product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Rac1/2/3 Antibody
catalog :
2465
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, cow
application :
western blot, flow cytometry
citations: 15
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 2b
Sahu U, Choudhury A, Parvez S, Biswas S, Kar S. Induction of intestinal stemness and tumorigenicity by aberrant internalization of commensal non-pathogenic E. coli. Cell Death Dis. 2017;8:e2667 pubmed publisher
  • western blot; human; fig 4
Bianchi Smiraglia A, Bagati A, Fink E, Moparthy S, Wawrzyniak J, Marvin E, et al. Microphthalmia-associated transcription factor suppresses invasion by reducing intracellular GTP pools. Oncogene. 2017;36:84-96 pubmed publisher
  • western blot; human; loading ...; fig s4b
Liu Z, Chu S, Yao S, Li Y, Fan S, Sun X, et al. CD74 interacts with CD44 and enhances tumorigenesis and metastasis via RHOA-mediated cofilin phosphorylation in human breast cancer cells. Oncotarget. 2016;7:68303-68313 pubmed publisher
  • western blot; human; 1:300; loading ...; fig 2
Efazat G, Novak M, Kaminskyy V, De Petris L, Kanter L, Juntti T, et al. Ephrin B3 interacts with multiple EphA receptors and drives migration and invasion in non-small cell lung cancer. Oncotarget. 2016;7:60332-60347 pubmed publisher
  • western blot; mouse; 1:1000; fig 5
Reinhard J, Kriz A, Galic M, Angliker N, Rajalu M, Vogt K, et al. The calcium sensor Copine-6 regulates spine structural plasticity and learning and memory. Nat Commun. 2016;7:11613 pubmed publisher
Agabiti S, Li J, Wiemer A. Geranylgeranyl diphosphate synthase inhibition induces apoptosis that is dependent upon GGPP depletion, ERK phosphorylation and caspase activation. Cell Death Dis. 2017;8:e2678 pubmed publisher
Kashtan C. Alport syndrome: facts and opinions. F1000Res. 2017;6:50 pubmed publisher
Wang Y, Yan F, Ye Q, Wu X, Jiang F. PTP1B inhibitor promotes endothelial cell motility by activating the DOCK180/Rac1 pathway. Sci Rep. 2016;6:24111 pubmed publisher
Pasquier J, Abu Kaoud N, Abdesselem H, Madani A, Hoarau Véchot J, Thawadi H, et al. SDF-1alpha concentration dependent modulation of RhoA and Rac1 modifies breast cancer and stromal cells interaction. BMC Cancer. 2015;15:569 pubmed publisher
Candelaria N, Addanki S, Zheng J, Nguyen Vu T, Karaboga H, Dey P, et al. Antiproliferative effects and mechanisms of liver X receptor ligands in pancreatic ductal adenocarcinoma cells. PLoS ONE. 2014;9:e106289 pubmed publisher
Berger A, Chen M, Morotti A, Janas J, Niki M, Bronson R, et al. DOK2 inhibits EGFR-mutated lung adenocarcinoma. PLoS ONE. 2013;8:e79526 pubmed publisher
Goggs R, Savage J, Mellor H, Poole A. The small GTPase Rif is dispensable for platelet filopodia generation in mice. PLoS ONE. 2013;8:e54663 pubmed publisher
Chen Z, Lessey E, Berginski M, Cao L, Li J, Trepat X, et al. Gleevec, an Abl family inhibitor, produces a profound change in cell shape and migration. PLoS ONE. 2013;8:e52233 pubmed publisher
Toullec A, Gerald D, Despouy G, Bourachot B, Cardon M, Lefort S, et al. Oxidative stress promotes myofibroblast differentiation and tumour spreading. EMBO Mol Med. 2010;2:211-30 pubmed publisher
Mythreye K, Blobe G. The type III TGF-beta receptor regulates epithelial and cancer cell migration through beta-arrestin2-mediated activation of Cdc42. Proc Natl Acad Sci U S A. 2009;106:8221-6 pubmed publisher
product information
SKU :
2465P
Product-Name :
Rac1/2/3 Antibody
Size :
40 ul
Price-(USD) :
123 USD
Species-x-Reactivity :
H, M, R, Mk, B, (X)
Applications :
Flow cytometry
Product-Category :
Cytoskeletal Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
21
Host :
Rabbit
Target :
Rac1/Rac2/Rac3
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.