product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
GLI1 (V812) Antibody
catalog :
2534
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunoprecipitation, western blot knockout validation
citations: 10
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; human; loading ...; fig 4a
Adams C, Htwe H, Marsh T, Wang A, Montoya M, Subbaraj L, et al. Transcriptional control of subtype switching ensures adaptation and growth of pancreatic cancer. elife. 2019;8: pubmed publisher
  • western blot; human; 1:1000; loading ...; fig s3a
Han B, Sun Z, Yu T, Wang Y, Kuang L, Li T, et al. SPOP-PTEN-SUFU axis promotes progression of clear cell renal cell carcinoma via activating SHH and WNT pathway. Cell Death Discov. 2021;7:120 pubmed publisher
  • western blot; human; loading ...; fig 3a
Koeniger A, Brichkina A, Nee I, Dempwolff L, Hupfer A, Galperin I, et al. Activation of Cilia-Independent Hedgehog/GLI1 Signaling as a Novel Concept for Neuroblastoma Therapy. Cancers (Basel). 2021;13: pubmed publisher
  • western blot; mouse; loading ...; fig s3e
Yao C, Haensel D, Gaddam S, Patel T, Atwood S, Sarin K, et al. AP-1 and TGFß cooperativity drives non-canonical Hedgehog signaling in resistant basal cell carcinoma. Nat Commun. 2020;11:5079 pubmed publisher
  • immunohistochemistry; human; loading ...; fig 1b
  • western blot; human; loading ...; fig 1b
Mirza A, McKellar S, Urman N, Brown A, Hollmig T, Aasi S, et al. LAP2 Proteins Chaperone GLI1 Movement between the Lamina and Chromatin to Regulate Transcription. Cell. 2019;176:198-212.e15 pubmed publisher
  • immunohistochemistry; human; loading ...; fig 3a
Jia Y, Gu D, Wan J, Yu B, Zhang X, Chiorean E, et al. The role of GLI-SOX2 signaling axis for gemcitabine resistance in pancreatic cancer. Oncogene. 2019;38:1764-1777 pubmed publisher
  • western blot; mouse; 1:500; loading ...; fig 4p
Nakagawa N, Li J, Yabuno Nakagawa K, Eom T, Cowles M, Mapp T, et al. APC sets the Wnt tone necessary for cerebral cortical progenitor development. Genes Dev. 2017;31:1679-1692 pubmed publisher
  • western blot; rat; 1:1000; loading ...; fig 1a
Yao P, Manor U, Petralia R, Brose R, Wu R, Ott C, et al. Sonic hedgehog pathway activation increases mitochondrial abundance and activity in hippocampal neurons. Mol Biol Cell. 2017;28:387-395 pubmed publisher
Gonnissen A, Isebaert S, McKee C, Muschel R, Haustermans K. The Effect of Metformin and GANT61 Combinations on the Radiosensitivity of Prostate Cancer Cells. Int J Mol Sci. 2017;18: pubmed publisher
Xu T, Zhang H, Park S, Venneti S, Kuick R, Ha K, et al. Loss of Pin1 Suppresses Hedgehog-Driven Medulloblastoma Tumorigenesis. Neoplasia. 2017;19:216-225 pubmed publisher
product information
SKU :
2534S
Product-Name :
GLI1 (V812) Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, (M, R)
Applications :
Immunoprecipitation
Product-Category :
Developmental Biology
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
160
Host :
Rabbit
Target :
GLI1
Primary-Protein :
GLI1
Alt-Names :
GLI,GLI family zinc finger 1,GLI1,Glioma-associated oncogene,Oncogene GLI,Zinc finger protein GLI1,glioma-associated oncogene family zinc finger 1,glioma-associated oncogene homolog 1 (zinc finger protein)
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.