product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
p53 (7F5) Rabbit mAb
catalog :
2527S
quantity :
100 ul
price :
235 USD
clonality :
monoclonal
host :
rabbit
clone name :
7F5
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, chromatin immunoprecipitation
more info or order :
Cell Signaling Technology product webpage
citations: 6
Published Application/Species/DilutionReference
  • western blot (knockdown validation); human; fig 6
Ma T, Fan B, Zhang C, Zhao H, Han C, Gao C, et al. Metabonomics applied in exploring the antitumour mechanism of physapubenolide on hepatocellular carcinoma cells by targeting glycolysis through the Akt-p53 pathway. Sci Rep. 2016;6:29926 pubmed publisher
  • western blot; human; fig 2
Chernova T, Sun X, Powley I, Galavotti S, Grosso S, Murphy F, et al. Molecular profiling reveals primary mesothelioma cell lines recapitulate human disease. Cell Death Differ. 2016;23:1152-64 pubmed publisher
  • immunohistochemistry; human; 1:200; fig 1
  • western blot; human; 1:1000; fig 2
Wang H, Bao W, Jiang F, Che Q, Chen Z, Wang F, et al. Mutant p53 (p53-R248Q) functions as an oncogene in promoting endometrial cancer by up-regulating REGγ. Cancer Lett. 2015;360:269-79 pubmed publisher
  • western blot; human; fig 5
Brohl A, Solomon D, Chang W, Wang J, Song Y, Sindiri S, et al. The genomic landscape of the Ewing Sarcoma family of tumors reveals recurrent STAG2 mutation. PLoS Genet. 2014;10:e1004475 pubmed publisher
  • immunocytochemistry; human
Peltonen K, Colis L, Liu H, Jäämaa S, Zhang Z, af Hällström T, et al. Small molecule BMH-compounds that inhibit RNA polymerase I and cause nucleolar stress. Mol Cancer Ther. 2014;13:2537-46 pubmed publisher
Ho D, Kim H, Kim J, Sim H, Ahn H, Kim J, et al. Leucine-Rich Repeat Kinase 2 (LRRK2) phosphorylates p53 and induces p21(WAF1/CIP1) expression. Mol Brain. 2015;8:54 pubmed publisher
product information
SKU :
2527S
Product-Name :
p53 (7F5) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, Mk
Applications :
Chromatin Immunoprecipitation
Product-Category :
Cell Cycle / Checkpoint Control
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
53
Host :
Rabbit
Target :
p53
Primary-Protein :
p53
Alt-Names :
Antigen NY-CO-13,Cellular tumor antigen p53,FLJ92943,LFS1,P53,Phosphoprotein p53,TP53,TRP53,Tumor suppressor p53,p53 antigen,p53 transformation suppressor,p53 tumor suppressor,transformation-related protein 53,tumor protein p53
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.