product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Skp2 (D3G5) XP® Rabbit mAb
catalog :
2652
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D3G5
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, western blot knockout validation
citations: 8
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; human; 1:1000; loading ...; fig 3i
Yao F, Zhou Z, Kim J, Hang Q, Xiao Z, Ton B, et al. SKP2- and OTUD1-regulated non-proteolytic ubiquitination of YAP promotes YAP nuclear localization and activity. Nat Commun. 2018;9:2269 pubmed publisher
  • immunocytochemistry; human; 1:1000; loading ...; fig s4f
  • western blot; human; 1:1000; loading ...; fig s4d
Li Y, Liu Y, Xu H, Jiang G, Van der Jeught K, Fang Y, et al. Heterozygous deletion of chromosome 17p renders prostate cancer vulnerable to inhibition of RNA polymerase II. Nat Commun. 2018;9:4394 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 7h
  • immunoprecipitation; human; loading ...; fig 3a
  • immunohistochemistry; human; 1:1000; loading ...; fig 6b
  • western blot; human; 1:1000; loading ...; fig 1b
Xu J, Zhou W, Yang F, Chen G, Li H, Zhao Y, et al. The β-TrCP-FBXW2-SKP2 axis regulates lung cancer cell growth with FBXW2 acting as a tumour suppressor. Nat Commun. 2017;8:14002 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 2c
Schlierf A, Altmann E, Quancard J, Jefferson A, Assenberg R, Renatus M, et al. Targeted inhibition of the COP9 signalosome for treatment of cancer. Nat Commun. 2016;7:13166 pubmed publisher
  • western blot; human; loading ...; fig 2a
Wang C, Guo S, Wang J, Yan X, Farrelly M, Zhang Y, et al. Reactivation of ERK and Akt confers resistance of mutant BRAF colon cancer cells to the HSP90 inhibitor AUY922. Oncotarget. 2016;7:49597-49610 pubmed publisher
  • western blot; human; fig 3b
Yu D, Makkar G, Dong T, Strickland D, Sarkar R, Monahan T. MARCKS Signaling Differentially Regulates Vascular Smooth Muscle and Endothelial Cell Proliferation through a KIS-, p27kip1- Dependent Mechanism. PLoS ONE. 2015;10:e0141397 pubmed publisher
  • western blot; human; 1:1000
Tanaka T, Iino M. Knockdown of Sec8 promotes cell-cycle arrest at G1/S phase by inducing p21 via control of FOXO proteins. FEBS J. 2014;281:1068-84 pubmed publisher
Wei W, Li L, Wang X, Yan L, Cao W, Zhan Z, et al. Overexpression of caudal type homeobox transcription factor 2 inhibits the growth of the MGC-803 human gastric cancer cell line in vivo. Mol Med Rep. 2015;12:905-12 pubmed publisher
product information
SKU :
2652P
Product-Name :
Skp2 (D3G5) XP® Rabbit mAb
Size :
40 ul
Price-(USD) :
135 USD
Species-x-Reactivity :
H, Mk
Applications :
Immunofluorescence (Immunocytochemistry)
Product-Category :
Ubiquitin and Ubiquitin-like proteins
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
48
Host :
Rabbit
Target :
Skp2
Primary-Protein :
SKP2
Alt-Names :
CDK2/cyclin A-associated protein p45,Cyclin-A/CDK2-associated protein p45,F-box protein Skp2,F-box/LRR-repeat protein 1,FBL1,FBXL1,FLB1,MGC1366,S-phase kinase-associated protein 2,S-phase kinase-associated protein 2 (p45),SKP2,cyclin A/CDK2-associated protein p45,p45skp2
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.