product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Acetyl-p53 (Lys382) Antibody
catalog :
2525S
quantity :
100 ul
price :
274 USD
clonality :
polyclonal
host :
rabbit
reactivity :
human, mouse
application :
western blot, immunocytochemistry, immunoprecipitation
citations: 14
Published Application/Species/DilutionReference
  • western blot; human; fig 3
Beard J, Tenga A, Hills J, Hoyer J, Cherian M, Wang Y, et al. The orphan nuclear receptor NR4A2 is part of a p53-microRNA-34 network. Sci Rep. 2016;6:25108 pubmed publisher
  • immunoprecipitation; human; fig 5
Liu X, Ehmed E, Li B, Dou J, Qiao X, Jiang W, et al. Breast cancer metastasis suppressor 1 modulates SIRT1-dependent p53 deacetylation through interacting with DBC1. Am J Cancer Res. 2016;6:1441-9 pubmed
  • western blot; human; fig 2
Ivanschitz L, Takahashi Y, Jollivet F, Ayrault O, Le Bras M, De The H. PML IV/ARF interaction enhances p53 SUMO-1 conjugation, activation, and senescence. Proc Natl Acad Sci U S A. 2015;112:14278-83 pubmed publisher
  • western blot; human
Wong P, Yeoh C, Ahmad A, Chelala C, Gillett C, Speirs V, et al. Identification of MAGEA antigens as causal players in the development of tamoxifen-resistant breast cancer. Oncogene. 2014;33:4579-88 pubmed publisher
  • western blot; human
Ji X, Lu H, Zhou Q, Luo K. LARP7 suppresses P-TEFb activity to inhibit breast cancer progression and metastasis. elife. 2014;3:e02907 pubmed publisher
  • western blot; human; fig 1a
  • western blot; mouse; fig 1b
Lau A, Liu P, Inuzuka H, Gao D. SIRT1 phosphorylation by AMP-activated protein kinase regulates p53 acetylation. Am J Cancer Res. 2014;4:245-55 pubmed
  • western blot; human
Du Y, Teng X, Wang N, Zhang X, Chen J, Ding P, et al. NF-κB and enhancer-binding CREB protein scaffolded by CREB-binding protein (CBP)/p300 proteins regulate CD59 protein expression to protect cells from complement attack. J Biol Chem. 2014;289:2711-24 pubmed publisher
  • immunocytochemistry; human; fig 5
Contreras A, Mebratu Y, Delgado M, Montaño G, Hu C, Ryter S, et al. Deacetylation of p53 induces autophagy by suppressing Bmf expression. J Cell Biol. 2013;201:427-37 pubmed publisher
  • western blot; human; 1:1000
Yuan Y, Tang A, Castoreno A, Kuo S, Wang Q, Kuballa P, et al. Gossypol and an HMT G9a inhibitor act in synergy to induce cell death in pancreatic cancer cells. Cell Death Dis. 2013;4:e690 pubmed publisher
  • western blot; human
Armour S, Bennett E, Braun C, Zhang X, McMahon S, Gygi S, et al. A high-confidence interaction map identifies SIRT1 as a mediator of acetylation of USP22 and the SAGA coactivator complex. Mol Cell Biol. 2013;33:1487-502 pubmed publisher
  • western blot; human
Wang Y, Zhao X, Shi D, Chen P, Yu Y, Yang L, et al. Overexpression of SIRT1 promotes high glucose-attenuated corneal epithelial wound healing via p53 regulation of the IGFBP3/IGF-1R/AKT pathway. Invest Ophthalmol Vis Sci. 2013;54:3806-14 pubmed publisher
Li Y, Xu S, Jiang B, Cohen R, Zang M. Activation of sterol regulatory element binding protein and NLRP3 inflammasome in atherosclerotic lesion development in diabetic pigs. PLoS ONE. 2013;8:e67532 pubmed publisher
Zhang Z, Kakutani K, Maeno K, Takada T, Yurube T, Doita M, et al. Expression of silent mating type information regulator 2 homolog 1 and its role in human intervertebral disc cell homeostasis. Arthritis Res Ther. 2011;13:R200 pubmed publisher
Kumazawa T, Nishimura K, Kuroda T, Ono W, Yamaguchi C, Katagiri N, et al. Novel nucleolar pathway connecting intracellular energy status with p53 activation. J Biol Chem. 2011;286:20861-9 pubmed publisher
product information
SKU :
2525S
Product-Name :
Acetyl-p53 (Lys382) Antibody
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H
Applications :
Western blot
Product-Category :
Cell Cycle / Checkpoint Control
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
53
Host :
Rabbit
Target :
p53 (Lys382) acetylate
Primary-Protein :
p53
Alt-Names :
Antigen NY-CO-13,Cellular tumor antigen p53,FLJ92943,LFS1,P53,Phosphoprotein p53,TP53,TRP53,Tumor suppressor p53,p53 antigen,p53 transformation suppressor,p53 tumor suppressor,transformation-related protein 53,tumor protein p53
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.