product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
PTCH1 (C53A3) Rabbit mAb
catalog :
2468
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
C53A3
reactivity :
human
application :
western blot, immunoprecipitation
more info or order :
Cell Signaling Technology product webpage
citations: 6
Published Application/Species/Sample/DilutionReference
  • immunoprecipitation; human; loading ...; fig 1f
Li N, Truong S, Nouri M, Moore J, Al Nakouzi N, Lubik A, et al. Non-canonical activation of hedgehog in prostate cancer cells mediated by the interaction of transcriptionally active androgen receptor proteins with Gli3. Oncogene. 2018;37:2313-2325 pubmed publisher
  • western blot; human; loading ...; fig 5
Galoian K, Luo S, Qureshi A, Patel P, Price R, Morse A, et al. Effect of cytostatic proline rich polypeptide-1 on tumor suppressors of inflammation pathway signaling in chondrosarcoma. Mol Clin Oncol. 2016;5:618-624 pubmed
  • western blot; human; 1:1000; fig 6
Wang H, Ning Z, Li Y, Zhu X, Meng Z. Bufalin suppresses cancer stem-like cells in gemcitabine-resistant pancreatic cancer cells via Hedgehog signaling. Mol Med Rep. 2016;14:1907-14 pubmed publisher
  • western blot; human; 1:1000; fig 1
Fan C, Wang Y, Liu Z, Sun Y, Wang X, Wei G, et al. Metformin exerts anticancer effects through the inhibition of the Sonic hedgehog signaling pathway in breast cancer. Int J Mol Med. 2015;36:204-14 pubmed publisher
Chen X, Chinchilla P, Fombonne J, Ho L, Guix C, Keen J, et al. Patched-1 proapoptotic activity is downregulated by modification of K1413 by the E3 ubiquitin-protein ligase Itchy homolog. Mol Cell Biol. 2014;34:3855-66 pubmed publisher
Shimada Y, Katsube K, Kabasawa Y, Morita K, Omura K, Yamaguchi A, et al. Integrated genotypic analysis of hedgehog-related genes identifies subgroups of keratocystic odontogenic tumor with distinct clinicopathological features. PLoS ONE. 2013;8:e70995 pubmed publisher
product information
SKU :
2468S
Product-Name :
PTCH1 (C53A3) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H
Applications :
Immunoprecipitation
Product-Category :
Developmental Biology
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
180-210
Host :
Rabbit
Target :
Ptch1
Primary-Protein :
PTCH1
Alt-Names :
BCNS,FLJ26746,FLJ42602,HPE7,NBCCS,PTC,PTC1,PTCH,PTCH protein +12b,PTCH protein +4 ,PTCH protein -10,PTCH1,PTCH11,Protein patched homolog 1,patched homolog 1 (Drosophila)
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.