product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
SirT1 (C14H4) Rabbit mAb
catalog :
2496
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
C14H4
reactivity :
human
application :
western blot, immunoprecipitation
citations: 6
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; fig 4e
Monteagudo S, Cornelis F, Aznar López C, Yibmantasiri P, Guns L, Carmeliet P, et al. DOT1L safeguards cartilage homeostasis and protects against osteoarthritis. Nat Commun. 2017;8:15889 pubmed publisher
  • western blot; human; loading ...; fig 2c
Shen X, Wang M, Bi X, Zhang J, Wen S, Fu G, et al. Resveratrol prevents endothelial progenitor cells from senescence and reduces the oxidative reaction via PPAR??/HO?1 pathways. Mol Med Rep. 2016;14:5528-5534 pubmed publisher
  • western blot; human; fig s1
Tsai S, Huang P, Hsu Y, Peng Y, Lee C, Wang J, et al. Inhibition of hypoxia inducible factor-1α attenuates abdominal aortic aneurysm progression through the down-regulation of matrix metalloproteinases. Sci Rep. 2016;6:28612 pubmed publisher
  • western blot; human; fig 2
Kim J, Kim B, Lee H, Thakkar S, Babbitt D, Eguchi S, et al. Shear stress-induced mitochondrial biogenesis decreases the release of microparticles from endothelial cells. Am J Physiol Heart Circ Physiol. 2015;309:H425-33 pubmed publisher
Keir L, Firth R, Aponik L, Feitelberg D, Sakimoto S, Aguilar E, et al. VEGF regulates local inhibitory complement proteins in the eye and kidney. J Clin Invest. 2017;127:199-214 pubmed publisher
Borrego Diaz E, Powers B, Azizov V, Lovell S, Reyes R, Chapman B, et al. A potential regulatory loop between Lin28B:miR‑212 in androgen-independent prostate cancer. Int J Oncol. 2014;45:2421-9 pubmed publisher
product information
SKU :
2496S
Product-Name :
SirT1 (C14H4) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H
Applications :
Immunoprecipitation
Product-Category :
Chromatin Regulation / Nuclear Function
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
120
Host :
Rabbit
Target :
SirT1
Primary-Protein :
SIRT1
Alt-Names :
NAD-dependent deacetylase sirtuin-1,SIR2-like protein 1,SIR2L1,SIR2alpha,SIRT1,hSIR2,hSIRT1,sir2-like 1,sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae),sirtuin 1,sirtuin type 1
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.