| Published Application/Species/Dilution | Reference |
|---|
- immunocytochemistry; human; fig s2
- western blot; human; fig s2
| Chen X, Ji Z, Webber A, Sharrocks A. Genome-wide binding studies reveal DNA binding specificity mechanisms and functional interplay amongst Forkhead transcription factors. Nucleic Acids Res. 2016;44:1566-78 pubmed publisher |
- western blot; mouse; fig 3
| Nwadozi E, Roudier E, Rullman E, Tharmalingam S, Liu H, Gustafsson T, et al. Endothelial FoxO proteins impair insulin sensitivity and restrain muscle angiogenesis in response to a high-fat diet. FASEB J. 2016;: pubmed |
- western blot; mouse; fig 6
| Martinelli G, Olivari D, Re Cecconi A, Talamini L, Ottoboni L, Lecker S, et al. Activation of the SDF1/CXCR4 pathway retards muscle atrophy during cancer cachexia. Oncogene. 2016;: pubmed publisher |
- immunocytochemistry; human; fig 5
| Ahn J, Li J, Chen E, Kent D, Park H, Green A. JAK2V617F mediates resistance to DNA damage-induced apoptosis by modulating FOXO3A localization and Bcl-xL deamidation. Oncogene. 2016;35:2235-46 pubmed publisher |
| Huang C, Wang T, Tung Y, Lin W. Effect of Exercise Training on Skeletal Muscle SIRT1 and PGC-1α Expression Levels in Rats of Different Age. Int J Med Sci. 2016;13:260-70 pubmed publisher |
| Verma R, Marchese A. The endosomal sorting complex required for transport pathway mediates chemokine receptor CXCR4-promoted lysosomal degradation of the mammalian target of rapamycin antagonist DEPTOR. J Biol Chem. 2015;290:6810-24 pubmed publisher |
- western blot; mouse; 1:1000; fig 7
| Tontonoz P, Cortez-Toledo O, Wroblewski K, Hong C, Lim L, Carranza R, et al. The orphan nuclear receptor Nur77 is a determinant of myofiber size and muscle mass in mice. Mol Cell Biol. 2015;35:1125-38 pubmed publisher |
| Cho S, Cho M, Kim J, Kaeberlein M, Lee S, Suh Y. Syringaresinol protects against hypoxia/reoxygenation-induced cardiomyocytes injury and death by destabilization of HIF-1α in a FOXO3-dependent mechanism. Oncotarget. 2015;6:43-55 pubmed |
- immunocytochemistry; rat; fig 5
- western blot; rat; fig 3
| Zhang Z, Zhang T, Zhou Y, Wei X, Zhu J, Zhang J, et al. Activated phosphatidylinositol 3-kinase/Akt inhibits the transition of endothelial progenitor cells to mesenchymal cells by regulating the forkhead box subgroup O-3a signaling. Cell Physiol Biochem. 2015;35:1643-53 pubmed publisher |
- western blot; mouse
- western blot; rat
| Zeldich E, Chen C, Colvin T, Bove-Fenderson E, Liang J, Tucker Zhou T, et al. The neuroprotective effect of Klotho is mediated via regulation of members of the redox system. J Biol Chem. 2014;289:24700-15 pubmed publisher |
- western blot; mouse; 1:1000
| Zhang Y, Zhang X, Gao L, Liu Y, Jiang D, Chen K, et al. Growth/differentiation factor 1 alleviates pressure overload-induced cardiac hypertrophy and dysfunction. Biochim Biophys Acta. 2014;1842:232-44 pubmed publisher |
| Coomans de Brachène A, Bollaert E, Eijkelenboom A, de Rocca Serra A, van der Vos K, Burgering B, et al. The expression of the tumour suppressor HBP1 is down-regulated by growth factors via the PI3K/PKB/FOXO pathway. Biochem J. 2014;460:25-34 pubmed publisher |
- western blot; human; 1:1000
| Tanaka T, Iino M. Knockdown of Sec8 promotes cell-cycle arrest at G1/S phase by inducing p21 via control of FOXO proteins. FEBS J. 2014;281:1068-84 pubmed publisher |
- western blot; mouse; 1:500
| E L, Burns J, Swerdlow R. Effect of high-intensity exercise on aged mouse brain mitochondria, neurogenesis, and inflammation. Neurobiol Aging. 2014;35:2574-83 pubmed publisher |
| Exil V, Ping L, Yu Y, Chakraborty S, Caito S, Wells K, et al. Activation of MAPK and FoxO by manganese (Mn) in rat neonatal primary astrocyte cultures. PLoS ONE. 2014;9:e94753 pubmed publisher |
| Manley S, Ni H, Williams J, Kong B, DiTacchio L, Guo G, et al. Farnesoid X receptor regulates forkhead Box O3a activation in ethanol-induced autophagy and hepatotoxicity. Redox Biol. 2014;2:991-1002 pubmed publisher |
- immunoprecipitation; human; fig 2a
- western blot; human; fig 2a
- western blot; mouse; fig 3a
| Zheng X, Zhai B, Koivunen P, Shin S, Lu G, Liu J, et al. Prolyl hydroxylation by EglN2 destabilizes FOXO3a by blocking its interaction with the USP9x deubiquitinase. Genes Dev. 2014;28:1429-44 pubmed publisher |
- immunohistochemistry - frozen section; mouse; 1:200
- western blot; mouse
| Ni H, Bhakta A, Wang S, Li Z, Manley S, Huang H, et al. Role of hypoxia inducing factor-1β in alcohol-induced autophagy, steatosis and liver injury in mice. PLoS ONE. 2014;9:e115849 pubmed publisher |
- immunocytochemistry; human
- western blot; mouse
| Tumurbaatar B, Tikhanovich I, Li Z, Ren J, Ralston R, Kuravi S, et al. Hepatitis C and alcohol exacerbate liver injury by suppression of FOXO3. Am J Pathol. 2013;183:1803-14 pubmed publisher |
| Luo L, Lu A, Wang Y, Hong A, Chen Y, Hu J, et al. Chronic resistance training activates autophagy and reduces apoptosis of muscle cells by modulating IGF-1 and its receptors, Akt/mTOR and Akt/FOXO3a signaling in aged rats. Exp Gerontol. 2013;48:427-36 pubmed publisher |
- immunocytochemistry; mouse
| McGowan S, McCoy D. Platelet-derived growth factor-A regulates lung fibroblast S-phase entry through p27(kip1) and FoxO3a. Respir Res. 2013;14:68 pubmed publisher |
- immunohistochemistry - frozen section; mouse
- immunocytochemistry; mouse
- western blot; mouse
| Ni H, Du K, You M, Ding W. Critical role of FoxO3a in alcohol-induced autophagy and hepatotoxicity. Am J Pathol. 2013;183:1815-25 pubmed publisher |
| Dai J, Shen D, Bian Z, Zhou H, Gan H, Zong J, et al. IKKi deficiency promotes pressure overload-induced cardiac hypertrophy and fibrosis. PLoS ONE. 2013;8:e53412 pubmed publisher |
| Huang Q, Gao B, Wang L, Zhang H, Li X, Shi J, et al. Ophiopogonin D: A new herbal agent against osteoporosis. Bone. 2015;74:18-28 pubmed publisher |
| Zhu W, Tong H, Teh J, Wang M. Forkhead box protein O3 transcription factor negatively regulates autophagy in human cancer cells by inhibiting forkhead box protein O1 expression and cytosolic accumulation. PLoS ONE. 2014;9:e115087 pubmed publisher |
| Tzelepis F, Joseph J, Haddad E, MacLean S, Dudani R, Agenes F, et al. Intrinsic role of FoxO3a in the development of CD8+ T cell memory. J Immunol. 2013;190:1066-75 pubmed publisher |
| Fujiki K, Inamura H, Matsuoka M. Phosphorylation of FOXO3a by PI3K/Akt pathway in HK-2 renal proximal tubular epithelial cells exposed to cadmium. Arch Toxicol. 2013;87:2119-27 pubmed publisher |
| Benhenda S, Ducroux A, Rivière L, Sobhian B, Ward M, Dion S, et al. Methyltransferase PRMT1 is a binding partner of HBx and a negative regulator of hepatitis B virus transcription. J Virol. 2013;87:4360-71 pubmed publisher |
| Ogawa M, Kariya Y, Kitakaze T, Yamaji R, Harada N, Sakamoto T, et al. The preventive effect of β-carotene on denervation-induced soleus muscle atrophy in mice. Br J Nutr. 2013;109:1349-58 pubmed publisher |
| Bentzinger C, Lin S, Romanino K, Castets P, Guridi M, Summermatter S, et al. Differential response of skeletal muscles to mTORC1 signaling during atrophy and hypertrophy. Skelet Muscle. 2013;3:6 pubmed publisher |
| Sykes S, Lane S, Bullinger L, Kalaitzidis D, Yusuf R, Saez B, et al. AKT/FOXO signaling enforces reversible differentiation blockade in myeloid leukemias. Cell. 2011;146:697-708 pubmed publisher |
| Wang X, Wu Y, Tan L, Tian Z, Liu J, Zhu D, et al. Follicle-stimulating hormone regulates pro-apoptotic protein Bcl-2-interacting mediator of cell death-extra long (BimEL)-induced porcine granulosa cell apoptosis. J Biol Chem. 2012;287:10166-77 pubmed publisher |
| Ochi E, Hirose T, Hiranuma K, Min S, Ishii N, Nakazato K. Elevation of myostatin and FOXOs in prolonged muscular impairment induced by eccentric contractions in rat medial gastrocnemius muscle. J Appl Physiol (1985). 2010;108:306-13 pubmed publisher |
| Dehner M, Hadjihannas M, Weiske J, Huber O, Behrens J. Wnt signaling inhibits Forkhead box O3a-induced transcription and apoptosis through up-regulation of serum- and glucocorticoid-inducible kinase 1. J Biol Chem. 2008;283:19201-10 pubmed publisher |
