Halder S, Achuthankutty D, Kashkar H, et al. Chromatin-associated degradation is defined by UBXN-3/FAF1 to safeguard DNA replication fork progression. Nat Commun. 2016;7:10612 pubmed publisher |
- western blot; human; fig s5
| Cristini A, Park J, Capranico G, Legube G, Favre G, Sordet O. DNA-PK triggers histone ubiquitination and signaling in response to DNA double-strand breaks produced during the repair of transcription-blocking topoisomerase I lesions. Nucleic Acids Res. 2016;44:1161-78 pubmed publisher |
- western blot; human; 1:1000; fig 1
| Ortega Atienza S, Wong V, Deloughery Z, Luczak M, Zhitkovich A. ATM and KAT5 safeguard replicating chromatin against formaldehyde damage. Nucleic Acids Res. 2016;44:198-209 pubmed publisher |
- western blot; human; fig 1
| Park S, Shim J, Park H, Eum D, Park M, Mi Yi J, et al. MacroH2A1 downregulation enhances the stem-like properties of bladder cancer cells by transactivation of Lin28B. Oncogene. 2016;35:1292-301 pubmed publisher |
- western blot; human; fig 1
| Hollingworth R, Skalka G, Stewart G, Hislop A, Blackbourn D, Grand R. Activation of DNA Damage Response Pathways during Lytic Replication of KSHV. Viruses. 2015;7:2908-27 pubmed publisher |
- western blot; human; fig 5
| Xu Y, Wu X, Her C. hMSH5 Facilitates the Repair of Camptothecin-induced Double-strand Breaks through an Interaction with FANCJ. J Biol Chem. 2015;290:18545-58 pubmed publisher |
- western blot; mouse; loading ...; fig 7a
| Ruan X, Zuo Q, Jia H, Chau J, Lin J, Ao J, et al. P53 deficiency-induced Smad1 upregulation suppresses tumorigenesis and causes chemoresistance in colorectal cancers. J Mol Cell Biol. 2015;7:105-18 pubmed publisher |
- western blot; human; loading ...; fig 4a
| Gao R, Liu Y, Silva Fernandes A, Fang X, Paulucci Holthauzen A, Chatterjee A, et al. Inactivation of PNKP by mutant ATXN3 triggers apoptosis by activating the DNA damage-response pathway in SCA3. PLoS Genet. 2015;11:e1004834 pubmed publisher |
| Sekimoto T, Oda T, Kurashima K, Hanaoka F, Yamashita T. Both high-fidelity replicative and low-fidelity Y-family polymerases are involved in DNA rereplication. Mol Cell Biol. 2015;35:699-715 pubmed publisher |
- western blot; human; loading ...; fig 4a
| Wei F, Ojo D, Lin X, Wong N, He L, Yan J, et al. BMI1 attenuates etoposide-induced G2/M checkpoints via reducing ATM activation. Oncogene. 2015;34:3063-75 pubmed publisher |
- western blot; human; fig 4
| Moskwa P, Zinn P, Choi Y, Shukla S, Fendler W, Chen C, et al. A functional screen identifies miRs that induce radioresistance in glioblastomas. Mol Cancer Res. 2014;12:1767-78 pubmed publisher |
- western blot; human; 1:1000; fig 4a
| Zhang P, Wei Y, Wang L, Debeb B, Yuan Y, Zhang J, et al. ATM-mediated stabilization of ZEB1 promotes DNA damage response and radioresistance through CHK1. Nat Cell Biol. 2014;16:864-75 pubmed publisher |
| Al Rakan M, Hendrayani S, Aboussekhra A. CHEK2 represses breast stromal fibroblasts and their paracrine tumor-promoting effects through suppressing SDF-1 and IL-6. BMC Cancer. 2016;16:575 pubmed publisher |
| Shamseddine A, Clarke C, Carroll B, Airola M, Mohammed S, Rella A, et al. P53-dependent upregulation of neutral sphingomyelinase-2: role in doxorubicin-induced growth arrest. Cell Death Dis. 2015;6:e1947 pubmed publisher |
| Boysen G, Barbieri C, Prandi D, Blattner M, Chae S, Dahija A, et al. SPOP mutation leads to genomic instability in prostate cancer. elife. 2015;4: pubmed publisher |
| Gemble S, Ahuja A, Buhagiar Labarchède G, Onclercq Delic R, Dairou J, Biard D, et al. Pyrimidine Pool Disequilibrium Induced by a Cytidine Deaminase Deficiency Inhibits PARP-1 Activity, Leading to the Under Replication of DNA. PLoS Genet. 2015;11:e1005384 pubmed publisher |
| Chen W, Ebelt N, Stracker T, Xhemalce B, Van Den Berg C, Miller K. ATM regulation of IL-8 links oxidative stress to cancer cell migration and invasion. elife. 2015;4: pubmed publisher |
| Jilg C, Ketscher A, Metzger E, Hummel B, Willmann D, Rüsseler V, et al. PRK1/PKN1 controls migration and metastasis of androgen-independent prostate cancer cells. Oncotarget. 2014;5:12646-64 pubmed |
| Zuazua Villar P, Rodriguez R, Gagou M, Eyers P, Meuth M. DNA replication stress in CHK1-depleted tumour cells triggers premature (S-phase) mitosis through inappropriate activation of Aurora kinase B. Cell Death Dis. 2014;5:e1253 pubmed publisher |
| Rajendran P, Kidane A, Yu T, Dashwood W, Bisson W, LOHR C, et al. HDAC turnover, CtIP acetylation and dysregulated DNA damage signaling in colon cancer cells treated with sulforaphane and related dietary isothiocyanates. Epigenetics. 2013;8:612-23 pubmed publisher |
| Floyd S, Pacold M, Huang Q, Clarke S, Lam F, Cannell I, et al. The bromodomain protein Brd4 insulates chromatin from DNA damage signalling. Nature. 2013;498:246-50 pubmed publisher |
| Li B, Shang Z, Yin J, Xu Q, Liu X, Wang Y, et al. PIG3 functions in DNA damage response through regulating DNA-PKcs homeostasis. Int J Biol Sci. 2013;9:425-34 pubmed publisher |
| Kouzine F, Gupta A, Baranello L, Wójtowicz D, Ben Aissa K, Liu J, et al. Transcription-dependent dynamic supercoiling is a short-range genomic force. Nat Struct Mol Biol. 2013;20:396-403 pubmed publisher |
| Niu R, Yoshida M, Ling F. Increases in mitochondrial DNA content and 4977-bp deletion upon ATM/Chk2 checkpoint activation in HeLa cells. PLoS ONE. 2012;7:e40572 pubmed publisher |
| Tseng H, Chuah Q, Yang P, Chen C, Chao J, Lin M, et al. Securin enhances the anti-cancer effects of 6-methoxy-3-(3',4',5'-trimethoxy-benzoyl)-1H-indole (BPR0L075) in human colorectal cancer cells. PLoS ONE. 2012;7:e36006 pubmed publisher |
| Wang Y, Liu Q, Liu Z, Li B, Sun Z, Zhou H, et al. Berberine, a genotoxic alkaloid, induces ATM-Chk1 mediated G2 arrest in prostate cancer cells. Mutat Res. 2012;734:20-9 pubmed publisher |
| Vadnais C, Davoudi S, Afshin M, Harada R, Dudley R, Clermont P, et al. CUX1 transcription factor is required for optimal ATM/ATR-mediated responses to DNA damage. Nucleic Acids Res. 2012;40:4483-95 pubmed publisher |
| Nikitin P, Yan C, Forte E, Bocedi A, Tourigny J, White R, et al. An ATM/Chk2-mediated DNA damage-responsive signaling pathway suppresses Epstein-Barr virus transformation of primary human B cells. Cell Host Microbe. 2010;8:510-22 pubmed publisher |
| Kadaja M, Isok Paas H, Laos T, Ustav E, Ustav M. Mechanism of genomic instability in cells infected with the high-risk human papillomaviruses. PLoS Pathog. 2009;5:e1000397 pubmed publisher |
