product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
GLI1 (L42B10) Mouse mAb
catalog :
2643S
quantity :
100 ul
price :
235 USD
clonality :
monoclonal
host :
mouse
reactivity :
human, mouse
application :
western blot, immunoprecipitation
more info or order :
Cell Signaling Technology product webpage
citations: 8
Published Application/Species/DilutionReference
  • western blot; mouse; fig 3
Chong Y, Mann R, Zhao C, Kato M, Beachy P. Bifurcating action of Smoothened in Hedgehog signaling is mediated by Dlg5. Genes Dev. 2015;29:262-76 pubmed publisher
  • western blot; human; fig 4
Lee S, Litan A, Li Z, Graves B, Lindsey S, Barwe S, et al. Na,K-ATPase β1-subunit is a target of sonic hedgehog signaling and enhances medulloblastoma tumorigenicity. Mol Cancer. 2015;14:159 pubmed publisher
  • western blot; mouse; fig 3
Shi X, Zhan X, Wu J. A positive feedback loop between Gli1 and tyrosine kinase Hck amplifies shh signaling activities in medulloblastoma. Oncogenesis. 2015;4:e176 pubmed publisher
  • western blot; human
Matsumoto T, Tabata K, Suzuki T. The GANT61, a GLI inhibitor, induces caspase-independent apoptosis of SK-N-LO cells. Biol Pharm Bull. 2014;37:633-41 pubmed
  • western blot; mouse; fig 6
Shi X, Zhang Z, Zhan X, Cao M, Satoh T, Akira S, et al. An epigenetic switch induced by Shh signalling regulates gene activation during development and medulloblastoma growth. Nat Commun. 2014;5:5425 pubmed publisher
  • western blot; mouse
Barakat M, Humke E, Scott M. Kif3a is necessary for initiation and maintenance of medulloblastoma. Carcinogenesis. 2013;34:1382-92 pubmed publisher
Carbe C, Cheng L, Addya S, Gold J, Gao E, Koch W, et al. Gi proteins mediate activation of the canonical hedgehog pathway in the myocardium. Am J Physiol Heart Circ Physiol. 2014;307:H66-72 pubmed publisher
Beauchamp E, Ringer L, Bulut G, Sajwan K, Hall M, Lee Y, et al. Arsenic trioxide inhibits human cancer cell growth and tumor development in mice by blocking Hedgehog/GLI pathway. J Clin Invest. 2011;121:148-60 pubmed publisher
product information
SKU :
2643S
Product-Name :
GLI1 (L42B10) Mouse mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H
Applications :
Immunoprecipitation
Product-Category :
Developmental Biology
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
160
Host :
Mouse
Target :
GLI1
Primary-Protein :
GLI1
Alt-Names :
GLI,GLI family zinc finger 1,GLI1,Glioma-associated oncogene,Oncogene GLI,Zinc finger protein GLI1,glioma-associated oncogene family zinc finger 1,glioma-associated oncogene homolog 1 (zinc finger protein)
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.