product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
SUFU (C81H7) Rabbit mAb
catalog :
2522
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
C81H7
reactivity :
human, mouse
application :
western blot, immunoprecipitation
citations: 10
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 4b
Lu J, Liu L, Zheng M, Li X, Wu A, Wu Q, et al. MEKK2 and MEKK3 suppress Hedgehog pathway-dependent medulloblastoma by inhibiting GLI1 function. Oncogene. 2018;37:3864-3878 pubmed publisher
  • western blot; human; fig 1
Raducu M, Fung E, Serres S, Infante P, Barberis A, Fischer R, et al. SCF (Fbxl17) ubiquitylation of Sufu regulates Hedgehog signaling and medulloblastoma development. EMBO J. 2016;35:1400-16 pubmed publisher
  • immunoprecipitation; mouse; fig 8f
  • western blot; mouse; fig 4j
Emechebe U, Kumar P P, Rozenberg J, Moore B, Firment A, Mirshahi T, et al. T-box3 is a ciliary protein and regulates stability of the Gli3 transcription factor to control digit number. elife. 2016;5: pubmed publisher
  • immunoprecipitation; mouse; fig 8
  • western blot; mouse; 1:1000; fig 8
Yan B, Zhang Z, Jin D, Cai C, Jia C, Liu W, et al. mTORC1 regulates PTHrP to coordinate chondrocyte growth, proliferation and differentiation. Nat Commun. 2016;7:11151 pubmed publisher
  • western blot; human; 1:1000; fig s1
Di Magno L, Basile A, Coni S, Manni S, Sdruscia G, D Amico D, et al. The energy sensor AMPK regulates Hedgehog signaling in human cells through a unique Gli1 metabolic checkpoint. Oncotarget. 2016;7:9538-49 pubmed publisher
  • western blot; human; fig 3
Xing Z, Lin A, Li C, Liang K, Wang S, Liu Y, et al. lncRNA directs cooperative epigenetic regulation downstream of chemokine signals. Cell. 2014;159:1110-1125 pubmed publisher
  • western blot; human; loading ...; fig 1f
Zahreddine H, Culjkovic Kraljacic B, Assouline S, Gendron P, Romeo A, Morris S, et al. The sonic hedgehog factor GLI1 imparts drug resistance through inducible glucuronidation. Nature. 2014;511:90-3 pubmed publisher
Eguether T, Cordelières F, Pazour G. Intraflagellar transport is deeply integrated in hedgehog signaling. Mol Biol Cell. 2018;29:1178-1189 pubmed publisher
Hoelzl M, Heby Henricson K, Gerling M, Dias J, Kuiper R, Trünkle C, et al. Differential requirement of SUFU in tissue development discovered in a hypomorphic mouse model. Dev Biol. 2017;429:132-146 pubmed publisher
Shimada Y, Katsube K, Kabasawa Y, Morita K, Omura K, Yamaguchi A, et al. Integrated genotypic analysis of hedgehog-related genes identifies subgroups of keratocystic odontogenic tumor with distinct clinicopathological features. PLoS ONE. 2013;8:e70995 pubmed publisher
product information
SKU :
2522S
Product-Name :
SUFU (C81H7) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, Mk
Applications :
Immunoprecipitation
Product-Category :
Developmental Biology
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
54
Host :
Rabbit
Target :
SUFU
Primary-Protein :
SUFU
Alt-Names :
PRO1280,SUFU,SUFUH,SUFUXL,Suppressor of fused homolog,suppressor of fused homolog (Drosophila)
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.