product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
PSD95 Antibody
catalog :
2507
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - frozen section, western blot knockout validation
citations: 14
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; mouse; loading ...; fig 6a
  • western blot; rat; loading ...; fig s4a
Won S, Incontro S, Nicoll R, Roche K. PSD-95 stabilizes NMDA receptors by inducing the degradation of STEP61. Proc Natl Acad Sci U S A. 2016;113:E4736-44 pubmed publisher
  • western blot; mouse; loading ...; fig 4p
Zhou Q, Li S, Li M, Ke D, Wang Q, Yang Y, et al. Human tau accumulation promotes glycogen synthase kinase-3β acetylation and thus upregulates the kinase: A vicious cycle in Alzheimer neurodegeneration. EBioMedicine. 2022;78:103970 pubmed publisher
  • western blot; mouse; 1:5000; fig s2d
Hu D, Sun X, Magpusao A, Fedorov Y, Thompson M, Wang B, et al. Small-molecule suppression of calpastatin degradation reduces neuropathology in models of Huntington's disease. Nat Commun. 2021;12:5305 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 6e
Stojakovic A, Trushin S, Sheu A, Khalili L, Chang S, Li X, et al. Partial inhibition of mitochondrial complex I ameliorates Alzheimer's disease pathology and cognition in APP/PS1 female mice. Commun Biol. 2021;4:61 pubmed publisher
  • western blot; human; loading ...; fig 2a
Yao W, Tambini M, Liu X, D ADAMIO L. Tuning of glutamate, but not GABA, release by an intra-synaptic vesicles APP domain whose function can be modulated by β- or α-secretase cleavage. J Neurosci. 2019;: pubmed publisher
  • western blot; mouse; 1:1000; fig 3b
Zhao Y, Sun X, Qi X. Inhibition of Drp1 hyperactivation reduces neuropathology and behavioral deficits in zQ175 knock-in mouse model of Huntington's disease. Biochem Biophys Res Commun. 2018;507:319-323 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 4
Lu F, Shao G, Wang Y, Guan S, Burlingame A, Liu X, et al. Hypoxia-ischemia modifies postsynaptic GluN2B-containing NMDA receptor complexes in the neonatal mouse brain. Exp Neurol. 2018;299:65-74 pubmed publisher
  • western blot; rat; 1:1000; loading ...; fig 3a
Arcego D, Toniazzo A, Krolow R, Lampert C, Berlitz C, Dos Santos Garcia E, et al. Impact of High-Fat Diet and Early Stress on Depressive-Like Behavior and Hippocampal Plasticity in Adult Male Rats. Mol Neurobiol. 2018;55:2740-2753 pubmed publisher
  • western blot; mouse; loading ...; fig 3a
Croft C, Wade M, Kurbatskaya K, Mastrandreas P, Hughes M, Phillips E, et al. Membrane association and release of wild-type and pathological tau from organotypic brain slice cultures. Cell Death Dis. 2017;8:e2671 pubmed publisher
  • immunocytochemistry; mouse; loading ...; fig 1g
  • western blot; mouse; loading ...; fig 1h
Bodrikov V, Pauschert A, Kochlamazashvili G, Stuermer C. Reggie-1 and reggie-2 (flotillins) participate in Rab11a-dependent cargo trafficking, spine synapse formation and LTP-related AMPA receptor (GluA1) surface exposure in mouse hippocampal neurons. Exp Neurol. 2017;289:31-45 pubmed publisher
  • western blot; human; fig 5
Kurbatskaya K, Phillips E, Croft C, Dentoni G, Hughes M, Wade M, et al. Upregulation of calpain activity precedes tau phosphorylation and loss of synaptic proteins in Alzheimer's disease brain. Acta Neuropathol Commun. 2016;4:34 pubmed publisher
  • immunohistochemistry; mouse; 1:500; fig 7
Buniello A, Ingham N, Lewis M, Huma A, Martinez Vega R, Varela Nieto I, et al. Wbp2 is required for normal glutamatergic synapses in the cochlea and is crucial for hearing. EMBO Mol Med. 2016;8:191-207 pubmed publisher
Duan Z, Zhang F, Li F, Luan Y, Guo P, Li Y, et al. Protease activated receptor 1 (PAR1) enhances Src-mediated tyrosine phosphorylation of NMDA receptor in intracerebral hemorrhage (ICH). Sci Rep. 2016;6:29246 pubmed publisher
Shen M, Shi H. Estradiol and Estrogen Receptor Agonists Oppose Oncogenic Actions of Leptin in HepG2 Cells. PLoS ONE. 2016;11:e0151455 pubmed publisher
product information
SKU :
2507S
Product-Name :
PSD95 Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R
Applications :
Immunofluorescence (Frozen)
Product-Category :
Neuroscience
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
95
Host :
Rabbit
Target :
PSD-95
Primary-Protein :
PSD-95
Alt-Names :
DLG4,Disks large homolog 4,FLJ97752,FLJ98574,PSD-95,PSD95,Postsynaptic density protein 95,SAP-90,SAP90,Synapse-associated protein 90,Tax interaction protein 15,discs large homolog 4,discs, large homolog 4 (Drosophila),post-synaptic density protein 95
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.