product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
VEGF Receptor 2 (55B11) Rabbit mAb
catalog :
2479
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
55B11
reactivity :
human, mouse, rat, rhesus macaque
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, reverse phase protein lysate microarray, other
citations: 141
Published Application/Species/Sample/DilutionReference
  • western blot; human; fig 5d
Lee J, Hur J, Kwon Y, Chae C, Choi J, Hwang I, et al. KAI1(CD82) is a key molecule to control angiogenesis and switch angiogenic milieu to quiescent state. J Hematol Oncol. 2021;14:148 pubmed publisher
  • western blot; human; 1:1000; fig 5e
Ma S, Mangala L, Hu W, Bayaktar E, Yokoi A, Hu W, et al. CD63-mediated cloaking of VEGF in small extracellular vesicles contributes to anti-VEGF therapy resistance. Cell Rep. 2021;36:109549 pubmed publisher
  • immunohistochemistry - frozen section; mouse; loading ...; fig 6
Hu J, Zhu M, Li D, Wu Q, Le Y. VEGF as a Direct Functional Regulator of Photoreceptors and Contributing Factor to Diabetes-Induced Alteration of Photoreceptor Function. Biomolecules. 2021;11: pubmed publisher
  • immunohistochemistry; mouse; 1:200; loading ...
He B, Chen P, Zambrano S, Dabaghie D, Hu Y, Möller Hackbarth K, et al. Single-cell RNA sequencing reveals the mesangial identity and species diversity of glomerular cell transcriptomes. Nat Commun. 2021;12:2141 pubmed publisher
  • western blot; mouse; loading ...; fig 6e
Tirronen A, Downes N, Huusko J, Laakkonen J, Tuomainen T, Tavi P, et al. The Ablation of VEGFR-1 Signaling Promotes Pressure Overload-Induced Cardiac Dysfunction and Sudden Death. Biomolecules. 2021;11: pubmed publisher
  • western blot; mouse; 1:500; loading ...; fig 3c
Harde E, Nicholson L, Furones Cuadrado B, Bissen D, Wigge S, Urban S, et al. EphrinB2 regulates VEGFR2 during dendritogenesis and hippocampal circuitry development. elife. 2019;8: pubmed publisher
  • western blot; mouse; 1:1000; loading ...
  • western blot; human; 1:1000; loading ...
Luck R, Urban S, Karakatsani A, Harde E, Sambandan S, Nicholson L, et al. VEGF/VEGFR2 signaling regulates hippocampal axon branching during development. elife. 2019;8: pubmed publisher
  • western blot; human; loading ...; fig s4t
Xu M, Xu H, Lin Y, Sun X, Wang L, Fang Z, et al. LECT2, a Ligand for Tie1, Plays a Crucial Role in Liver Fibrogenesis. Cell. 2019;178:1478-1492.e20 pubmed publisher
  • immunohistochemistry; human; fig 5h
  • western blot; human; fig 5c
Njah K, Chakraborty S, Qiu B, Arumugam S, Raju A, Pobbati A, et al. A Role of Agrin in Maintaining the Stability of Vascular Endothelial Growth Factor Receptor-2 during Tumor Angiogenesis. Cell Rep. 2019;28:949-965.e7 pubmed publisher
  • western blot; human; 1:2000; loading ...; fig 8a
  • western blot; mouse; 1:2000; loading ...; fig 8b
Zhang S, Liu W, Yang Y, Sun K, Li S, Xu H, et al. Tmem30a Deficiency in endothelial cells impairs cell proliferation and angiogenesis. J Cell Sci. 2019;: pubmed publisher
  • immunoprecipitation; rhesus macaque; 1:100; loading ...; fig 1c
  • western blot; rhesus macaque; 1:1000; loading ...; fig 1c
Hayashi H, Mamun A, Takeyama M, Yamamura A, Zako M, Yagasaki R, et al. Activator of G-protein signaling 8 is involved in VEGF-induced choroidal neovascularization. Sci Rep. 2019;9:1560 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 2e
Urner S, Planas Paz L, Hilger L, Henning C, Branopolski A, Kelly Goss M, et al. Identification of ILK as a critical regulator of VEGFR3 signalling and lymphatic vascular growth. EMBO J. 2019;38: pubmed publisher
  • immunoprecipitation; human; fig 2a
  • western blot; human; 1:1000; fig 2a
Segarra M, Aburto M, Cop F, Llaó Cid C, Härtl R, Damm M, et al. Endothelial Dab1 signaling orchestrates neuro-glia-vessel communication in the central nervous system. Science. 2018;361: pubmed publisher
  • immunohistochemistry - frozen section; rat; loading ...; fig 6a
Beazley Long N, Moss C, Ashby W, Bestall S, Almahasneh F, Durrant A, et al. VEGFR2 promotes central endothelial activation and the spread of pain in inflammatory arthritis. Brain Behav Immun. 2018;74:49-67 pubmed publisher
  • other; human; loading ...; fig 4c
Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  • western blot; human; loading ...; fig 8b
Yin R, Guo L, Gu J, Li C, Zhang W. Over expressing miR-19b-1 suppress breast cancer growth by inhibiting tumor microenvironment induced angiogenesis. Int J Biochem Cell Biol. 2018;97:43-51 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig s8a
Polacheck W, Kutys M, Yang J, Eyckmans J, Wu Y, Vasavada H, et al. A non-canonical Notch complex regulates adherens junctions and vascular barrier function. Nature. 2017;552:258-262 pubmed publisher
  • western blot; human; loading ...; fig 8c
Kim J, Kim Y, Kim J, Park D, Bae H, Lee D, et al. YAP/TAZ regulates sprouting angiogenesis and vascular barrier maturation. J Clin Invest. 2017;127:3441-3461 pubmed publisher
  • reverse phase protein lysate microarray; human; loading ...; fig st6
Cherniack A, Shen H, Walter V, Stewart C, Murray B, Bowlby R, et al. Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell. 2017;31:411-423 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 1a
Yang G, Zhao Z, Qin T, Wang D, Chen L, Xiang R, et al. TNFSF15 inhibits VEGF-stimulated vascular hyperpermeability by inducing VEGFR2 dephosphorylation. FASEB J. 2017;31:2001-2012 pubmed publisher
  • reverse phase protein lysate microarray; human; loading ...; fig 3a
. Integrated genomic and molecular characterization of cervical cancer. Nature. 2017;543:378-384 pubmed publisher
  • immunocytochemistry; mouse; fig 3i
Maltabe V, Barka E, Kontonika M, Florou D, Kouvara Pritsouli M, Roumpi M, et al. Isolation of an ES-Derived Cardiovascular Multipotent Cell Population Based on VE-Cadherin Promoter Activity. Stem Cells Int. 2016;2016:8305624 pubmed publisher
  • western blot; human; fig 5c
Indrakusuma I, Romacho T, Eckel J. Protease-Activated Receptor 2 Promotes Pro-Atherogenic Effects through Transactivation of the VEGF Receptor 2 in Human Vascular Smooth Muscle Cells. Front Pharmacol. 2016;7:497 pubmed publisher
  • immunoprecipitation; mouse; loading ...; fig 5d
  • immunoprecipitation; human; loading ...; fig 5c
  • western blot; human; loading ...; fig 4a
Wu Q, Ma Y, Ruan C, Yang Y, Liu X, Ge Q, et al. Loss of osteoglycin promotes angiogenesis in limb ischaemia mouse models via modulation of vascular endothelial growth factor and vascular endothelial growth factor receptor 2 signalling pathway. Cardiovasc Res. 2017;113:70-80 pubmed publisher
  • western blot; human; loading ...
Hill S, Nesser N, Johnson Camacho K, Jeffress M, Johnson A, Boniface C, et al. Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling. Cell Syst. 2017;4:73-83.e10 pubmed publisher
  • western blot; human; loading ...; fig s7c
  • immunohistochemistry - frozen section; mouse; loading ...; fig s5c
  • western blot; mouse; loading ...; fig 3i
Lee S, Rho S, Park H, Park J, Kim J, Lee I, et al. Carbohydrate-binding protein CLEC14A regulates VEGFR-2- and VEGFR-3-dependent signals during angiogenesis and lymphangiogenesis. J Clin Invest. 2017;127:457-471 pubmed publisher
  • immunoprecipitation; mouse; loading ...; fig 3a
  • western blot; mouse; loading ...; fig 3a
Ganta V, Choi M, Kutateladze A, Annex B. VEGF165b Modulates Endothelial VEGFR1-STAT3 Signaling Pathway and Angiogenesis in Human and Experimental Peripheral Arterial Disease. Circ Res. 2017;120:282-295 pubmed publisher
  • western blot; human; loading ...; fig 5
Galoian K, Luo S, Qureshi A, Patel P, Price R, Morse A, et al. Effect of cytostatic proline rich polypeptide-1 on tumor suppressors of inflammation pathway signaling in chondrosarcoma. Mol Clin Oncol. 2016;5:618-624 pubmed
  • western blot; human; loading ...; fig 1d
Wang S, Chennupati R, Kaur H, Iring A, Wettschureck N, Offermanns S. Endothelial cation channel PIEZO1 controls blood pressure by mediating flow-induced ATP release. J Clin Invest. 2016;126:4527-4536 pubmed publisher
  • western blot; human; loading ...; fig 7a
Xin H, ZHONG C, Nudleman E, Ferrara N. Evidence for Pro-angiogenic Functions of VEGF-Ax. Cell. 2016;167:275-284.e6 pubmed publisher
  • western blot; mouse; 1:1000; fig 1
Yang Y, Zhang Y, Iwamoto H, Hosaka K, Seki T, Andersson P, et al. Discontinuation of anti-VEGF cancer therapy promotes metastasis through a liver revascularization mechanism. Nat Commun. 2016;7:12680 pubmed publisher
  • western blot; human; 1:1000; fig s4e
Jenny Zhou H, Qin L, Zhang H, Tang W, Ji W, He Y, et al. Endothelial exocytosis of angiopoietin-2 resulting from CCM3 deficiency contributes to cerebral cavernous malformation. Nat Med. 2016;22:1033-1042 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:50; loading ...; tbl 2
Peckova K, Michal M, Hadravsky L, Suster S, Damjanov I, Miesbauerova M, et al. Littoral cell angioma of the spleen: a study of 25 cases with confirmation of frequent association with visceral malignancies. Histopathology. 2016;69:762-774 pubmed publisher
  • western blot; human; fig 4
Lock R, Ingraham R, Maertens O, Miller A, Weledji N, Legius E, et al. Cotargeting MNK and MEK kinases induces the regression of NF1-mutant cancers. J Clin Invest. 2016;126:2181-90 pubmed publisher
  • immunohistochemistry; human; loading ...; fig 1
de Geus S, Boogerd L, Swijnenburg R, Mieog J, Tummers W, Prevoo H, et al. Selecting Tumor-Specific Molecular Targets in Pancreatic Adenocarcinoma: Paving the Way for Image-Guided Pancreatic Surgery. Mol Imaging Biol. 2016;18:807-819 pubmed
  • immunohistochemistry - paraffin section; human; loading ...; fig s1o
Krampitz G, George B, Willingham S, Volkmer J, Weiskopf K, Jahchan N, et al. Identification of tumorigenic cells and therapeutic targets in pancreatic neuroendocrine tumors. Proc Natl Acad Sci U S A. 2016;113:4464-9 pubmed publisher
  • western blot; mouse; fig 5
Nishida Fukuda H, Araki R, Shudou M, Okazaki H, Tomono Y, Nakayama H, et al. Ectodomain Shedding of Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE-1) Is Induced by Vascular Endothelial Growth Factor A (VEGF-A). J Biol Chem. 2016;291:10490-500 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 4a
Jung O, Trapp Stamborski V, Purushothaman A, Jin H, Wang H, Sanderson R, et al. Heparanase-induced shedding of syndecan-1/CD138 in myeloma and endothelial cells activates VEGFR2 and an invasive phenotype: prevention by novel synstatins. Oncogenesis. 2016;5:e202 pubmed publisher
  • immunohistochemistry - paraffin section; human; loading ...; fig 5n
Sato T, Paquet Fifield S, Harris N, Roufail S, Turner D, Yuan Y, et al. VEGF-D promotes pulmonary oedema in hyperoxic acute lung injury. J Pathol. 2016;239:152-61 pubmed publisher
  • western blot; human; fig 6
Wu G, Zeng G. METCAM/MUC18 is a novel tumor and metastasis suppressor for the human ovarian cancer SKOV3 cells. BMC Cancer. 2016;16:136 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100; loading ...
  • western blot; human; 1:1000
Alonso F, Domingos Pereira S, Le Gal L, Derré L, Meda P, Jichlinski P, et al. Targeting endothelial connexin40 inhibits tumor growth by reducing angiogenesis and improving vessel perfusion. Oncotarget. 2016;7:14015-28 pubmed publisher
  • flow cytometry; human; fig 5
  • immunoprecipitation; human; fig 7
  • immunocytochemistry; human; fig 6
Hayashi H, Al Mamun A, Sakima M, Sato M. Activator of G-protein signaling 8 is involved in VEGF-mediated signal processing during angiogenesis. J Cell Sci. 2016;129:1210-22 pubmed publisher
  • western blot; human; loading ...; fig 4a
Derangère V, Fumet J, Boidot R, Bengrine L, Limagne E, Chevriaux A, et al. Does bevacizumab impact anti-EGFR therapy efficacy in metastatic colorectal cancer?. Oncotarget. 2016;7:9309-21 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 4
Rusckowski M, Wang Y, Blankenberg F, Levashova Z, Backer M, Backer J. Targeted scVEGF/(177)Lu radiopharmaceutical inhibits growth of metastases and can be effectively combined with chemotherapy. EJNMMI Res. 2016;6:4 pubmed publisher
  • western blot; rat; 1:200; fig 2
Szulcek R, Happé C, Rol N, Fontijn R, Dickhoff C, Hartemink K, et al. Delayed Microvascular Shear Adaptation in Pulmonary Arterial Hypertension. Role of Platelet Endothelial Cell Adhesion Molecule-1 Cleavage. Am J Respir Crit Care Med. 2016;193:1410-20 pubmed publisher
  • western blot; human; 1:5000; loading ...
Ulrich F, Carretero Ortega J, Menendez J, Narvaez C, Sun B, Lancaster E, et al. Reck enables cerebrovascular development by promoting canonical Wnt signaling. Development. 2016;143:147-59 pubmed publisher
  • western blot; mouse; 1:500; fig 2a
  • western blot; human; 1:500; fig 2a
Koudelkova P, Weber G, Mikulits W. Liver Sinusoidal Endothelial Cells Escape Senescence by Loss of p19ARF. PLoS ONE. 2015;10:e0142134 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 1a
Taïeb D, Barlier A, Yang C, Pertuit M, Tchoghandjian A, Rochette C, et al. Somatic gain-of-function HIF2A mutations in sporadic central nervous system hemangioblastomas. J Neurooncol. 2016;126:473-81 pubmed publisher
  • western blot; mouse; 1:1000; fig s5b
He W, Bai G, Zhou H, Wei N, White N, Lauer J, et al. CMT2D neuropathy is linked to the neomorphic binding activity of glycyl-tRNA synthetase. Nature. 2015;526:710-4 pubmed publisher
  • immunohistochemistry; rat; 1:500; loading ...; fig 7a
Nakano A, Nakahara T, Mori A, Ushikubo H, Sakamoto K, Ishii K. Short-term treatment with VEGF receptor inhibitors induces retinopathy of prematurity-like abnormal vascular growth in neonatal rats. Exp Eye Res. 2016;143:120-31 pubmed publisher
  • immunocytochemistry; human; 1:300
Takasato M, Er P, Chiu H, Maier B, Baillie G, Ferguson C, et al. Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis. Nature. 2015;526:564-8 pubmed publisher
  • western blot; mouse; fig 3
Zhao C, Su Y, Zhang J, Feng Q, Qu L, Wang L, et al. Fibrinogen-derived fibrinostatin inhibits tumor growth through anti-angiogenesis. Cancer Sci. 2015;106:1596-606 pubmed publisher
  • western blot; human
Sivaraj K, Li R, Albarrán Juárez J, Wang S, Tischner D, Grimm M, et al. Endothelial Gαq/11 is required for VEGF-induced vascular permeability and angiogenesis. Cardiovasc Res. 2015;108:171-80 pubmed publisher
  • immunohistochemistry; mouse; 1:300
Regan J, Kannan P, Kemp M, Kramer B, Newnham J, Jobe A, et al. Damage-Associated Molecular Pattern and Fetal Membrane Vascular Injury and Collagen Disorganization in Lipopolysaccharide-Induced Intra-amniotic Inflammation in Fetal Sheep. Reprod Sci. 2016;23:69-80 pubmed publisher
  • western blot; mouse; 1:1000
Jing L, Li S, Li Q. Akt/hypoxia-inducible factor-1α signaling deficiency compromises skin wound healing in a type 1 diabetes mouse model. Exp Ther Med. 2015;9:2141-2146 pubmed
  • immunocytochemistry; human; fig 4
  • western blot; human; fig 4
Tate C, Mc Entire J, Pallini R, Vakana E, Wyss L, Blosser W, et al. A BMP7 Variant Inhibits Tumor Angiogenesis In Vitro and In Vivo through Direct Modulation of Endothelial Cell Biology. PLoS ONE. 2015;10:e0125697 pubmed publisher
  • western blot; human
Kim B, Lee J, Choi J, Park D, Song H, Park T, et al. Imidazole-based alkaloid derivative LCB54-0009 suppresses ocular angiogenesis and lymphangiogenesis in models of experimental retinopathy and corneal neovascularization. Br J Pharmacol. 2015;172:3875-89 pubmed publisher
  • western blot; human; loading ...; fig 3a
Liu L, Yu H, Huang X, Tan H, Li S, Luo Y, et al. A novel engineered VEGF blocker with an excellent pharmacokinetic profile and robust anti-tumor activity. BMC Cancer. 2015;15:170 pubmed publisher
  • western blot; mouse
Majumder A, Syed K, Joseph S, Scambler P, Dutta D. Histone Chaperone HIRA in Regulation of Transcription Factor RUNX1. J Biol Chem. 2015;290:13053-63 pubmed publisher
  • western blot; mouse; 1:500; fig 2
Lee I, Hüttemann M, Kruger A, Bollig Fischer A, Malek M. (-)-Epicatechin combined with 8 weeks of treadmill exercise is associated with increased angiogenic and mitochondrial signaling in mice. Front Pharmacol. 2015;6:43 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 5e
Salvucci O, Ohnuki H, Maric D, Hou X, Li X, Yoon S, et al. EphrinB2 controls vessel pruning through STAT1-JNK3 signalling. Nat Commun. 2015;6:6576 pubmed publisher
  • western blot; human; 1:200; tbl 4
  • immunohistochemistry - frozen section; mouse; 1:200; tbl 6
Chan N, He S, Spee C, Ishikawa K, Hinton D. Attenuation of choroidal neovascularization by histone deacetylase inhibitor. PLoS ONE. 2015;10:e0120587 pubmed publisher
  • western blot; human
Coon B, Baeyens N, Han J, Budatha M, Ross T, Fang J, et al. Intramembrane binding of VE-cadherin to VEGFR2 and VEGFR3 assembles the endothelial mechanosensory complex. J Cell Biol. 2015;208:975-86 pubmed publisher
  • immunohistochemistry; mouse; 1:500; fig 8
Shi X, Zirbes K, Rasmussen T, Ferdous A, Garry M, Koyano Nakagawa N, et al. The transcription factor Mesp1 interacts with cAMP-responsive element binding protein 1 (Creb1) and coactivates Ets variant 2 (Etv2) gene expression. J Biol Chem. 2015;290:9614-25 pubmed publisher
  • western blot; mouse; 1:1000; fig 5e
Choi S, Lee H, Choi J, Kim J, Park C, Joo H, et al. Cyclosporin A induces cardiac differentiation but inhibits hemato-endothelial differentiation of P19 cells. PLoS ONE. 2015;10:e0117410 pubmed publisher
  • immunocytochemistry; mouse; fig 2
Voron T, Colussi O, Marcheteau E, Pernot S, Nizard M, Pointet A, et al. VEGF-A modulates expression of inhibitory checkpoints on CD8+ T cells in tumors. J Exp Med. 2015;212:139-48 pubmed publisher
  • western blot; rat; 1:750
Ozmen A, Unek G, Kipmen Korgun D, Cetinkaya B, Avcil Z, Korgun E. Glucocorticoid exposure altered angiogenic factor expression via Akt/mTOR pathway in rat placenta. Ann Anat. 2015;198:34-40 pubmed publisher
  • western blot; mouse; fig 7
Aggarwal P, Veron D, Thomas D, Siegel D, Moeckel G, Kashgarian M, et al. Semaphorin3a promotes advanced diabetic nephropathy. Diabetes. 2015;64:1743-59 pubmed publisher
  • flow cytometry; human; loading ...; fig 5c
Guzmán E, Maers K, Roberts J, Kemami Wangun H, Harmody D, Wright A. The marine natural product microsclerodermin A is a novel inhibitor of the nuclear factor kappa B and induces apoptosis in pancreatic cancer cells. Invest New Drugs. 2015;33:86-94 pubmed publisher
  • immunohistochemistry; human; 1:100
Hamdollah Zadeh M, Amin E, Hoareau Aveilla C, Domingo E, Symonds K, Ye X, et al. Alternative splicing of TIA-1 in human colon cancer regulates VEGF isoform expression, angiogenesis, tumour growth and bevacizumab resistance. Mol Oncol. 2015;9:167-78 pubmed publisher
  • western blot; rat; 1:500; fig 5
Scotti L, Abramovich D, Pascuali N, Irusta G, Meresman G, Tesone M, et al. Local VEGF inhibition prevents ovarian alterations associated with ovarian hyperstimulation syndrome. J Steroid Biochem Mol Biol. 2014;144 Pt B:392-401 pubmed publisher
  • immunohistochemistry; human; 1:100
Styring E, Seinen J, Dominguez Valentin M, Domanski H, Jonsson M, von Steyern F, et al. Key roles for MYC, KIT and RET signaling in secondary angiosarcomas. Br J Cancer. 2014;111:407-12 pubmed publisher
  • western blot; human
Chen P, Qin L, Zhuang Z, Tellides G, Lax I, Schlessinger J, et al. The docking protein FRS2? is a critical regulator of VEGF receptors signaling. Proc Natl Acad Sci U S A. 2014;111:5514-9 pubmed publisher
  • immunocytochemistry; human
Pryzhkova M, Aria I, Cheng Q, Harris G, Zan X, Gharib M, et al. Carbon nanotube-based substrates for modulation of human pluripotent stem cell fate. Biomaterials. 2014;35:5098-109 pubmed publisher
  • immunohistochemistry; human; 1:150
Knösel T, Werner M, Jung A, Kirchner T, Dürr H. Dedifferentiated chondrosarcoma mimicking a giant cell tumor. Is this low grade dedifferentiated chondrosarcoma?. Pathol Res Pract. 2014;210:194-7 pubmed publisher
Bayliss A, Sundararaman A, Granet C, Mellor H. Raftlin is recruited by neuropilin-1 to the activated VEGFR2 complex to control proangiogenic signaling. Angiogenesis. 2020;23:371-383 pubmed publisher
Doronzo G, Astanina E, Cora D, Chiabotto G, Comunanza V, Noghero A, et al. TFEB controls vascular development by regulating the proliferation of endothelial cells. EMBO J. 2019;38: pubmed publisher
Ikeuchi T, de Vega S, Forcinito P, Doyle A, Amaral J, Rodriguez I, et al. Extracellular Protein Fibulin-7 and Its C-Terminal Fragment Have In Vivo Antiangiogenic Activity. Sci Rep. 2018;8:17654 pubmed publisher
Abou Faycal C, Brambilla E, Agorreta J, Lepeltier N, Jacquet T, Lemaître N, et al. The sVEGFR1-i13 splice variant regulates a β1 integrin/VEGFR autocrine loop involved in the progression and the response to anti-angiogenic therapies of squamous cell lung carcinoma. Br J Cancer. 2018;118:1596-1608 pubmed publisher
Ved N, Da Vitoria Lobo M, Bestall S, L Vidueira C, Beazley Long N, Ballmer Hofer K, et al. Diabetes-induced microvascular complications at the level of the spinal cord: a contributing factor in diabetic neuropathic pain. J Physiol. 2018;596:3675-3693 pubmed publisher
Busceti C, Marchitti S, Bianchi F, Di Pietro P, Riozzi B, Stanzione R, et al. Dickkopf-3 Upregulates VEGF in Cultured Human Endothelial Cells by Activating Activin Receptor-Like Kinase 1 (ALK1) Pathway. Front Pharmacol. 2017;8:111 pubmed publisher
Gong H, An S, Sassmann A, Liu M, Mastej V, Mittal M, et al. PAR1 Scaffolds TGF?RII to Downregulate TGF-? Signaling and Activate ESC Differentiation to Endothelial Cells. Stem Cell Reports. 2016;7:1050-1058 pubmed publisher
Faes S, Uldry E, Planche A, Santoro T, Pythoud C, Demartines N, et al. Acidic pH reduces VEGF-mediated endothelial cell responses by downregulation of VEGFR-2; relevance for anti-angiogenic therapies. Oncotarget. 2016;7:86026-86038 pubmed publisher
Zopf D, Fichtner I, Bhargava A, Steinke W, Thierauch K, Diefenbach K, et al. Pharmacologic activity and pharmacokinetics of metabolites of regorafenib in preclinical models. Cancer Med. 2016;5:3176-3185 pubmed publisher
Kumar R, Singh N, Rao G. Proline-rich tyrosine kinase 2 via enhancing signal transducer and activator of transcription 3-dependent cJun expression mediates retinal neovascularization. Sci Rep. 2016;6:26480 pubmed publisher
Sarabipour S, Ballmer Hofer K, Hristova K. VEGFR-2 conformational switch in response to ligand binding. elife. 2016;5:e13876 pubmed publisher
Rai D, Lawrence P, Kloc A, Schafer E, Rieder E. Analysis of the interaction between host factor Sam68 and viral elements during foot-and-mouth disease virus infections. Virol J. 2015;12:224 pubmed publisher
Vesci L, Milazzo F, Anastasi A, Petronzelli F, Chiapparino C, Carollo V, et al. Intra-tumor AvidinOX allows efficacy of low dose systemic biotinylated Cetuximab in a model of head and neck cancer. Oncotarget. 2016;7:914-28 pubmed publisher
Friedman A, Amzallag A, Pruteanu Malinici I, Baniya S, Cooper Z, Piris A, et al. Landscape of Targeted Anti-Cancer Drug Synergies in Melanoma Identifies a Novel BRAF-VEGFR/PDGFR Combination Treatment. PLoS ONE. 2015;10:e0140310 pubmed publisher
Tsai H, Huang S, Tsou M, Wang H, Chiu J. Role of Opioid Receptors Signaling in Remote Electrostimulation--Induced Protection against Ischemia/Reperfusion Injury in Rat Hearts. PLoS ONE. 2015;10:e0138108 pubmed publisher
Katzav S. Vav1: A Dr. Jekyll and Mr. Hyde protein--good for the hematopoietic system, bad for cancer. Oncotarget. 2015;6:28731-42 pubmed publisher
Ellison T, Atkinson S, Steri V, Kirkup B, Preedy M, Johnson R, et al. Suppression of β3-integrin in mice triggers a neuropilin-1-dependent change in focal adhesion remodelling that can be targeted to block pathological angiogenesis. Dis Model Mech. 2015;8:1105-19 pubmed publisher
Pfister N, Fomin V, Regunath K, Zhou J, Zhou W, Silwal Pandit L, et al. Mutant p53 cooperates with the SWI/SNF chromatin remodeling complex to regulate VEGFR2 in breast cancer cells. Genes Dev. 2015;29:1298-315 pubmed publisher
Planeix F, Siraj M, Bidard F, Robin B, Pichon C, Sastre Garau X, et al. Endothelial follicle-stimulating hormone receptor expression in invasive breast cancer and vascular remodeling at tumor periphery. J Exp Clin Cancer Res. 2015;34:12 pubmed publisher
de Laplanche E, Boudria A, Dacheux E, Vincent A, Gadot N, Assade F, et al. Low glucose microenvironment of normal kidney cells stabilizes a subset of messengers involved in angiogenesis. Physiol Rep. 2015;3: pubmed publisher
Xu W, Li B, Lam A, Tsao S, Law S, Chan K, et al. Targeting VEGFR1- and VEGFR2-expressing non-tumor cells is essential for esophageal cancer therapy. Oncotarget. 2015;6:1790-805 pubmed
Razanadrakoto L, Cormier F, Laurienté V, Dondi E, Gardano L, Katzav S, et al. Mutation of Vav1 adaptor region reveals a new oncogenic activation. Oncotarget. 2015;6:2524-37 pubmed
Adamczak J, Schneider G, Nelles M, Que I, Suidgeest E, van der Weerd L, et al. In vivo bioluminescence imaging of vascular remodeling after stroke. Front Cell Neurosci. 2014;8:274 pubmed publisher
Kere M, Siriboon C, Liao J, Lo N, Chiang H, Fan Y, et al. Vascular endothelial growth factor A improves quality of matured porcine oocytes and developing parthenotes. Domest Anim Endocrinol. 2014;49:60-9 pubmed publisher
Jansson S, Bendahl P, Grabau D, Falck A, Fernö M, Aaltonen K, et al. The three receptor tyrosine kinases c-KIT, VEGFR2 and PDGFR?, closely spaced at 4q12, show increased protein expression in triple-negative breast cancer. PLoS ONE. 2014;9:e102176 pubmed publisher
Gnavi S, di Blasio L, Tonda Turo C, Mancardi A, Primo L, Ciardelli G, et al. Gelatin-based hydrogel for vascular endothelial growth factor release in peripheral nerve tissue engineering. J Tissue Eng Regen Med. 2017;11:459-470 pubmed publisher
Del Puerto Nevado L, Rojo F, Zazo S, Carames C, Rubio G, Vega R, et al. Active angiogenesis in metastatic renal cell carcinoma predicts clinical benefit to sunitinib-based therapy. Br J Cancer. 2014;110:2700-7 pubmed publisher
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product information
SKU :
2479L
Product-Name :
VEGF Receptor 2 (55B11) Rabbit mAb
Size :
300 ul
Price-(USD) :
574 USD
Species-x-Reactivity :
H, M
Applications :
Immunofluorescence (Immunocytochemistry)
Product-Category :
RTK
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
210, 230
Host :
Rabbit
Target :
VEGFR2
Primary-Protein :
VEGFR-2
Alt-Names :
CD309,FLK-1,FLK1,Fetal liver kinase 1,KDR,Kinase insert domain receptor,Protein-tyrosine kinase receptor flk-1,VEGFR,VEGFR-2,VEGFR2,VGFR2,Vascular endothelial growth factor receptor 2,fetal liver kinase-1,kinase insert domain receptor (a type III receptor tyrosine kinase),soluble VEGFR2,tyrosine kinase growth factor receptor
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.