| Published Application/Species/Dilution | Reference |
|---|
- immunohistochemistry (knockdown validation); human; fig 1
- western blot (knockdown validation); human; fig 1
| Kobayashi K, Araya J, Minagawa S, Hara H, Saito N, Kadota T, et al. Involvement of PARK2-Mediated Mitophagy in Idiopathic Pulmonary Fibrosis Pathogenesis. J Immunol. 2016;: pubmed |
- western blot (knockdown validation); human; fig 2
| Zhao F, Huang W, Zhang Z, Mao L, Han Y, Yan J, et al. Triptolide induces protective autophagy through activation of the CaMKKβ-AMPK signaling pathway in prostate cancer cells. Oncotarget. 2016;7:5366-82 pubmed publisher |
- western blot (knockdown validation); rat; 1:1000; fig 8
- western blot; mouse; 1:1000; fig 6
| Lesmana R, Sinha R, Singh B, Zhou J, Ohba K, Wu Y, et al. Thyroid Hormone Stimulation of Autophagy Is Essential for Mitochondrial Biogenesis and Activity in Skeletal Muscle. Endocrinology. 2016;157:23-38 pubmed publisher |
- western blot (knockdown validation); human; fig 4
| Yen C, Chiang W, Liu S, Lin C, Liao K, Lin C, et al. Impacts of autophagy-inducing ingredient of areca nut on tumor cells. PLoS ONE. 2015;10:e0128011 pubmed publisher |
- western blot (knockdown validation); human; fig 3
| Garcia-Cano J, Ambroise G, Pascual-Serra R, Carrión M, Serrano-Oviedo L, Ortega-Muelas M, et al. Exploiting the potential of autophagy in cisplatin therapy: A new strategy to overcome resistance. Oncotarget. 2015;6:15551-65 pubmed |
- western blot (knockdown validation); human; fig 3
| Lau H, Ramanujulu P, Guo D, Yang T, Wirawan M, Casey P, et al. An improved isoprenylcysteine carboxylmethyltransferase inhibitor induces cancer cell death and attenuates tumor growth in vivo. Cancer Biol Ther. 2014;15:1280-91 pubmed publisher |
- western blot; mouse; 1:1000; fig 8
| Velázquez R, Shaw D, Caccamo A, Oddo S. Pim1 inhibition as a novel therapeutic strategy for Alzheimer's disease. Mol Neurodegener. 2016;11:52 pubmed publisher |
- western blot; rat; 1:600; fig 2
| Gui L, Liu B, Lv G. Hypoxia induces autophagy in cardiomyocytes via a hypoxia-inducible factor 1-dependent mechanism. Exp Ther Med. 2016;11:2233-2239 pubmed |
- western blot; human; fig 4
| Xiao L, Shi X, Zhang Y, Zhu Y, Zhu L, Tian W, et al. YAP induces cisplatin resistance through activation of autophagy in human ovarian carcinoma cells. Onco Targets Ther. 2016;9:1105-14 pubmed publisher |
- western blot; human; fig 2
| Guan J, Zhang X, Sun W, Qi L, Wu J, Qin Z. DRAM1 regulates apoptosis through increasing protein levels and lysosomal localization of BAX. Cell Death Dis. 2015;6:e1624 pubmed publisher |
| Cavieres V, Gonzalez A, Muñoz V, Yefi C, Bustamante H, Barraza R, et al. Tetrahydrohyperforin Inhibits the Proteolytic Processing of Amyloid Precursor Protein and Enhances Its Degradation by Atg5-Dependent Autophagy. PLoS ONE. 2015;10:e0136313 pubmed publisher |
- other; mouse; 1:500; fig s1
| Chiang C, Uzoma I, Lane D, Memisevic V, Alem F, Yao K, et al. A reverse-phase protein microarray-based screen identifies host signaling dynamics upon Burkholderia spp. infection. Front Microbiol. 2015;6:683 pubmed publisher |
- western blot; human; 1:1000
| Zanotto-Filho A, Braganhol E, Klafke K, Figueiró F, Terra S, Paludo F, et al. Autophagy inhibition improves the efficacy of curcumin/temozolomide combination therapy in glioblastomas. Cancer Lett. 2015;358:220-31 pubmed publisher |
- western blot; human; fig 3
| Eriksen A, Torgersen M, Holm K, Abrahamsen G, Spurkland A, Moskaug J, et al. Retinoic acid-induced IgG production in TLR-activated human primary B cells involves ULK1-mediated autophagy. Autophagy. 2015;11:460-71 pubmed publisher |
- western blot; mouse; fig 3e
| Xie C, Wei D, Zhao L, Marchetto S, Mei L, Borg J, et al. Erbin is a novel substrate of the Sag-βTrCP E3 ligase that regulates KrasG12D-induced skin tumorigenesis. J Cell Biol. 2015;209:721-37 pubmed publisher |
- western blot; human; 1:1000; fig 4
| Dowdle W, Nyfeler B, Nagel J, Elling R, Liu S, Triantafellow E, et al. Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo. Nat Cell Biol. 2014;16:1069-79 pubmed publisher |
- western blot; human; 1:1000
| Mancias J, Wang X, Gygi S, Harper J, Kimmelman A. Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy. Nature. 2014;509:105-9 pubmed publisher |
- western blot; human; 1:1,000
| Xia M, Gonzalez P, Li C, Meng G, Jiang A, Wang H, et al. Mitophagy enhances oncolytic measles virus replication by mitigating DDX58/RIG-I-like receptor signaling. J Virol. 2014;88:5152-64 pubmed publisher |
| Chang P, Wang T, Chang Y, Chu C, Lee C, Hsu H, et al. Autophagy pathway is required for IL-6 induced neuroendocrine differentiation and chemoresistance of prostate cancer LNCaP cells. PLoS ONE. 2014;9:e88556 pubmed publisher |
| Xu L, Long Z, Peng F, Liu Y, Xu J, Wang C, et al. Aurora kinase a suppresses metabolic stress-induced autophagic cell death by activating mTOR signaling in breast cancer cells. Oncotarget. 2014;5:7498-511 pubmed |
- western blot; human; 1:1000
| Giansanti V, Rodriguez G, Savoldelli M, Gioia R, Forlino A, Mazzini G, et al. Characterization of stress response in human retinal epithelial cells. J Cell Mol Med. 2013;17:103-15 pubmed publisher |
| Banduseela V, Chen Y, Kultima H, Norman H, Aare S, Radell P, et al. Impaired autophagy, chaperone expression, and protein synthesis in response to critical illness interventions in porcine skeletal muscle. Physiol Genomics. 2013;45:477-86 pubmed publisher |
- western blot; human; 1:1000
| Bauckman K, Haller E, Flores I, Nanjundan M. Iron modulates cell survival in a Ras- and MAPK-dependent manner in ovarian cells. Cell Death Dis. 2013;4:e592 pubmed publisher |
| Liang S, Figtree G, Aiqun M, Ping Z. GAPDH-knockdown reduce rotenone-induced H9C2 cells death via autophagy and anti-oxidative stress pathway. Toxicol Lett. 2015;234:162-71 pubmed publisher |
| Wei M, Chen M, Chen K, Lou P, Lin S, Hung S, et al. Autophagy promotes resistance to photodynamic therapy-induced apoptosis selectively in colorectal cancer stem-like cells. Autophagy. 2014;10:1179-92 pubmed publisher |
| Gutierrez E, Richardson D, Jansson P. The anticancer agent di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT) overcomes prosurvival autophagy by two mechanisms: persistent induction of autophagosome synthesis and impairment of lysosomal integrity. J Biol Chem. 2014;289:33568-89 pubmed publisher |
| Leung T, Rajendran R, Singh S, Garva R, Krstic-Demonacos M, Demonacos C. Cytochrome P450 2E1 (CYP2E1) regulates the response to oxidative stress and migration of breast cancer cells. Breast Cancer Res. 2013;15:R107 pubmed |
| Le Fourn V, Park S, Jang I, Gaplovska-Kysela K, Guhl B, Lee Y, et al. Large protein complexes retained in the ER are dislocated by non-COPII vesicles and degraded by selective autophagy. Cell Mol Life Sci. 2013;70:1985-2002 pubmed publisher |
| Yang J, Takahashi Y, Cheng E, Liu J, Terranova P, Zhao B, et al. GSK-3beta promotes cell survival by modulating Bif-1-dependent autophagy and cell death. J Cell Sci. 2010;123:861-70 pubmed publisher |
| Bommareddy A, Hahm E, Xiao D, Powolny A, Fisher A, Jiang Y, et al. Atg5 regulates phenethyl isothiocyanate-induced autophagic and apoptotic cell death in human prostate cancer cells. Cancer Res. 2009;69:3704-12 pubmed publisher |
| Han W, Pan H, Chen Y, Sun J, Wang Y, Li J, et al. EGFR tyrosine kinase inhibitors activate autophagy as a cytoprotective response in human lung cancer cells. PLoS ONE. 2011;6:e18691 pubmed publisher |
| Lock R, Roy S, Kenific C, Su J, Salas E, Ronen S, et al. Autophagy facilitates glycolysis during Ras-mediated oncogenic transformation. Mol Biol Cell. 2011;22:165-78 pubmed publisher |
| Zhou W, Deng R, Zhang X, Feng G, Gu L, Zhu X. G-quadruplex ligand SYUIQ-5 induces autophagy by telomere damage and TRF2 delocalization in cancer cells. Mol Cancer Ther. 2009;8:3203-13 pubmed publisher |
