product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Jagged1 (28H8) Rabbit mAb
catalog :
2620
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
28H8
reactivity :
human, mouse, brown rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 27
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 1a
Travisano S, Oliveira V, Prados B, Grego Bessa J, Piñeiro Sabarís R, Bou V, et al. Coronary arterial development is regulated by a Dll4-Jag1-EphrinB2 signaling cascade. elife. 2019;8: pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 6a
Lawlor K, Zappia L, Lefevre J, Park J, Hamilton N, Oshlack A, et al. Nephron progenitor commitment is a stochastic process influenced by cell migration. elife. 2019;8: pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig f1s3b
Nandagopal N, Santat L, Elowitz M. Cis-activation in the Notch signaling pathway. elife. 2019;8: pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:150; loading ...; fig 5c
Eley L, Alqahtani A, MacGrogan D, Richardson R, Murphy L, Salguero Jimenez A, et al. A novel source of arterial valve cells linked to bicuspid aortic valve without raphe in mice. elife. 2018;7: pubmed publisher
  • western blot; human; loading ...; fig 3e, 5b
Jin L, Vu T, Yuan G, Datta P. STRAP Promotes Stemness of Human Colorectal Cancer via Epigenetic Regulation of the NOTCH Pathway. Cancer Res. 2017;77:5464-5478 pubmed publisher
  • immunoprecipitation; human; fig s2a
  • western blot; human; fig s2a
  • western blot; mouse; loading ...; fig 1c
Antfolk D, Sjöqvist M, Cheng F, Isoniemi K, Duran C, Rivero Muller A, et al. Selective regulation of Notch ligands during angiogenesis is mediated by vimentin. Proc Natl Acad Sci U S A. 2017;114:E4574-E4581 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig s9a
  • western blot; mouse; loading ...; fig 1a
Kim W, Khan S, Gvozdenovic Jeremic J, Kim Y, Dahlman J, Kim H, et al. Hippo signaling interactions with Wnt/?-catenin and Notch signaling repress liver tumorigenesis. J Clin Invest. 2017;127:137-152 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:50; loading ...; fig 5e
  • western blot; mouse; fig 5c
Sizemore G, Balakrishnan S, Hammer A, Thies K, Trimboli A, Wallace J, et al. Stromal PTEN inhibits the expansion of mammary epithelial stem cells through Jagged-1. Oncogene. 2017;36:2297-2308 pubmed publisher
  • immunocytochemistry; human; fig 1e
  • western blot; human; fig 4e
Li S, Hu H, He Z, Liang D, Sun R, Lan K. Fine-Tuning of the Kaposi's Sarcoma-Associated Herpesvirus Life Cycle in Neighboring Cells through the RTA-JAG1-Notch Pathway. PLoS Pathog. 2016;12:e1005900 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:1000; loading ...
Kuzmanov U, Guo H, Buchsbaum D, Cosme J, Abbasi C, Isserlin R, et al. Global phosphoproteomic profiling reveals perturbed signaling in a mouse model of dilated cardiomyopathy. Proc Natl Acad Sci U S A. 2016;113:12592-12597 pubmed
  • western blot; human; fig 6d
Zhang P, He D, Chen Z, Pan Q, Du F, Zang X, et al. Chemotherapy enhances tumor vascularization via Notch signaling-mediated formation of tumor-derived endothelium in breast cancer. Biochem Pharmacol. 2016;118:18-30 pubmed publisher
  • western blot; human; loading ...; fig 6a
Xiao S, Chang R, Yang M, Lei X, Liu X, Gao W, et al. Actin-like 6A predicts poor prognosis of hepatocellular carcinoma and promotes metastasis and epithelial-mesenchymal transition. Hepatology. 2016;63:1256-71 pubmed publisher
  • western blot; human; fig 1
Dong X, Lin Q, Aihara A, Li Y, Huang C, Chung W, et al. Aspartate β-Hydroxylase expression promotes a malignant pancreatic cellular phenotype. Oncotarget. 2015;6:1231-48 pubmed
  • western blot; mouse; 1:800; fig 4
Katz Y, Li F, Lambert N, Sokol E, Tam W, Cheng A, et al. Musashi proteins are post-transcriptional regulators of the epithelial-luminal cell state. elife. 2014;3:e03915 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 4
Reginensi A, Scott R, Gregorieff A, Bagherie Lachidan M, Chung C, Lim D, et al. Yap- and Cdc42-dependent nephrogenesis and morphogenesis during mouse kidney development. PLoS Genet. 2013;9:e1003380 pubmed publisher
Guixà González R, Albasanz J, Rodríguez Espigares I, Pastor M, Sanz F, Marti Solano M, et al. Membrane cholesterol access into a G-protein-coupled receptor. Nat Commun. 2017;8:14505 pubmed publisher
Poulos M, Ramalingam P, Gutkin M, Kleppe M, Ginsberg M, Crowley M, et al. Endothelial-specific inhibition of NF-κB enhances functional haematopoiesis. Nat Commun. 2016;7:13829 pubmed publisher
Marschallinger J, Schäffner I, Klein B, Gelfert R, Rivera F, Illes S, et al. Structural and functional rejuvenation of the aged brain by an approved anti-asthmatic drug. Nat Commun. 2015;6:8466 pubmed publisher
Bagherie Lachidan M, Reginensi A, Pan Q, Zaveri H, Scott D, Blencowe B, et al. Stromal Fat4 acts non-autonomously with Dchs1/2 to restrict the nephron progenitor pool. Development. 2015;142:2564-73 pubmed publisher
Ottone C, Krusche B, Whitby A, Clements M, Quadrato G, Pitulescu M, et al. Direct cell-cell contact with the vascular niche maintains quiescent neural stem cells. Nat Cell Biol. 2014;16:1045-56 pubmed publisher
Fujiki K, Inamura H, Matsuoka M. Detrimental effects of Notch1 signaling activated by cadmium in renal proximal tubular epithelial cells. Cell Death Dis. 2014;5:e1378 pubmed publisher
De Salvo M, Raimondi L, Vella S, Adesso L, Ciarapica R, Verginelli F, et al. Hyper-activation of Notch3 amplifies the proliferative potential of rhabdomyosarcoma cells. PLoS ONE. 2014;9:e96238 pubmed publisher
Fiaschetti G, Schroeder C, Castelletti D, Arcaro A, Westermann F, Baumgartner M, et al. NOTCH ligands JAG1 and JAG2 as critical pro-survival factors in childhood medulloblastoma. Acta Neuropathol Commun. 2014;2:39 pubmed publisher
Morizane R, Fujii S, Monkawa T, Hiratsuka K, Yamaguchi S, Homma K, et al. miR-34c attenuates epithelial-mesenchymal transition and kidney fibrosis with ureteral obstruction. Sci Rep. 2014;4:4578 pubmed publisher
Liu M, Siu M, Liu S, Yam J, Ngan H, Chan D. Epigenetic silencing of microRNA-199b-5p is associated with acquired chemoresistance via activation of JAG1-Notch1 signaling in ovarian cancer. Oncotarget. 2014;5:944-58 pubmed
Myers M, Manning H, Coffey R, Liebler D. Protein expression signatures for inhibition of epidermal growth factor receptor-mediated signaling. Mol Cell Proteomics. 2012;11:M111.015222 pubmed publisher
Ghosh S, Paez Cortez J, Boppidi K, Vasconcelos M, Roy M, CARDOSO W, et al. Activation dynamics and signaling properties of Notch3 receptor in the developing pulmonary artery. J Biol Chem. 2011;286:22678-87 pubmed publisher
product information
SKU :
2620S
Product-Name :
Jagged1 (28H8) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, (R)
Applications :
Immunoprecipitation
Product-Category :
Developmental Biology
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
180
Host :
Rabbit
Target :
Jagged1
Primary-Protein :
JAG1
Alt-Names :
AGS,AHD,AWS,CD339,JAG1,JAGL1,Jagged1,MGC104644,Protein jagged-1,hJ1,jagged 1 (Alagille syndrome)
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.