product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Cdc42 (11A11) Rabbit mAb
catalog :
2466S
quantity :
100 ul
price :
235 USD
clonality :
monoclonal
host :
rabbit
reactivity :
human, mouse, rat, cow
application :
western blot
citations: 6
Published Application/Species/DilutionReference
  • western blot (knockdown validation); human; fig s9
Westcott J, Prechtl A, Maine E, Dang T, Esparza M, Sun H, et al. An epigenetically distinct breast cancer cell subpopulation promotes collective invasion. J Clin Invest. 2015;125:1927-43 pubmed publisher
  • western blot; human; 1:5000; fig 3
Bruurs L, Donker L, Zwakenberg S, Zwartkruis F, Begthel H, Knisely A, et al. ATP8B1-mediated spatial organization of Cdc42 signaling maintains singularity during enterocyte polarization. J Cell Biol. 2015;210:1055-63 pubmed publisher
Rohani M, PILCHER B, Chen P, Parks W. Cdc42 inhibits ERK-mediated collagenase-1 (MMP-1) expression in collagen-activated human keratinocytes. J Invest Dermatol. 2014;134:1230-7 pubmed publisher
Humphreys K, McKinnon R, Michael M. miR-18a inhibits CDC42 and plays a tumour suppressor role in colorectal cancer cells. PLoS ONE. 2014;9:e112288 pubmed publisher
Jung J, Oh J, Lee D, Lee S, Chung J. Blood type B antigen modulates cell migration through regulating cdc42 expression and activity in HaCaT cells. J Cell Physiol. 2013;228:2243-51 pubmed publisher
Tang X, Jin R, Qu G, Wang X, Li Z, Yuan Z, et al. GPR116, an adhesion G-protein-coupled receptor, promotes breast cancer metastasis via the Gαq-p63RhoGEF-Rho GTPase pathway. Cancer Res. 2013;73:6206-18 pubmed publisher
product information
SKU :
2466S
Product-Name :
Cdc42 (11A11) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, B, (X)
Applications :
Western blot
Product-Category :
Cytoskeletal Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
21
Host :
Rabbit
Target :
Cdc42
Primary-Protein :
Cdc42 iso1
Alt-Names :
CDC42,CDC42Hs,Cell division control protein 42 homolog,G25K,G25K GTP-binding protein,GTP-binding protein, 25kD,cell division cycle 42 (GTP binding protein, 25kDa),dJ224A6.1.1 (cell division cycle 42 (GTP-binding protein, 25kD)),dJ224A6.1.2 (cell division cycle 42 (GTP-binding protein, 25kD)),growth-regulating protein,small GTP binding protein CDC42
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.