| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; human; loading ...; fig 11
| Thangaraj K, Balasubramanian B, Park S, Natesan K, Liu W, Manju V. Orientin Induces G0/G1 Cell Cycle Arrest and Mitochondria Mediated Intrinsic Apoptosis in Human Colorectal Carcinoma HT29 Cells. Biomolecules. 2019;9: pubmed publisher |
- immunocytochemistry; human; 1:500; loading ...; fig 2s1a
- western blot; human; 1:1000; loading ...; fig 2s1b
| Elguindy M, Kopp F, Goodarzi M, Rehfeld F, Thomas A, Chang T, et al. PUMILIO, but not RBMX, binding is required for regulation of genomic stability by noncoding RNA NORAD. elife. 2019;8: pubmed publisher |
- immunocytochemistry; human; 1:800; loading ...
| Lieb S, Blaha Ostermann S, Kamper E, Rippka J, Schwarz C, Ehrenhöfer Wölfer K, et al. Werner syndrome helicase is a selective vulnerability of microsatellite instability-high tumor cells. elife. 2019;8: pubmed publisher |
- flow cytometry; human; loading ...; fig s7c
| Song K, Kim J, Lee Y, Bae H, Lee H, Woo S, et al. Mitochondrial reprogramming via ATP5H loss promotes multimodal cancer therapy resistance. J Clin Invest. 2018;128:4098-4114 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 7a
| Vera Ramirez L, Vodnala S, Nini R, Hunter K, Green J. Autophagy promotes the survival of dormant breast cancer cells and metastatic tumour recurrence. Nat Commun. 2018;9:1944 pubmed publisher |
- immunocytochemistry; human; loading ...; fig 2c
| Daddacha W, Koyen A, Bastien A, Head P, Dhere V, Nabeta G, et al. SAMHD1 Promotes DNA End Resection to Facilitate DNA Repair by Homologous Recombination. Cell Rep. 2017;20:1921-1935 pubmed publisher |
- immunocytochemistry; human; 1:100; fig 3h
| Skowron M, Niegisch G, Albrecht P, Van Koeveringe G, Romano A, Albers P, et al. Various Mechanisms Involve the Nuclear Factor (Erythroid-Derived 2)-Like (NRF2) to Achieve Cytoprotection in Long-Term Cisplatin-Treated Urothelial Carcinoma Cell Lines. Int J Mol Sci. 2017;18: pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 4a
| Patel N, Garikapati K, Pandita R, Singh D, Pandita T, Bhadra U, et al. miR-15a/miR-16 down-regulates BMI1, impacting Ub-H2A mediated DNA repair and breast cancer cell sensitivity to doxorubicin. Sci Rep. 2017;7:4263 pubmed publisher |
- western blot; human; loading ...; fig 2e
| Nayar U, Sadek J, Reichel J, Hernandez Hopkins D, Akar G, Barelli P, et al. Identification of a nucleoside analog active against adenosine kinase-expressing plasma cell malignancies. J Clin Invest. 2017;127:2066-2080 pubmed publisher |
- western blot; human; loading ...; fig 5g
| Mandl M, Zhang S, Ulrich M, Schmoeckel E, Mayr D, Vollmar A, et al. Inhibition of Cdk5 induces cell death of tumor-initiating cells. Br J Cancer. 2017;116:912-922 pubmed publisher |
- immunohistochemistry; mouse; 1:200; fig 4B;5C
| Houthuijzen J, Oosterom I, Hudson B, Hirasawa A, Daenen L, McLean C, et al. Fatty acid 16:4(n-3) stimulates a GPR120-induced signaling cascade in splenic macrophages to promote chemotherapy resistance. FASEB J. 2017;31:2195-2209 pubmed publisher |
- immunocytochemistry; human; loading ...; fig 7a
| Squillaro T, Antonucci I, Alessio N, Esposito A, Cipollaro M, Melone M, et al. Impact of lysosomal storage disorders on biology of mesenchymal stem cells: Evidences from in vitro silencing of glucocerebrosidase (GBA) and alpha-galactosidase A (GLA) enzymes. J Cell Physiol. 2017;232:3454-3467 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 7
| Aksoy P, Meneses P. The Role of DCT in HPV16 Infection of HaCaTs. PLoS ONE. 2017;12:e0170158 pubmed publisher |
- immunocytochemistry; human; fig 1c
| Santos J, Brianti M, Almeida V, Ortega M, Fischer W, Haas R, et al. Helicobacter pylori infection modulates the expression of miRNAs associated with DNA mismatch repair pathway. Mol Carcinog. 2017;56:1372-1379 pubmed publisher |
- western blot; human; loading ...; fig 3c
| Shibata E, Kiran M, Shibata Y, Singh S, Kiran S, Dutta A. Two subunits of human ORC are dispensable for DNA replication and proliferation. elife. 2016;5: pubmed publisher |
- western blot; human; loading ...; fig 3d
| Wu J, Sun Y, Zhang P, Qian M, Zhang H, Chen X, et al. The Fra-1-miR-134-SDS22 feedback loop amplifies ERK/JNK signaling and reduces chemosensitivity in ovarian cancer cells. Cell Death Dis. 2016;7:e2384 pubmed publisher |
- western blot; human; loading ...; fig s4a
| Wang D, Kon N, Lasso G, Jiang L, Leng W, Zhu W, et al. Acetylation-regulated interaction between p53 and SET reveals a widespread regulatory mode. Nature. 2016;538:118-122 pubmed publisher |
- immunocytochemistry; human; 1:500; fig 4
| Feringa F, Krenning L, Koch A, van den Berg J, van den Broek B, Jalink K, et al. Hypersensitivity to DNA damage in antephase as a safeguard for genome stability. Nat Commun. 2016;7:12618 pubmed publisher |
- immunocytochemistry; human; fig s4
| Moreno A, Carrington J, Albergante L, Al Mamun M, Haagensen E, Komseli E, et al. Unreplicated DNA remaining from unperturbed S phases passes through mitosis for resolution in daughter cells. Proc Natl Acad Sci U S A. 2016;113:E5757-64 pubmed publisher |
- immunocytochemistry; human; fig 2
| Ah Koon L, Lesage D, Lemadre E, Souissi I, Fagard R, Varin Blank N, et al. Cellular response to alkylating agent MNNG is impaired in STAT1-deficients cells. J Cell Mol Med. 2016;20:1956-65 pubmed publisher |
- immunohistochemistry; mouse; 1:1400; loading ...; fig 5a
| Adriaens C, Standaert L, Barra J, Latil M, Verfaillie A, Kalev P, et al. p53 induces formation of NEAT1 lncRNA-containing paraspeckles that modulate replication stress response and chemosensitivity. Nat Med. 2016;22:861-8 pubmed publisher |
- immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 5w
| Stock K, Estrada M, Vidic S, Gjerde K, Rudisch A, Santo V, et al. Capturing tumor complexity in vitro: Comparative analysis of 2D and 3D tumor models for drug discovery. Sci Rep. 2016;6:28951 pubmed publisher |
- immunocytochemistry; human; 1:400; fig 2
- western blot; human; 1:500; fig 2
| Ikeuchi M, Fukumoto Y, Honda T, Kuga T, Saito Y, Yamaguchi N, et al. v-Src Causes Chromosome Bridges in a Caffeine-Sensitive Manner by Generating DNA Damage. Int J Mol Sci. 2016;17: pubmed publisher |
- western blot; human; loading ...; fig 3b
| Zhao J, Niu X, Li X, Edwards H, Wang G, Wang Y, et al. Inhibition of CHK1 enhances cell death induced by the Bcl-2-selective inhibitor ABT-199 in acute myeloid leukemia cells. Oncotarget. 2016;7:34785-99 pubmed publisher |
- immunohistochemistry; human; 1:100; fig 4a
| Gruosso T, Mieulet V, Cardon M, Bourachot B, Kieffer Y, Devun F, et al. Chronic oxidative stress promotes H2AX protein degradation and enhances chemosensitivity in breast cancer patients. EMBO Mol Med. 2016;8:527-49 pubmed publisher |
- immunohistochemistry - paraffin section; human; 1:50; fig s1
| Koussounadis A, Langdon S, Um I, Kay C, Francis K, Harrison D, et al. Dynamic modulation of phosphoprotein expression in ovarian cancer xenograft models. BMC Cancer. 2016;16:205 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; loading ...; fig 2f
| Li T, Liu X, Jiang L, MANFREDI J, Zha S, Gu W. Loss of p53-mediated cell-cycle arrest, senescence and apoptosis promotes genomic instability and premature aging. Oncotarget. 2016;7:11838-49 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; fig 5j
| Ro S, Xue X, Ramakrishnan S, Cho C, Namkoong S, Jang I, et al. Tumor suppressive role of sestrin2 during colitis and colon carcinogenesis. elife. 2016;5:e12204 pubmed publisher |
- western blot; mouse; fig 1
- western blot; human; fig 1
| Thornton T, Delgado P, Chen L, Salas B, Krementsov D, Fernández M, et al. Inactivation of nuclear GSK3β by Ser(389) phosphorylation promotes lymphocyte fitness during DNA double-strand break response. Nat Commun. 2016;7:10553 pubmed publisher |
- western blot; mouse; fig 3
| GarcÃa Prat L, MartÃnez Vicente M, Perdiguero E, Ortet L, RodrÃguez Ubreva J, Rebollo E, et al. Autophagy maintains stemness by preventing senescence. Nature. 2016;529:37-42 pubmed publisher |
- immunocytochemistry; human; fig s1
- western blot; human; fig 1
| Hoffmann S, Smedegaard S, Nakamura K, Mortuza G, Räschle M, Ibañez de Opakua A, et al. TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress. J Cell Biol. 2016;212:63-75 pubmed publisher |
- western blot; human; 1:1000; fig 6a
| Huang R, Langdon S, Tse M, Mullen P, Um I, Faratian D, et al. The role of HDAC2 in chromatin remodelling and response to chemotherapy in ovarian cancer. Oncotarget. 2016;7:4695-711 pubmed publisher |
- western blot; human; fig s3e
| Petroni M, Sardina F, Heil C, Sahún Roncero M, Colicchia V, Veschi V, et al. The MRN complex is transcriptionally regulated by MYCN during neural cell proliferation to control replication stress. Cell Death Differ. 2016;23:197-206 pubmed publisher |
| Alessio N, Squillaro T, Ozcan S, Di Bernardo G, Venditti M, Melone M, et al. Stress and stem cells: adult Muse cells tolerate extensive genotoxic stimuli better than mesenchymal stromal cells. Oncotarget. 2018;9:19328-19341 pubmed publisher |
| Ding S, Diep J, Feng N, Ren L, Li B, Ooi Y, et al. STAG2 deficiency induces interferon responses via cGAS-STING pathway and restricts virus infection. Nat Commun. 2018;9:1485 pubmed publisher |
| Kedves A, Gleim S, Liang X, Bonal D, Sigoillot F, Harbinski F, et al. Recurrent ubiquitin B silencing in gynecological cancers establishes dependence on ubiquitin C. J Clin Invest. 2017;127:4554-4568 pubmed publisher |
| Xue X, Bredell B, Anderson E, Martin A, Mays C, Nagao Kitamoto H, et al. Quantitative proteomics identifies STEAP4 as a critical regulator of mitochondrial dysfunction linking inflammation and colon cancer. Proc Natl Acad Sci U S A. 2017;114:E9608-E9617 pubmed publisher |
| Kojima K, Maeda A, Yoshimura M, Nishida Y, Kimura S. The pathophysiological significance of PPM1D and therapeutic targeting of PPM1D-mediated signaling by GSK2830371 in mantle cell lymphoma. Oncotarget. 2016;7:69625-69637 pubmed publisher |
| Amani V, Prince E, Alimova I, Balakrishnan I, Birks D, Donson A, et al. Polo-like Kinase 1 as a potential therapeutic target in Diffuse Intrinsic Pontine Glioma. BMC Cancer. 2016;16:647 pubmed publisher |
| Pederiva C, Böhm S, Julner A, Farnebo M. Splicing controls the ubiquitin response during DNA double-strand break repair. Cell Death Differ. 2016;23:1648-57 pubmed publisher |
| Bullova P, Cougnoux A, Abunimer L, Kopacek J, Pastorekova S, Pacak K. Hypoxia potentiates the cytotoxic effect of piperlongumine in pheochromocytoma models. Oncotarget. 2016;7:40531-40545 pubmed publisher |
| Suzuki A, Hirasaki M, Hishida T, Wu J, Okamura D, Ueda A, et al. Loss of MAX results in meiotic entry in mouse embryonic and germline stem cells. Nat Commun. 2016;7:11056 pubmed publisher |
