EGF Receptor (C74B9) Rabbit mAb | Cell Signaling Technology 2646 product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

EGF Receptor (C74B9) Rabbit mAb

catalog :

2646

clonality :

monoclonal

host :

rabbit

conjugate :

nonconjugated

clone name :

C74B9

reactivity :

hamsters, human, mouse, rat

application :

western blot, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section

more info or order :

Cell Signaling Technology product webpage

citations: 20

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 7f	Liu S, Liu H, Johnston A, Hanna Addams S, Reynoso E, Xiang Y, et al. MLKL forms disulfide bond-dependent amyloid-like polymers to induce necroptosis. Proc Natl Acad Sci U S A. 2017;114:E7450-E7459 pubmed publisher
western blot; mouse; loading ...; fig 1f	Bi P, Ramirez Martinez A, Li H, Cannavino J, McAnally J, Shelton J, et al. Control of muscle formation by the fusogenic micropeptide myomixer. Science. 2017;356:323-327 pubmed publisher
western blot; human; loading ...; fig 1a	Grassi M, Palma C, Thomé C, Lanfredi G, Poersch A, Faça V. Proteomic analysis of ovarian cancer cells during epithelial-mesenchymal transition (EMT) induced by epidermal growth factor (EGF) reveals mechanisms of cell cycle control. J Proteomics. 2017;151:2-11 pubmed publisher
western blot; human; 1:1000; loading ...; fig 3f	Jiang M, Qiu J, Zhang L, Lu D, Long M, Chen L, et al. Changes in tension regulates proliferation and migration of fibroblasts by remodeling expression of ECM proteins. Exp Ther Med. 2016;12:1542-1550 pubmed
western blot; human	Yoo J, Kim T, Kong S, Lee J, Choi W, Kim K, et al. Role of Mig-6 in hepatic glucose metabolism. J Diabetes. 2016;8:86-97 pubmed publisher
western blot; mouse; fig 4	Nikonova A, Deneka A, Eckman L, Kopp M, Hensley H, Egleston B, et al. Opposing Effects of Inhibitors of Aurora-A and EGFR in Autosomal-Dominant Polycystic Kidney Disease. Front Oncol. 2015;5:228 pubmed publisher
immunohistochemistry - paraffin section; human; 1:50; fig 4 western blot; human; fig 4	Donzelli S, Mori F, Bellissimo T, Sacconi A, Casini B, Frixa T, et al. Epigenetic silencing of miR-145-5p contributes to brain metastasis. Oncotarget. 2015;6:35183-201 pubmed publisher
western blot; hamsters; loading ...; fig 7a	Liu Z, Leng E, Gunasekaran K, Pentony M, Shen M, Howard M, et al. A novel antibody engineering strategy for making monovalent bispecific heterodimeric IgG antibodies by electrostatic steering mechanism. J Biol Chem. 2015;290:7535-62 pubmed publisher
western blot; mouse	Smithline Z, Nikonova A, Hensley H, Cai K, Egleston B, Proia D, et al. Inhibiting heat shock protein 90 (HSP90) limits the formation of liver cysts induced by conditional deletion of Pkd1 in mice. PLoS ONE. 2014;9:e114403 pubmed publisher
western blot; human	Holland W, Chinn D, Lara P, Gandara D, Mack P. Effects of AKT inhibition on HGF-mediated erlotinib resistance in non-small cell lung cancer cell lines. J Cancer Res Clin Oncol. 2015;141:615-26 pubmed publisher
western blot; human; fig 1c	Zhang L, Castanaro C, Luan B, Yang K, Fan L, Fairhurst J, et al. ERBB3/HER2 signaling promotes resistance to EGFR blockade in head and neck and colorectal cancer models. Mol Cancer Ther. 2014;13:1345-55 pubmed publisher
immunocytochemistry; human; fig 3a	Yamashita M, Chattopadhyay S, Fensterl V, Saikia P, Wetzel J, Sen G. Epidermal growth factor receptor is essential for Toll-like receptor 3 signaling. Sci Signal. 2012;5:ra50 pubmed publisher
	Veleeparambil M, Poddar D, Abdulkhalek S, Kessler P, Yamashita M, Chattopadhyay S, et al. Constitutively Bound EGFR-Mediated Tyrosine Phosphorylation of TLR9 Is Required for Its Ability To Signal. J Immunol. 2018;200:2809-2818 pubmed publisher
	Daly C, Castanaro C, Zhang W, Zhang Q, Wei Y, Ni M, et al. FGFR3-TACC3 fusion proteins act as naturally occurring drivers of tumor resistance by functionally substituting for EGFR/ERK signaling. Oncogene. 2017;36:471-481 pubmed publisher
	Steinway S, Dang H, You H, Rountree C, Ding W. The EGFR/ErbB3 Pathway Acts as a Compensatory Survival Mechanism upon c-Met Inhibition in Human c-Met+ Hepatocellular Carcinoma. PLoS ONE. 2015;10:e0128159 pubmed publisher
	Howes A, Richardson R, Finlay D, Vuori K. 3-Dimensional culture systems for anti-cancer compound profiling and high-throughput screening reveal increases in EGFR inhibitor-mediated cytotoxicity compared to monolayer culture systems. PLoS ONE. 2014;9:e108283 pubmed publisher
	Salazar N, MuÃ±oz D, Kallifatidis G, Singh R, JordÃ M, Lokeshwar B. The chemokine receptor CXCR7 interacts with EGFR to promote breast cancer cell proliferation. Mol Cancer. 2014;13:198 pubmed publisher
	Arts M, Baron M, Chokr N, Fritzler M, Servant M. Systemic sclerosis immunoglobulin induces growth and a pro-fibrotic state in vascular smooth muscle cells through the epidermal growth factor receptor. PLoS ONE. 2014;9:e100035 pubmed publisher
	Van Kanegan M, He D, Dunn D, Yang P, Newman R, West A, et al. BDNF mediates neuroprotection against oxygen-glucose deprivation by the cardiac glycoside oleandrin. J Neurosci. 2014;34:963-8 pubmed publisher
	Liu L, Shao X, Gao W, Zhang Z, Liu P, Wang R, et al. MicroRNA-133b inhibits the growth of non-small-cell lung cancer by targeting the epidermal growth factor receptor. FEBS J. 2012;279:3800-12 pubmed publisher

product information

SKU :

2646S

Product-Name :

EGF Receptor (C74B9) Rabbit mAb

Size :

100 ul

Price-(USD) :

235 USD

Species-x-Reactivity :

H, M, R, Mk

Applications :

Immunoprecipitation

Product-Category :

RTK

Shipping-Temp :

AMBIENT

Storage-Temp :

-20°C

Product-Type :

Monoclonal Antibody

MW :

175 kDa

Host :

Rabbit

Target :

EGFR

Primary-Protein :

EGFR

Alt-Names :

EGFR,ERBB,ERBB1,Epidermal growth factor receptor,HER1,PIG61,Proto-oncogene c-ErbB-1,Receptor tyrosine-protein kinase erbB-1,avian erythroblastic leukemia viral (v-erb-b) oncogene homolog,cell growth inhibiting protein 40,cell proliferation-inducing protein 61,epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian),mENA

more info or order :

Cell Signaling Technology product webpage