product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-PRAS40 (Thr246) Antibody
catalog :
2640
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
antigen modification :
phosphorylated
reactivity :
human, mouse, rat
application :
western blot
citations: 5
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; fig 2
Liu D, Bordicchia M, Zhang C, Fang H, Wei W, Li J, et al. Activation of mTORC1 is essential for ?-adrenergic stimulation of adipose browning. J Clin Invest. 2016;126:1704-16 pubmed publisher
  • western blot; human; fig 3
Agarwal S, Bell C, Taylor S, Moran R. p53 Deletion or Hotspot Mutations Enhance mTORC1 Activity by Altering Lysosomal Dynamics of TSC2 and Rheb. Mol Cancer Res. 2016;14:66-77 pubmed publisher
  • western blot; human
Samse K, Emathinger J, Hariharan N, Quijada P, Ilves K, Völkers M, et al. Functional Effect of Pim1 Depends upon Intracellular Localization in Human Cardiac Progenitor Cells. J Biol Chem. 2015;290:13935-47 pubmed publisher
  • western blot; human
Lu J, Zavorotinskaya T, Dai Y, Niu X, Castillo J, Sim J, et al. Pim2 is required for maintaining multiple myeloma cell growth through modulating TSC2 phosphorylation. Blood. 2013;122:1610-20 pubmed publisher
Roca H, Varsos Z, Pienta K. CCL2 is a negative regulator of AMP-activated protein kinase to sustain mTOR complex-1 activation, survivin expression, and cell survival in human prostate cancer PC3 cells. Neoplasia. 2009;11:1309-17 pubmed
product information
SKU :
2640S
Product-Name :
Phospho-PRAS40 (Thr246) Antibody
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Western blot
Product-Category :
PI3K / Akt Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
40
Host :
Rabbit
Target :
PRAS40 (Thr246) phosphate
Primary-Protein :
PRAS40
Alt-Names :
AKT1S1,proline-rich AKT1 substrate 1
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.