product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-PAK1 (Thr423)/PAK2 (Thr402) Antibody
catalog :
2601S
quantity :
100 ul
price :
274 USD
clonality :
polyclonal
host :
rabbit
antigen modification :
phosphorylated
reactivity :
human, mouse
application :
western blot, immunohistochemistry - paraffin section
more info or order :
Cell Signaling Technology product webpage
citations: 9
Published Application/Species/DilutionReference
  • western blot; human; fig 5
D'Hulst G, Sylow L, Hespel P, Deldicque L. Acute systemic insulin intolerance does not alter the response of the Akt/GSK-3 pathway to environmental hypoxia in human skeletal muscle. Eur J Appl Physiol. 2015;115:1219-31 pubmed publisher
  • immunohistochemistry - paraffin section; human
  • western blot; human; 1:1000
Mortazavi F, Lu J, Phan R, Lewis M, Trinidad K, Aljilani A, et al. Significance of KRAS/PAK1/Crk pathway in non-small cell lung cancer oncogenesis. BMC Cancer. 2015;15:381 pubmed publisher
  • western blot; human; fig 2
  • western blot; mouse; fig 7
Yu D, Makkar G, Strickland D, Blanpied T, Stumpo D, Blackshear P, et al. Myristoylated Alanine-Rich Protein Kinase Substrate (MARCKS) Regulates Small GTPase Rac1 and Cdc42 Activity and Is a Critical Mediator of Vascular Smooth Muscle Cell Migration in Intimal Hyperplasia Formation. J Am Heart Assoc. 2015;4:e002255 pubmed publisher
  • western blot; mouse; 1:1000
Fowler S, Chiang A, Savjani R, Larson M, Sherman M, Schuler D, et al. Genetic modulation of soluble Aβ rescues cognitive and synaptic impairment in a mouse model of Alzheimer's disease. J Neurosci. 2014;34:7871-85 pubmed publisher
  • western blot; human; fig 4
Riaz A, Zeller K, Johansson S. Receptor-specific mechanisms regulate phosphorylation of AKT at Ser473: role of RICTOR in β1 integrin-mediated cell survival. PLoS ONE. 2012;7:e32081 pubmed publisher
Wang X, Cahill M, Werner C, Christoffel D, Golden S, Xie Z, et al. Kalirin-7 mediates cocaine-induced AMPA receptor and spine plasticity, enabling incentive sensitization. J Neurosci. 2013;33:11012-22 pubmed publisher
Pandey D, Goyal P, Dwivedi S, Siess W. Unraveling a novel Rac1-mediated signaling pathway that regulates cofilin dephosphorylation and secretion in thrombin-stimulated platelets. Blood. 2009;114:415-24 pubmed publisher
Harfouche R, Malak N, Brandes R, Karsan A, Irani K, Hussain S. Roles of reactive oxygen species in angiopoietin-1/tie-2 receptor signaling. FASEB J. 2005;19:1728-30 pubmed
Siu M, Wong E, Chan H, Kong D, Woo N, Tam K, et al. Differential expression and phosphorylation of Pak1 and Pak2 in ovarian cancer: effects on prognosis and cell invasion. Int J Cancer. 2010;127:21-31 pubmed publisher
product information
SKU :
2601S
Product-Name :
Phospho-PAK1 (Thr423)/PAK2 (Thr402) Antibody
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H, M, GP, (R)
Applications :
Western blot
Product-Category :
Cytoskeletal Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
61 to 67 (PAK2), 68 to 74 (PAK1/3)
Host :
Rabbit
Target :
PAK1 (Thr423) phosphate/PAK2 (Thr402) phosphate/PAK3 (Thr436) phosphate
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.