product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Acetyl-p53 (Lys379) Antibody
catalog :
2570
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot
citations: 19
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:2000; loading ...; fig 1a
Nakazawa H, Chang K, Shinozaki S, Yasukawa T, Ishimaru K, Yasuhara S, et al. iNOS as a Driver of Inflammation and Apoptosis in Mouse Skeletal Muscle after Burn Injury: Possible Involvement of Sirt1 S-Nitrosylation-Mediated Acetylation of p65 NF-κB and p53. PLoS ONE. 2017;12:e0170391 pubmed publisher
  • western blot; human; fig 8a
Kumar P, Sharad S, Petrovics G, Mohamed A, Dobi A, Sreenath T, et al. Loss of miR-449a in ERG-associated prostate cancer promotes the invasive phenotype by inducing SIRT1. Oncotarget. 2016;7:22791-806 pubmed publisher
  • western blot; mouse; fig s1
Barroso González J, Auclair S, Luan S, Thomas L, Atkins K, Aslan J, et al. PACS-2 mediates the ATM and NF-κB-dependent induction of anti-apoptotic Bcl-xL in response to DNA damage. Cell Death Differ. 2016;23:1448-57 pubmed publisher
  • western blot; mouse; 1:500; fig 5
Heyward F, Gilliam D, Coleman M, Gavin C, Wang J, Kaas G, et al. Obesity Weighs down Memory through a Mechanism Involving the Neuroepigenetic Dysregulation of Sirt1. J Neurosci. 2016;36:1324-35 pubmed publisher
  • western blot; mouse; 1:1000; fig 2d
Kondo H, Kim H, Wang L, Okada M, Paul C, Millard R, et al. Blockade of senescence-associated microRNA-195 in aged skeletal muscle cells facilitates reprogramming to produce induced pluripotent stem cells. Aging Cell. 2016;15:56-66 pubmed publisher
  • western blot; mouse; loading ...; fig 4b
Singh S, Chand H, Gundavarapu S, Saeed A, Langley R, Tesfaigzi Y, et al. HIF-1α Plays a Critical Role in the Gestational Sidestream Smoke-Induced Bronchopulmonary Dysplasia in Mice. PLoS ONE. 2015;10:e0137757 pubmed publisher
  • western blot; mouse; fig 6a
Lebrun Julien F, Suter U. Combined HDAC1 and HDAC2 Depletion Promotes Retinal Ganglion Cell Survival After Injury Through Reduction of p53 Target Gene Expression. ASN Neuro. 2015;7: pubmed publisher
  • western blot; mouse; fig 2
Sykora P, Misiak M, Wang Y, Ghosh S, Leandro G, Liu D, et al. DNA polymerase β deficiency leads to neurodegeneration and exacerbates Alzheimer disease phenotypes. Nucleic Acids Res. 2015;43:943-59 pubmed publisher
  • western blot; mouse; loading ...; fig s6a
Healy M, Chow J, Byrne F, Breen D, Leitinger N, Li C, et al. Dietary effects on liver tumor burden in mice treated with the hepatocellular carcinogen diethylnitrosamine. J Hepatol. 2015;62:599-606 pubmed publisher
  • western blot; human; 1:1000; tbl 1
Vega Naredo I, Cunha Oliveira T, Serafim T, Sardao V, Oliveira P. Analysis of pro-apoptotic protein trafficking to and from mitochondria. Methods Mol Biol. 2015;1241:163-80 pubmed publisher
  • western blot; mouse
Meijer D, Sun Y, Liu T, Kane M, Alberta J, Adelmant G, et al. An amino terminal phosphorylation motif regulates intranuclear compartmentalization of Olig2 in neural progenitor cells. J Neurosci. 2014;34:8507-18 pubmed publisher
  • western blot; mouse
Brochier C, Dennis G, Rivieccio M, McLaughlin K, Coppola G, Ratan R, et al. Specific acetylation of p53 by HDAC inhibition prevents DNA damage-induced apoptosis in neurons. J Neurosci. 2013;33:8621-32 pubmed publisher
  • western blot; mouse
Wang Y, Zhao X, Shi D, Chen P, Yu Y, Yang L, et al. Overexpression of SIRT1 promotes high glucose-attenuated corneal epithelial wound healing via p53 regulation of the IGFBP3/IGF-1R/AKT pathway. Invest Ophthalmol Vis Sci. 2013;54:3806-14 pubmed publisher
  • western blot; mouse; fig 5
Contreras A, Mebratu Y, Delgado M, Montaño G, Hu C, Ryter S, et al. Deacetylation of p53 induces autophagy by suppressing Bmf expression. J Cell Biol. 2013;201:427-37 pubmed publisher
Cereijo R, Gallego Escuredo J, Moure R, Villarroya J, Domingo J, Fontdevila J, et al. The Molecular Signature of HIV-1-Associated Lipomatosis Reveals Differential Involvement of Brown and Beige/Brite Adipocyte Cell Lineages. PLoS ONE. 2015;10:e0136571 pubmed publisher
Choi H, Choi Y, Kang H, Lim E, Park S, Lee H, et al. PINK1 positively regulates HDAC3 to suppress dopaminergic neuronal cell death. Hum Mol Genet. 2015;24:1127-41 pubmed publisher
Li X, Fang E, Scheibye Knudsen M, Cui H, Qiu L, Li J, et al. Di-(2-ethylhexyl) phthalate inhibits DNA replication leading to hyperPARylation, SIRT1 attenuation, and mitochondrial dysfunction in the testis. Sci Rep. 2014;4:6434 pubmed publisher
Dayan C, Hales B. Effects of ethylene glycol monomethyl ether and its metabolite, 2-methoxyacetic acid, on organogenesis stage mouse limbs in vitro. Birth Defects Res B Dev Reprod Toxicol. 2014;101:254-61 pubmed publisher
Aranha M, Santos D, Sola S, Steer C, Rodrigues C. miR-34a regulates mouse neural stem cell differentiation. PLoS ONE. 2011;6:e21396 pubmed publisher
product information
SKU :
2570S
Product-Name :
Acetyl-p53 (Lys379) Antibody
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H, M
Applications :
Western blot
Product-Category :
Cell Cycle / Checkpoint Control
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
53
Host :
Rabbit
Target :
p53 (Lys382) acetylate
Primary-Protein :
p53
Alt-Names :
Antigen NY-CO-13,Cellular tumor antigen p53,FLJ92943,LFS1,P53,Phosphoprotein p53,TP53,TRP53,Tumor suppressor p53,p53 antigen,p53 transformation suppressor,p53 tumor suppressor,transformation-related protein 53,tumor protein p53
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.