product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Stat4 (C46B10) Rabbit mAb
catalog :
2653
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
C46B10
reactivity :
human, mouse, rat
application :
western blot, immunoprecipitation, chromatin immunoprecipitation
more info or order :
Cell Signaling Technology product webpage
citations: 8
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 4a
Simonović N, Witalisz Siepracka A, Meissl K, Lassnig C, Reichart U, Kolbe T, et al. NK Cells Require Cell-Extrinsic and -Intrinsic TYK2 for Full Functionality in Tumor Surveillance and Antibacterial Immunity. J Immunol. 2019;202:1724-1734 pubmed publisher
  • western blot; human; loading ...; fig 4b
Penafuerte C, Feldhammer M, Mills J, Vinette V, Pike K, Hall A, et al. Downregulation of PTP1B and TC-PTP phosphatases potentiate dendritic cell-based immunotherapy through IL-12/IFN? signaling. Oncoimmunology. 2017;6:e1321185 pubmed publisher
Meyer zu Horste G, Przybylski D, Schramm M, Wang C, Schnell A, Lee Y, et al. Fas Promotes T Helper 17 Cell Differentiation and Inhibits T Helper 1 Cell Development by Binding and Sequestering Transcription Factor STAT1. Immunity. 2018;48:556-569.e7 pubmed publisher
Prchal Murphy M, Witalisz Siepracka A, Bednarik K, Putz E, Gotthardt D, Meissl K, et al. In vivo tumor surveillance by NK cells requires TYK2 but not TYK2 kinase activity. Oncoimmunology. 2015;4:e1047579 pubmed
Boivin N, Baillargeon J, Doss P, Roy A, Rangachari M. Interferon-β suppresses murine Th1 cell function in the absence of antigen-presenting cells. PLoS ONE. 2015;10:e0124802 pubmed publisher
Wachowicz K, Hermann Kleiter N, Meisel M, Siegmund K, Thuille N, Baier G. Protein kinase C θ regulates the phenotype of murine CD4+ Th17 cells. PLoS ONE. 2014;9:e96401 pubmed publisher
Putz E, Gotthardt D, Hoermann G, Csiszar A, Wirth S, Berger A, et al. CDK8-mediated STAT1-S727 phosphorylation restrains NK cell cytotoxicity and tumor surveillance. Cell Rep. 2013;4:437-44 pubmed publisher
Prchal Murphy M, Semper C, Lassnig C, Wallner B, Gausterer C, Teppner Klymiuk I, et al. TYK2 kinase activity is required for functional type I interferon responses in vivo. PLoS ONE. 2012;7:e39141 pubmed publisher
product information
SKU :
2653S
Product-Name :
Stat4 (C46B10) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R
Applications :
Chromatin Immunoprecipitation
Product-Category :
Immunology and Inflammation
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
81
Host :
Rabbit
Target :
Stat4
Primary-Protein :
STAT4
Alt-Names :
SLEB11,STAT4,Signal transducer and activator of transcription 4
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.