product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
PCNA (PC10) Mouse mAb
catalog :
2586
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
PC10
reactivity :
human, mouse, rat, chicken, bovine
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, other
citations: 122
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:1000; loading ...; fig 2c
Bahn M, Yu D, Lee M, Jo S, Lee J, Kim H, et al. Central role of Prominin-1 in lipid rafts during liver regeneration. Nat Commun. 2022;13:6219 pubmed publisher
  • immunohistochemistry; mouse; 1:4000; loading ...; fig 5c
Bashford A, Subramanian V. Hippocampals neurogenesis is impaired in mice with a deletion in the coiled coil domain of Talpid3-implications for Joubert syndrome. Hum Mol Genet. 2022;31:3245-3265 pubmed publisher
  • western blot; human; 1:500; loading ...; fig 5a
Su Y, Xu J, Gao R, Liu X, Liu T, Li C, et al. The Circ-CYP24A1-miR-224-PRLR Axis Impairs Cell Proliferation and Apoptosis in Recurrent Miscarriage. Front Physiol. 2022;13:778116 pubmed publisher
  • western blot; mouse; 1:2000; loading ...; fig 6b
Ha N, Sun J, Bian Q, Wu D, Wang X. Hdac4 Regulates the Proliferation of Neural Crest-Derived Osteoblasts During Murine Craniofacial Development. Front Physiol. 2022;13:819619 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:50; loading ...; fig 4d
Goto H, Inoue A, Piao L, Hu L, Huang Z, Meng X, et al. Proliferin-1 Ameliorates Cardiotoxin-Related Skeletal Muscle Repair in Mice. Stem Cells Int. 2021;2021:9202990 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 5b
Choe D, Lee E, Beeghly Fadiel A, Wilson A, Whalen M, Adunyah S, et al. High-Fat Diet-Induced Obese Effects of Adipocyte-Specific CXCR2 Conditional Knockout in the Peritoneal Tumor Microenvironment of Ovarian Cancer. Cancers (Basel). 2021;13: pubmed publisher
  • western blot; mouse; 1:500; loading ...; fig 5e
Tian X, Wang Y, Lu Y, Wang W, Du J, Chen S, et al. Conditional depletion of macrophages ameliorates cholestatic liver injury and fibrosis via lncRNA-H19. Cell Death Dis. 2021;12:646 pubmed publisher
  • immunohistochemistry - paraffin section; rat; 1:1000; loading ...; fig s2
Wang X, Li Z, Shao Q, Zhang C, Wang J, Han Z, et al. The intact parasympathetic nerve promotes submandibular gland regeneration through ductal cell proliferation. Cell Prolif. 2021;54:e13078 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:500; loading ...; fig 2b
Littlejohn E, DeSana A, Williams H, Chapman R, Joseph B, Juras J, et al. IGF1-Stimulated Posttraumatic Hippocampal Remodeling Is Not Dependent on mTOR. Front Cell Dev Biol. 2021;9:663456 pubmed publisher
  • immunohistochemistry; mouse; 1:200; loading ...; fig 1d
Mizukoshi M, Kaku M, Thant L, Kitami K, Arai M, Saito I, et al. In vivo cell proliferation analysis and cell-tracing reveal the global cellular dynamics of periodontal ligament cells under mechanical-loading. Sci Rep. 2021;11:9813 pubmed publisher
  • immunohistochemistry; mouse; 1:500; loading ...
Swahari V, Nakamura A, Hollville E, Stroud H, Simon J, Ptacek T, et al. MicroRNA-29 is an essential regulator of brain maturation through regulation of CH methylation. Cell Rep. 2021;35:108946 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 2b
Quintero M, Liu S, Xia Y, Huang Y, Zou Y, Li G, et al. Cdk5rap3 is essential for intestinal Paneth cell development and maintenance. Cell Death Dis. 2021;12:131 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:1000; loading ...; fig 2c
Dewhurst M, Ow J, Zafer G, Van Hul N, Wollmann H, Bisteau X, et al. Loss of hepatocyte cell division leads to liver inflammation and fibrosis. PLoS Genet. 2020;16:e1009084 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig s1b
Sepe L, Hartl K, Iftekhar A, Berger H, Kumar N, Goosmann C, et al. Genotoxic Effect of Salmonella Paratyphi A Infection on Human Primary Gallbladder Cells. MBio. 2020;11: pubmed publisher
  • immunohistochemistry; human; loading ...
Viloria K, Nasteska D, Briant L, Heising S, Larner D, Fine N, et al. Vitamin-D-Binding Protein Contributes to the Maintenance of α Cell Function and Glucagon Secretion. Cell Rep. 2020;31:107761 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 4c
Xing T, Benderman L, Sabu S, Parker J, Yang J, Lu Q, et al. Tight Junction Protein Claudin-7 Is Essential for Intestinal Epithelial Stem Cell Self-Renewal and Differentiation. Cell Mol Gastroenterol Hepatol. 2020;9:641-659 pubmed publisher
  • western blot; mouse; loading ...; fig 5a
Zhan Y, Li R, Feng C, Li X, Huang S, Wang L, et al. Chlorogenic acid inhibits esophageal squamous cell carcinoma growth in vitro and in vivo by downregulating the expression of BMI1 and SOX2. Biomed Pharmacother. 2020;121:109602 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 1d
  • immunocytochemistry; mouse; fig 5e
Wang D, Zheng X, Fu B, Nian Z, Qian Y, Sun R, et al. Hepatectomy promotes recurrence of liver cancer by enhancing IL-11-STAT3 signaling. EBioMedicine. 2019;46:119-132 pubmed publisher
  • immunohistochemistry; mouse; 1:600; loading ...; fig ex1c
Serra D, Mayr U, Boni A, Lukonin I, Rempfler M, Challet Meylan L, et al. Self-organization and symmetry breaking in intestinal organoid development. Nature. 2019;569:66-72 pubmed publisher
  • western blot; human; loading ...; fig 2b
Li Y, Li H, Duan Y, Cai X, You D, Zhou F, et al. Blockage of TGF-α Induced by Spherical Silica Nanoparticles Inhibits Epithelial-Mesenchymal Transition and Proliferation of Human Lung Epithelial Cells. Biomed Res Int. 2019;2019:8231267 pubmed publisher
  • western blot; mouse; 1:2000; loading ...; fig 3b
Jia Q, Yang F, Huang W, Zhang Y, Bao B, Li K, et al. Low Levels of Sox2 are required for Melanoma Tumor-Repopulating Cell Dormancy. Theranostics. 2019;9:424-435 pubmed publisher
  • immunocytochemistry; mouse; loading ...; fig 2e
Del Rosario B, Kriz A, Del Rosario A, Anselmo A, Fry C, White F, et al. Exploration of CTCF post-translation modifications uncovers Serine-224 phosphorylation by PLK1 at pericentric regions during the G2/M transition. elife. 2019;8: pubmed publisher
  • western blot; human; fig 7e
Xie H, Wang Y, Zhang H, Fan Q, Dai D, Zhuang L, et al. Tubular epithelial C1orf54 mediates protection and recovery from acute kidney injury. J Cell Mol Med. 2018;22:4985-4996 pubmed publisher
  • western blot; human; 1:1000; fig s4e
Chhipa R, Fan Q, Anderson J, Muraleedharan R, Huang Y, Ciraolo G, et al. AMP kinase promotes glioblastoma bioenergetics and tumour growth. Nat Cell Biol. 2018;20:823-835 pubmed publisher
  • western blot; mouse; fig 5b
Lee C, Hsieh T. Wuho/WDR4 deficiency inhibits cell proliferation and induces apoptosis via DNA damage in mouse embryonic fibroblasts. Cell Signal. 2018;47:16-26 pubmed publisher
  • western blot; human; 1:1000; fig 1c
Galanos P, Pappas G, Polyzos A, Kotsinas A, Svolaki I, Giakoumakis N, et al. Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability. Genome Biol. 2018;19:37 pubmed publisher
  • other; human; loading ...; fig 4c
Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 6c
Li F, Liu J, Bao R, Yan G, Feng X, Xu Y, et al. Acetylation accumulates PFKFB3 in cytoplasm to promote glycolysis and protects cells from cisplatin-induced apoptosis. Nat Commun. 2018;9:508 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 4d
Lu L, Finegold M, Johnson R. Hippo pathway coactivators Yap and Taz are required to coordinate mammalian liver regeneration. Exp Mol Med. 2018;50:e423 pubmed publisher
  • immunohistochemistry; mouse; 1:500; loading ...; fig 4a
Ngo H, Kim D, Cha Y, Na H, Surh Y. Nrf2 Mutagenic Activation Drives Hepatocarcinogenesis. Cancer Res. 2017;77:4797-4808 pubmed publisher
  • western blot; human; 1:2000; loading ...; fig 3b
  • immunohistochemistry; mouse; 1:4000; loading ...; fig 7b
Fu S, Xu H, Gu M, Liu C, Wang Q, Wan X, et al. Adiponectin deficiency contributes to the development and progression of benign prostatic hyperplasia in obesity. Sci Rep. 2017;7:43771 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:4000; loading ...; fig 3a
  • western blot; human; 1:1000; loading ...; fig 1d
Yang Y, Hu S, Liu J, Cui Y, Fan Y, Lv T, et al. CD8+ T cells promote proliferation of benign prostatic hyperplasia epithelial cells under low androgen level via modulation of CCL5/STAT5/CCND1 signaling pathway. Sci Rep. 2017;7:42893 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 3b
Jerić I, Maurer G, Cavallo A, Raguz J, Desideri E, Tarkowski B, et al. A cell-autonomous tumour suppressor role of RAF1 in hepatocarcinogenesis. Nat Commun. 2016;7:13781 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 3f
Dilley R, Verma P, Cho N, Winters H, Wondisford A, Greenberg R. Break-induced telomere synthesis underlies alternative telomere maintenance. Nature. 2016;539:54-58 pubmed publisher
  • western blot; human; fig 6
Nelson D, Jaber Hijazi F, Cole J, Robertson N, Pawlikowski J, Norris K, et al. Mapping H4K20me3 onto the chromatin landscape of senescent cells indicates a function in control of cell senescence and tumor suppression through preservation of genetic and epigenetic stability. Genome Biol. 2016;17:158 pubmed publisher
  • western blot; human; fig s1
Hrecka K, Hao C, Shun M, Kaur S, Swanson S, Florens L, et al. HIV-1 and HIV-2 exhibit divergent interactions with HLTF and UNG2 DNA repair proteins. Proc Natl Acad Sci U S A. 2016;113:E3921-30 pubmed publisher
  • western blot; mouse; fig 3
de Jong P, Taniguchi K, Harris A, Bertin S, Takahashi N, Duong J, et al. ERK5 signalling rescues intestinal epithelial turnover and tumour cell proliferation upon ERK1/2 abrogation. Nat Commun. 2016;7:11551 pubmed publisher
  • western blot; human
Xue H, Yuan G, Guo X, Liu Q, Zhang J, Gao X, et al. A novel tumor-promoting mechanism of IL6 and the therapeutic efficacy of tocilizumab: Hypoxia-induced IL6 is a potent autophagy initiator in glioblastoma via the p-STAT3-MIR155-3p-CREBRF pathway. Autophagy. 2016;12:1129-52 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 5a
Guo J, Wang X, Lu X, Jing R, Li J, Li C, et al. Unraveling molecular effects of ADAR1 overexpression in HEK293T cells by label-free quantitative proteomics. Cell Cycle. 2016;15:1591-601 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 5b
Muramatsu T, Kozaki K, Imoto S, Yamaguchi R, Tsuda H, Kawano T, et al. The hypusine cascade promotes cancer progression and metastasis through the regulation of RhoA in squamous cell carcinoma. Oncogene. 2016;35:5304-5316 pubmed publisher
  • western blot; mouse; fig 3
Zhao K, Zhang M, Zhang L, Wang P, Song G, Liu B, et al. Intracellular osteopontin stabilizes TRAF3 to positively regulate innate antiviral response. Sci Rep. 2016;6:23771 pubmed publisher
  • immunohistochemistry - paraffin section; human; fig 8
Huang J, Yao C, Chuang S, Yeh C, Lee L, Chen R, et al. Honokiol inhibits sphere formation and xenograft growth of oral cancer side population cells accompanied with JAK/STAT signaling pathway suppression and apoptosis induction. BMC Cancer. 2016;16:245 pubmed publisher
  • western blot; human; loading ...; fig 3a
Preet R, Siddharth S, Satapathy S, Das S, Nayak A, Das D, et al. Chk1 inhibitor synergizes quinacrine mediated apoptosis in breast cancer cells by compromising the base excision repair cascade. Biochem Pharmacol. 2016;105:23-33 pubmed publisher
  • western blot; mouse; 1:1000; tbl 1
Bertoldo M, Guibert E, Faure M, Guillou F, Ramé C, Nadal Desbarats L, et al. Specific deletion of AMP-activated protein kinase (α1AMPK) in mouse Sertoli cells modifies germ cell quality. Mol Cell Endocrinol. 2016;423:96-112 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:1000; fig 4
Aini H, Itaka K, Fujisawa A, Uchida H, Uchida S, Fukushima S, et al. Messenger RNA delivery of a cartilage-anabolic transcription factor as a disease-modifying strategy for osteoarthritis treatment. Sci Rep. 2016;6:18743 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 2e
Kanu N, Zhang T, Burrell R, Chakraborty A, Cronshaw J, DaCosta C, et al. RAD18, WRNIP1 and ATMIN promote ATM signalling in response to replication stress. Oncogene. 2016;35:4009-19 pubmed publisher
  • western blot; mouse; fig 2b
  • western blot; human; fig 6c
Yu D, Makkar G, Dong T, Strickland D, Sarkar R, Monahan T. MARCKS Signaling Differentially Regulates Vascular Smooth Muscle and Endothelial Cell Proliferation through a KIS-, p27kip1- Dependent Mechanism. PLoS ONE. 2015;10:e0141397 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100
Kaku M, Rosales Rocabado J, Kitami M, Ida T, Akiba Y, Yamauchi M, et al. Mechanical Loading Stimulates Expression of Collagen Cross-Linking Associated Enzymes in Periodontal Ligament. J Cell Physiol. 2016;231:926-33 pubmed publisher
  • western blot; human; loading ...; fig 6b
Reuther C, Heinzle V, Spampatti M, Vlotides G, de Toni E, Spöttl G, et al. Cabozantinib and Tivantinib, but Not INC280, Induce Antiproliferative and Antimigratory Effects in Human Neuroendocrine Tumor Cells in vitro: Evidence for 'Off-Target' Effects Not Mediated by c-Met Inhibition. Neuroendocrinology. 2016;103:383-401 pubmed publisher
  • western blot; mouse; 1:1000
Oláh G, Szczesny B, Brunyánszki A, López García I, Gerö D, Radák Z, et al. Differentiation-Associated Downregulation of Poly(ADP-Ribose) Polymerase-1 Expression in Myoblasts Serves to Increase Their Resistance to Oxidative Stress. PLoS ONE. 2015;10:e0134227 pubmed publisher
  • immunohistochemistry; rat
Chen W, Chen C, Chen N, Sung C, Wen Z. Neuroprotective Effects of Direct Intrathecal Administration of Granulocyte Colony-Stimulating Factor in Rats with Spinal Cord Injury. CNS Neurosci Ther. 2015;21:698-707 pubmed publisher
  • immunohistochemistry; chicken; 1:1000; fig 2a-d
Schock E, Chang C, Struve J, Chang Y, Chang J, Delany M, et al. Using the avian mutant talpid2 as a disease model for understanding the oral-facial phenotypes of oral-facial-digital syndrome. Dis Model Mech. 2015;8:855-66 pubmed publisher
  • immunohistochemistry; mouse; 1:300; fig 2, 4, 5
Trasino S, Benoit Y, Gudas L. Vitamin A deficiency causes hyperglycemia and loss of pancreatic β-cell mass. J Biol Chem. 2015;290:1456-73 pubmed publisher
  • western blot; mouse; fig 13
Edwards J, Bruno J, Key P, Cheng Y. Absence of chloride intracellular channel 4 (CLIC4) predisposes to acute kidney injury but has minimal impact on recovery. BMC Nephrol. 2014;15:54 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:3000
  • western blot; mouse; 1:3000
Xiao W, Feng Y, Holst J, Hartmann B, Yang H, Teitelbaum D. Glutamate prevents intestinal atrophy via luminal nutrient sensing in a mouse model of total parenteral nutrition. FASEB J. 2014;28:2073-87 pubmed publisher
  • immunohistochemistry; human
Knoblich K, Wang H, Sharma C, Fletcher A, Turley S, Hemler M. Tetraspanin TSPAN12 regulates tumor growth and metastasis and inhibits ?-catenin degradation. Cell Mol Life Sci. 2014;71:1305-14 pubmed publisher
Rodriguez Blanco J, Pednekar L, Penas C, Li B, Martin V, Long J, et al. Inhibition of WNT signaling attenuates self-renewal of SHH-subgroup medulloblastoma. Oncogene. 2017;36:6306-6314 pubmed publisher
Zheng X, Chen X, Xu L, Zhang M, Feng L, Yi P, et al. miR-203 inhibits augmented proliferation and metastasis of hepatocellular carcinoma residual in the promoted regenerating liver. Cancer Sci. 2017;108:338-346 pubmed publisher
Wen Q, Wang Y, Tang J, Cheng C, Liu Y. Sertoli Cell Wt1 Regulates Peritubular Myoid Cell and Fetal Leydig Cell Differentiation during Fetal Testis Development. PLoS ONE. 2016;11:e0167920 pubmed publisher
Collery R, Volberding P, Bostrom J, Link B, Besharse J. Loss of Zebrafish Mfrp Causes Nanophthalmia, Hyperopia, and Accumulation of Subretinal Macrophages. Invest Ophthalmol Vis Sci. 2016;57:6805-6814 pubmed publisher
Li S, Zhou Y, Zheng X, Wu X, Liang Y, Wang S, et al. Sphk1 promotes breast epithelial cell proliferation via NF-κB-p65-mediated cyclin D1 expression. Oncotarget. 2016;7:80579-80585 pubmed publisher
Zhao S, Tang H, Yan D, Fan J, Sun H, Wen Y, et al. DDA1 promotes stage IIB-IIC colon cancer progression by activating NFκB/CSN2/GSK-3β signaling. Oncotarget. 2016;7:19794-812 pubmed publisher
Cao J, Huang W. Compensatory Increase of Transglutaminase 2 Is Responsible for Resistance to mTOR Inhibitor Treatment. PLoS ONE. 2016;11:e0149388 pubmed publisher
Soares M, Cohen O, Low Y, Sartor R, Ellison T, Anil U, et al. Restoration of Nrf2 Signaling Normalizes the Regenerative Niche. Diabetes. 2016;65:633-46 pubmed publisher
Yan G, Wang Q, Hu S, Wang D, Qiao Y, Ma G, et al. Digoxin inhibits PDGF-BB-induced VSMC proliferation and migration through an increase in ILK signaling and attenuates neointima formation following carotid injury. Int J Mol Med. 2015;36:1001-11 pubmed publisher
Freeman J, Feng Y, Demehri F, Dempsey P, Teitelbaum D. TPN-associated intestinal epithelial cell atrophy is modulated by TLR4/EGF signaling pathways. FASEB J. 2015;29:2943-58 pubmed publisher
Li M, Wang Y, Song Y, Bu R, Yin B, Fei X, et al. MicroRNAs in renal cell carcinoma: a systematic review of clinical implications (Review). Oncol Rep. 2015;33:1571-8 pubmed publisher
Meier J, Haendler B, Seidel H, Groth P, Adams R, Ziegelbauer K, et al. Knockdown of platinum-induced growth differentiation factor 15 abrogates p27-mediated tumor growth delay in the chemoresistant ovarian cancer model A2780cis. Cancer Med. 2015;4:253-67 pubmed publisher
Boquoi A, Arora S, Chen T, Litwin S, Koh J, Enders G. Reversible cell cycle inhibition and premature aging features imposed by conditional expression of p16Ink4a. Aging Cell. 2015;14:139-47 pubmed publisher
Tam W, Ma C. Bipolar/rod-shaped microglia are proliferating microglia with distinct M1/M2 phenotypes. Sci Rep. 2014;4:7279 pubmed publisher
Das F, Bera A, Ghosh Choudhury N, Abboud H, Kasinath B, Choudhury G. TGFβ-induced deptor suppression recruits mTORC1 and not mTORC2 to enhance collagen I (α2) gene expression. PLoS ONE. 2014;9:e109608 pubmed publisher
Zhang X, Zhang R, Huang L, Wang P, Zhang Y, Jiang D, et al. TRAF1 is a key mediator for hepatic ischemia/reperfusion injury. Cell Death Dis. 2014;5:e1467 pubmed publisher
Zhang S, Zhu L, Chen H, Zhang R, Zhang P, Jiang D, et al. Interferon regulatory factor 9 is critical for neointima formation following vascular injury. Nat Commun. 2014;5:5160 pubmed publisher
Huang L, Zhang S, Zhang P, Zhang X, Zhu L, Chen K, et al. Interferon regulatory factor 7 protects against vascular smooth muscle cell proliferation and neointima formation. J Am Heart Assoc. 2014;3:e001309 pubmed publisher
Tsuneki M, Madri J. Adhesion molecule-mediated hippo pathway modulates hemangioendothelioma cell behavior. Mol Cell Biol. 2014;34:4485-99 pubmed publisher
Huang T, Tsai Y, Chiang S, Wang G, Kuo Y, Chang Y, et al. Anti-viral effect of a compound isolated from Liriope platyphylla against hepatitis B virus in vitro. Virus Res. 2014;192:16-24 pubmed publisher
Senger S, Kollmar O, Menger M, Schilling M, Rupertus K. Darbepoetin-? accelerates neovascularization and engraftment of extrahepatic colorectal metastases. Eur Surg Res. 2014;53:25-36 pubmed publisher
Kushwaha D, Ramakrishnan V, Ng K, Steed T, Nguyen T, Futalan D, et al. A genome-wide miRNA screen revealed miR-603 as a MGMT-regulating miRNA in glioblastomas. Oncotarget. 2014;5:4026-39 pubmed
Zhong B, Wang T, Lun X, Zhang J, Zheng S, Yang W, et al. Contribution of nestin positive esophageal squamous cancer cells on malignant proliferation, apoptosis, and poor prognosis. Cancer Cell Int. 2014;14:57 pubmed publisher
Cazzalini O, Sommatis S, Tillhon M, Dutto I, Bachi A, Rapp A, et al. CBP and p300 acetylate PCNA to link its degradation with nucleotide excision repair synthesis. Nucleic Acids Res. 2014;42:8433-48 pubmed publisher
Meeker S, Seamons A, Paik J, Treuting P, Brabb T, Grady W, et al. Increased dietary vitamin D suppresses MAPK signaling, colitis, and colon cancer. Cancer Res. 2014;74:4398-408 pubmed publisher
Chen J, Miller B, Furano A. Repair of naturally occurring mismatches can induce mutations in flanking DNA. elife. 2014;3:e02001 pubmed publisher
Lin X, Yi Z, Diao J, Shao M, Zhao L, Cai H, et al. ShaoYao decoction ameliorates colitis-associated colorectal cancer by downregulating proinflammatory cytokines and promoting epithelial-mesenchymal transition. J Transl Med. 2014;12:105 pubmed publisher
Forristal C, Henley S, MacDonald J, Bush J, Ort C, Passos D, et al. Loss of the mammalian DREAM complex deregulates chondrocyte proliferation. Mol Cell Biol. 2014;34:2221-34 pubmed publisher
Bonacci T, Audebert S, Camoin L, Baudelet E, Bidaut G, Garcia M, et al. Identification of new mechanisms of cellular response to chemotherapy by tracking changes in post-translational modifications by ubiquitin and ubiquitin-like proteins. J Proteome Res. 2014;13:2478-94 pubmed publisher
Farkas D, Kraskauskas D, Drake J, Alhussaini A, Kraskauskiene V, Bogaard H, et al. CXCR4 inhibition ameliorates severe obliterative pulmonary hypertension and accumulation of C-kit? cells in rats. PLoS ONE. 2014;9:e89810 pubmed publisher
Kitajima M, Dolmans M, Donnez O, Masuzaki H, Soares M, Donnez J. Enhanced follicular recruitment and atresia in cortex derived from ovaries with endometriomas. Fertil Steril. 2014;101:1031-7 pubmed publisher
Chen Z, Wang J, Cai L, Zhong B, Luo H, Hao Y, et al. Role of the stem cell-associated intermediate filament nestin in malignant proliferation of non-small cell lung cancer. PLoS ONE. 2014;9:e85584 pubmed publisher
Inoue A, Kikuchi S, Hishiki A, Shao Y, Heath R, Evison B, et al. A small molecule inhibitor of monoubiquitinated Proliferating Cell Nuclear Antigen (PCNA) inhibits repair of interstrand DNA cross-link, enhances DNA double strand break, and sensitizes cancer cells to cisplatin. J Biol Chem. 2014;289:7109-20 pubmed publisher
Yang Y, Hui C, Li J, Herrup K. The interaction of the atm genotype with inflammation and oxidative stress. PLoS ONE. 2014;9:e85863 pubmed publisher
Deghan Manshadi S, Ishiguro L, Sohn K, Medline A, Renlund R, Croxford R, et al. Folic acid supplementation promotes mammary tumor progression in a rat model. PLoS ONE. 2014;9:e84635 pubmed publisher
Tsuneki M, Madri J. CD44 regulation of endothelial cell proliferation and apoptosis via modulation of CD31 and VE-cadherin expression. J Biol Chem. 2014;289:5357-70 pubmed publisher
Yang M, Yu J, Chen N, Wang X, Liu X, Wang S, et al. Elevated microRNA-31 expression regulates colorectal cancer progression by repressing its target gene SATB2. PLoS ONE. 2013;8:e85353 pubmed publisher
Kato S, Hayakawa Y, Sakurai H, Saiki I, Yokoyama S. Mesenchymal-transitioned cancer cells instigate the invasion of epithelial cancer cells through secretion of WNT3 and WNT5B. Cancer Sci. 2014;105:281-9 pubmed publisher
Ng G, Yeh L, Zhang Y, Liu H, Feng G, Kao W, et al. Role of SH2-containing tyrosine phosphatase Shp2 in mouse corneal epithelial stratification. Invest Ophthalmol Vis Sci. 2013;54:7933-42 pubmed publisher
Akane H, Shiraki A, Imatanaka N, Akahori Y, Itahashi M, Abe H, et al. Glycidol induces axonopathy and aberrations of hippocampal neurogenesis affecting late-stage differentiation by exposure to rats in a framework of 28-day toxicity study. Toxicol Lett. 2014;224:424-32 pubmed publisher
Lv L, Wang F, Ma X, Yang Y, Wang Z, Liu H, et al. Mismatch repair protein MSH2 regulates translesion DNA synthesis following exposure of cells to UV radiation. Nucleic Acids Res. 2013;41:10312-22 pubmed publisher
Terai K, Shibata E, Abbas T, Dutta A. Degradation of p12 subunit by CRL4Cdt2 E3 ligase inhibits fork progression after DNA damage. J Biol Chem. 2013;288:30509-14 pubmed publisher
Dias M, Furtado K, Rodrigues M, Barbisan L. Effects of Ginkgo biloba on chemically-induced mammary tumors in rats receiving tamoxifen. BMC Complement Altern Med. 2013;13:93 pubmed publisher
Akane H, Shiraki A, Imatanaka N, Akahori Y, Itahashi M, Ohishi T, et al. Glycidol induces axonopathy by adult-stage exposure and aberration of hippocampal neurogenesis affecting late-stage differentiation by developmental exposure in rats. Toxicol Sci. 2013;134:140-54 pubmed publisher
Stiles J, Amaya C, Rains S, Diaz D, Pham R, Battiste J, et al. Targeting of beta adrenergic receptors results in therapeutic efficacy against models of hemangioendothelioma and angiosarcoma. PLoS ONE. 2013;8:e60021 pubmed publisher
Chen C, Sloane J, Li H, Aytan N, Giannaris E, Zeldich E, et al. The antiaging protein Klotho enhances oligodendrocyte maturation and myelination of the CNS. J Neurosci. 2013;33:1927-39 pubmed publisher
Ornelas I, Silva T, Fragel Madeira L, Ventura A. Inhibition of PI3K/Akt pathway impairs G2/M transition of cell cycle in late developing progenitors of the avian embryo retina. PLoS ONE. 2013;8:e53517 pubmed publisher
Yoshimi K, Hashimoto T, Niwa Y, Hata K, Serikawa T, Tanaka T, et al. Use of a chemically induced-colon carcinogenesis-prone Apc-mutant rat in a chemotherapeutic bioassay. BMC Cancer. 2012;12:448 pubmed publisher
Fujisawa H, Zhang Z, Sun W, Huang M, Kobayashi J, Yasuda H, et al. Histopathological changes in the pancreas from a spontaneous hyperglycemic cynomolgus monkey. J Toxicol Pathol. 2012;25:215-9 pubmed publisher
Yamada J, Jinno S. Novel objective classification of reactive microglia following hypoglossal axotomy using hierarchical cluster analysis. J Comp Neurol. 2013;521:1184-201 pubmed publisher
Syed F, Sherris D, Paus R, Varmeh S, Singh S, Pandolfi P, et al. Keloid disease can be inhibited by antagonizing excessive mTOR signaling with a novel dual TORC1/2 inhibitor. Am J Pathol. 2012;181:1642-58 pubmed publisher
Zhang X, Wang W, Mize G, Takayama T, True L, Vessella R. Protease-activated receptor 2 signaling upregulates angiogenic growth factors in renal cell carcinoma. Exp Mol Pathol. 2013;94:91-7 pubmed publisher
Garcia I, Crowther A, Gama V, Miller C, Miller C, Deshmukh M, et al. Bax deficiency prolongs cerebellar neurogenesis, accelerates medulloblastoma formation and paradoxically increases both malignancy and differentiation. Oncogene. 2013;32:2304-14 pubmed publisher
Niimi A, Chambers A, Downs J, Lehmann A. A role for chromatin remodellers in replication of damaged DNA. Nucleic Acids Res. 2012;40:7393-403 pubmed publisher
Kurose H, Shibata M, Iinuma M, Otsuki Y. Alterations in cell cycle and induction of apoptotic cell death in breast cancer cells treated with ?-mangostin extracted from mangosteen pericarp. J Biomed Biotechnol. 2012;2012:672428 pubmed publisher
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product information
SKU :
2586S
Product-Name :
PCNA (PC10) Mouse mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk, B, Pg
Applications :
Flow cytometry
Product-Category :
Cell Cycle / Checkpoint Control
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
36
Host :
Mouse
Target :
PCNA
Primary-Protein :
PCNA
Alt-Names :
Cyclin,DNA polymerase delta auxiliary protein,MGC8367,PCNA,Proliferating cell nuclear antigen
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.