Acetyl-Histone H4 (Lys12) Antibody | Cell Signaling Technology 2591 product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

Acetyl-Histone H4 (Lys12) Antibody

catalog :

2591

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, rat

application :

western blot, immunocytochemistry

more info or order :

Cell Signaling Technology product webpage

citations: 10

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:1000	Kim T, Kim H, Kang Y, Yoon S, Lee J, Choi W, et al. Psammaplin A induces Sirtuin 1-dependent autophagic cell death in doxorubicin-resistant MCF-7/adr human breast cancer cells and xenografts. Biochim Biophys Acta. 2015;1850:401-10 pubmed publisher
western blot; human	Sanders Y, Hagood J, Liu H, Zhang W, Ambalavanan N, Thannickal V. Histone deacetylase inhibition promotes fibroblast apoptosis and ameliorates pulmonary fibrosis in mice. Eur Respir J. 2014;43:1448-58 pubmed publisher
western blot; human	Gray J, Haura E, Chiappori A, Tanvetyanon T, Williams C, Pinder Schenck M, et al. A phase I, pharmacokinetic, and pharmacodynamic study of panobinostat, an HDAC inhibitor, combined with erlotinib in patients with advanced aerodigestive tract tumors. Clin Cancer Res. 2014;20:1644-55 pubmed publisher
western blot; human	Zhang X, Liu H, Hock T, Thannickal V, Sanders Y. Histone deacetylase inhibition downregulates collagen 3A1 in fibrotic lung fibroblasts. Int J Mol Sci. 2013;14:19605-17 pubmed publisher
western blot; human; fig 6	Lauffer B, Mintzer R, Fong R, Mukund S, Tam C, Zilberleyb I, et al. Histone deacetylase (HDAC) inhibitor kinetic rate constants correlate with cellular histone acetylation but not transcription and cell viability. J Biol Chem. 2013;288:26926-43 pubmed publisher
	Wu Y, Ma S, Xia Y, Lu Y, Xiao S, Cao Y, et al. Loss of GCN5 leads to increased neuronal apoptosis by upregulating E2F1- and Egr-1-dependent BH3-only protein Bim. Cell Death Dis. 2017;8:e2570 pubmed publisher
	Thompson J, Nguyen Q, Singh M, Pavesic M, Nesterenko I, Nelson L, et al. Rho-associated kinase 1 inhibition is synthetically lethal with von Hippel-Lindau deficiency in clear cell renal cell carcinoma. Oncogene. 2017;36:1080-1089 pubmed publisher
	Zhang Z, Cai Y, Zou F, Bie B, Pan Z. Epigenetic suppression of GAD65 expression mediates persistent pain. Nat Med. 2011;17:1448-55 pubmed publisher
	Chung S, Sundar I, Hwang J, Yull F, Blackwell T, Kinnula V, et al. NF-?B inducing kinase, NIK mediates cigarette smoke/TNF?-induced histone acetylation and inflammation through differential activation of IKKs. PLoS ONE. 2011;6:e23488 pubmed publisher
	Rajendrasozhan S, Chung S, Sundar I, Yao H, Rahman I. Targeted disruption of NF-{kappa}B1 (p50) augments cigarette smoke-induced lung inflammation and emphysema in mice: a critical role of p50 in chromatin remodeling. Am J Physiol Lung Cell Mol Physiol. 2010;298:L197-209 pubmed publisher

product information

SKU :

2591S

Product-Name :

Acetyl-Histone H4 (Lys12) Antibody

Size :

100 ul

Price-(USD) :

274 USD

Species-x-Reactivity :

H, M, R, Mk

Applications :

Immunofluorescence (Immunocytochemistry)

Product-Category :

Chromatin Regulation / Nuclear Function

Shipping-Temp :

COLD

Storage-Temp :

-20°C

Product-Type :

Polyclonal Antibody

MW :

Host :

Rabbit

Target :

H4 (Lys13) acetylate

Primary-Protein :

Alt-Names :

H4,H4 histone family, member A,H4/A,H4/B,H4/C,H4/D,H4/E,H4/G,H4/H,H4/I,H4/J,H4/K,H4/M,H4/N,H4/O,H4F2,H4FA,H4FB,H4FC,H4FD,H4FE,H4FG,H4FH,H4FI,H4FJ,H4FK,H4FM,H4FN,H4FO,HIST1H4A,HIST1H4B,HIST1H4C,HIST1H4D,HIST1H4E,HIST1H4F,HIST1H4H,HIST1H4I,HIST1H4J,HIST1H4K,HIST1H4L,HIST2H4,HIST2H4A,HIST2H4B,HIST4H4,Histone H4,histone 1, H4a,histone cluster 1, H4a

more info or order :

Cell Signaling Technology product webpage