product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
VEGF Receptor 2 (55B11) Rabbit mAb
catalog :
2479S
quantity :
100 ul
price :
235 USD
clonality :
monoclonal
host :
rabbit
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry
citations: 31
Published Application/Species/DilutionReference
  • western blot; mouse; 1:1000; fig s5b
He W, Bai G, Zhou H, Wei N, White N, Lauer J, et al. CMT2D neuropathy is linked to the neomorphic binding activity of glycyl-tRNA synthetase. Nature. 2015;526:710-4 pubmed publisher
  • western blot; human
Sivaraj K, Li R, Albarrán-Juárez J, Wang S, Tischner D, Grimm M, et al. Endothelial Gαq/11 is required for VEGF-induced vascular permeability and angiogenesis. Cardiovasc Res. 2015;108:171-80 pubmed publisher
  • immunocytochemistry; human; 1:300
Takasato M, Er P, Chiu H, Maier B, Baillie G, Ferguson C, et al. Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis. Nature. 2015;526:564-8 pubmed publisher
  • western blot; mouse
Majumder A, Syed K, Joseph S, Scambler P, Dutta D. Histone Chaperone HIRA in Regulation of Transcription Factor RUNX1. J Biol Chem. 2015;290:13053-63 pubmed publisher
  • immunohistochemistry; mouse; 1:500; fig 8
Shi X, Zirbes K, Rasmussen T, Ferdous A, Garry M, Koyano-Nakagawa N, et al. The transcription factor Mesp1 interacts with cAMP-responsive element binding protein 1 (Creb1) and coactivates Ets variant 2 (Etv2) gene expression. J Biol Chem. 2015;290:9614-25 pubmed publisher
  • immunohistochemistry; human; 1:100
Hamdollah Zadeh M, Amin E, Hoareau-Aveilla C, Domingo E, Symonds K, Ye X, et al. Alternative splicing of TIA-1 in human colon cancer regulates VEGF isoform expression, angiogenesis, tumour growth and bevacizumab resistance. Mol Oncol. 2015;9:167-78 pubmed publisher
  • western blot; rat; 1:750
Ozmen A, Unek G, Kipmen-Korgun D, Cetinkaya B, Avcil Z, Korgun E. Glucocorticoid exposure altered angiogenic factor expression via Akt/mTOR pathway in rat placenta. Ann Anat. 2015;198:34-40 pubmed publisher
  • western blot; mouse; fig 7
Aggarwal P, Veron D, Thomas D, Siegel D, Moeckel G, Kashgarian M, et al. Semaphorin3a promotes advanced diabetic nephropathy. Diabetes. 2015;64:1743-59 pubmed publisher
  • western blot; mouse; 1:1000
Jing L, Li S, Li Q. Akt/hypoxia-inducible factor-1α signaling deficiency compromises skin wound healing in a type 1 diabetes mouse model. Exp Ther Med. 2015;9:2141-2146 pubmed
  • western blot; human
Kim B, Lee J, Choi J, Park D, Song H, Park T, et al. Imidazole-based alkaloid derivative LCB54-0009 suppresses ocular angiogenesis and lymphangiogenesis in models of experimental retinopathy and corneal neovascularization. Br J Pharmacol. 2015;172:3875-89 pubmed publisher
  • western blot; human
Coon B, Baeyens N, Han J, Budatha M, Ross T, Fang J, et al. Intramembrane binding of VE-cadherin to VEGFR2 and VEGFR3 assembles the endothelial mechanosensory complex. J Cell Biol. 2015;208:975-86 pubmed publisher
  • immunohistochemistry; human; 1:150
Knösel T, Werner M, Jung A, Kirchner T, Dürr H. Dedifferentiated chondrosarcoma mimicking a giant cell tumor. Is this low grade dedifferentiated chondrosarcoma?. Pathol Res Pract. 2014;210:194-7 pubmed publisher
  • immunocytochemistry; human
Pryzhkova M, Aria I, Cheng Q, Harris G, Zan X, Gharib M, et al. Carbon nanotube-based substrates for modulation of human pluripotent stem cell fate. Biomaterials. 2014;35:5098-109 pubmed publisher
  • western blot; rat; 1:500; fig 5
Scotti L, Abramovich D, Pascuali N, Irusta G, Meresman G, Tesone M, et al. Local VEGF inhibition prevents ovarian alterations associated with ovarian hyperstimulation syndrome. J Steroid Biochem Mol Biol. 2014;144:392-401 pubmed publisher
  • western blot; human
Chen P, Qin L, Zhuang Z, Tellides G, Lax I, Schlessinger J, et al. The docking protein FRS2α is a critical regulator of VEGF receptors signaling. Proc Natl Acad Sci U S A. 2014;111:5514-9 pubmed publisher
  • immunohistochemistry; human; 1:100
Styring E, Seinen J, Dominguez-Valentin M, Domanski H, Jonsson M, von Steyern F, et al. Key roles for MYC, KIT and RET signaling in secondary angiosarcomas. Br J Cancer. 2014;111:407-12 pubmed publisher
Planeix F, Siraj M, Bidard F, Robin B, Pichon C, Sastre-Garau X, et al. Endothelial follicle-stimulating hormone receptor expression in invasive breast cancer and vascular remodeling at tumor periphery. J Exp Clin Cancer Res. 2015;34:12 pubmed publisher
Friedman A, Amzallag A, Pruteanu-Malinici I, Baniya S, Cooper Z, Piris A, et al. Landscape of Targeted Anti-Cancer Drug Synergies in Melanoma Identifies a Novel BRAF-VEGFR/PDGFR Combination Treatment. PLoS ONE. 2015;10:e0140310 pubmed publisher
Kere M, Siriboon C, Liao J, Lo N, Chiang H, Fan Y, et al. Vascular endothelial growth factor A improves quality of matured porcine oocytes and developing parthenotes. Domest Anim Endocrinol. 2014;49:60-9 pubmed publisher
Hu X, Zhang J, Xu B, Jiang Z, Ragaz J, Tong Z, et al. Multicenter phase II study of apatinib, a novel VEGFR inhibitor in heavily pretreated patients with metastatic triple-negative breast cancer. Int J Cancer. 2014;135:1961-9 pubmed publisher
Fan M, Zhang J, Wang Z, Wang B, Zhang Q, Zheng C, et al. Phosphorylated VEGFR2 and hypertension: potential biomarkers to indicate VEGF-dependency of advanced breast cancer in anti-angiogenic therapy. Breast Cancer Res Treat. 2014;143:141-51 pubmed publisher
Guerin O, Etienne-Grimaldi M, Monteverde M, Sudaka A, Brunstein M, Formento P, et al. Contrasted effects of the multitarget TKi vandetanib on docetaxel-sensitive and docetaxel-resistant prostate cancer cell lines. Urol Oncol. 2013;31:1567-75 pubmed publisher
Tiwari A, Jung J, Inamdar S, Nihalani D, Choudhury A. The myosin motor Myo1c is required for VEGFR2 delivery to the cell surface and for angiogenic signaling. Am J Physiol Heart Circ Physiol. 2013;304:H687-96 pubmed publisher
Liu F, Kang I, Park C, Chang L, Wang W, Lee D, et al. ER71 specifies Flk-1+ hemangiogenic mesoderm by inhibiting cardiac mesoderm and Wnt signaling. Blood. 2012;119:3295-305 pubmed publisher
Zhang L, Lü L, Chan W, Huang Y, Wai M, Yew D. Effects of DL-3-n-butylphthalide on vascular dementia and angiogenesis. Neurochem Res. 2012;37:911-9 pubmed publisher
Curradi G, Walters M, Ding B, Rafii S, Hackett N, Crystal R. Airway basal cell vascular endothelial growth factor-mediated cross-talk regulates endothelial cell-dependent growth support of human airway basal cells. Cell Mol Life Sci. 2012;69:2217-31 pubmed publisher
Sugimoto K, Moriyasu F, Negishi Y, Hamano N, Oshiro H, Rognin N, et al. Quantification in molecular ultrasound imaging: a comparative study in mice between healthy liver and a human hepatocellular carcinoma xenograft. J Ultrasound Med. 2012;31:1909-16 pubmed
Akiyama K, Ohga N, Hida Y, Kawamoto T, Sadamoto Y, Ishikawa S, et al. Tumor endothelial cells acquire drug resistance by MDR1 up-regulation via VEGF signaling in tumor microenvironment. Am J Pathol. 2012;180:1283-93 pubmed publisher
Napione L, Pavan S, Veglio A, Picco A, Boffetta G, Celani A, et al. Unraveling the influence of endothelial cell density on VEGF-A signaling. Blood. 2012;119:5599-607 pubmed publisher
Antonescu C, Yoshida A, Guo T, Chang N, Zhang L, Agaram N, et al. KDR activating mutations in human angiosarcomas are sensitive to specific kinase inhibitors. Cancer Res. 2009;69:7175-9 pubmed publisher
Vader P, Crielaard B, van Dommelen S, van der Meel R, Storm G, Schiffelers R. Targeted delivery of small interfering RNA to angiogenic endothelial cells with liposome-polycation-DNA particles. J Control Release. 2012;160:211-6 pubmed publisher
product information
SKU :
2479S
Product-Name :
VEGF Receptor 2 (55B11) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M
Applications :
Immunofluorescence (Immunocytochemistry)
Product-Category :
RTK
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
210, 230
Host :
Rabbit
Target :
VEGFR2
Primary-Protein :
VEGFR-2
Alt-Names :
CD309,FLK-1,FLK1,Fetal liver kinase 1,KDR,Kinase insert domain receptor,Protein-tyrosine kinase receptor flk-1,VEGFR,VEGFR-2,VEGFR2,VGFR2,Vascular endothelial growth factor receptor 2,fetal liver kinase-1,kinase insert domain receptor (a type III receptor tyrosine kinase),soluble VEGFR2,tyrosine kinase growth factor receptor
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.