product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
eIF4G (C45A4) Rabbit mAb
catalog :
2469
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
C45A4
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry
citations: 9
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 3b
Lingel H, Wissing J, Arra A, Schanze D, Lienenklaus S, Klawonn F, et al. CTLA-4-mediated posttranslational modifications direct cytotoxic T-lymphocyte differentiation. Cell Death Differ. 2017;24:1739-1749 pubmed publisher
  • western blot; mouse; loading ...; fig s1a
Tahmasebi S, Jafarnejad S, Tam I, Gonatopoulos Pournatzis T, Matta Camacho E, Tsukumo Y, et al. Control of embryonic stem cell self-renewal and differentiation via coordinated alternative splicing and translation of YY2. Proc Natl Acad Sci U S A. 2016;113:12360-12367 pubmed
  • western blot; mouse; loading ...; fig s3d
Tsai S, Rodriguez A, Dastidar S, Del Greco E, Carr K, Sitzmann J, et al. Increased 4E-BP1 Expression Protects against Diet-Induced Obesity and Insulin Resistance in Male Mice. Cell Rep. 2016;16:1903-14 pubmed publisher
  • western blot; human; fig 4
Lyabin D, Ovchinnikov L. Selective regulation of YB-1 mRNA translation by the mTOR signaling pathway is not mediated by 4E-binding protein. Sci Rep. 2016;6:22502 pubmed publisher
Fonseca B, Zakaria C, Jia J, Graber T, Svitkin Y, Tahmasebi S, et al. La-related Protein 1 (LARP1) Represses Terminal Oligopyrimidine (TOP) mRNA Translation Downstream of mTOR Complex 1 (mTORC1). J Biol Chem. 2015;290:15996-6020 pubmed publisher
Knopp K, Ngo T, Gershon P, Buchmeier M. Single nucleoprotein residue modulates arenavirus replication complex formation. MBio. 2015;6:e00524-15 pubmed publisher
Wang N, Feng Y, Tan H, Cheung F, Hong M, Lao L, et al. Inhibition of eukaryotic elongation factor-2 confers to tumor suppression by a herbal formulation Huanglian-Jiedu decoction in human hepatocellular carcinoma. J Ethnopharmacol. 2015;164:309-18 pubmed publisher
Tahiri Alaoui A, Zhao Y, Sadigh Y, Popplestone J, Kgosana L, Smith L, et al. Poly(A) binding protein 1 enhances cap-independent translation initiation of neurovirulence factor from avian herpesvirus. PLoS ONE. 2014;9:e114466 pubmed publisher
Dobson T, Chen J, Krushel L. Dysregulating IRES-dependent translation contributes to overexpression of oncogenic Aurora A Kinase. Mol Cancer Res. 2013;11:887-900 pubmed publisher
product information
SKU :
2469S
Product-Name :
eIF4G (C45A4) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Flow cytometry
Product-Category :
Translational Control
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
220
Host :
Rabbit
Target :
eIF4G
Primary-Protein :
eIF4G
Alt-Names :
DKFZp686A1451,EIF4-gamma,EIF4F,EIF4G,EIF4G1,EIF4GI,Eukaryotic translation initiation factor 4 gamma 1,IF4G1,eIF-4-gamma 1,eIF-4G 1,eIF-4G1,eukaryotic translation initiation factor 4 gamma, 1,p220
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.