product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Cdc42 Antibody
catalog :
2462
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dog, cow
application :
western blot, immunocytochemistry
more info or order :
Cell Signaling Technology product webpage
citations: 20
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 1i
Li L, Baxter S, Gu N, Ji M, Zhan X. Missing-in-metastasis protein downregulates CXCR4 by promoting ubiquitylation and interaction with small Rab GTPases. J Cell Sci. 2017;130:1475-1485 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig s3i
Rafiq N, Lieu Z, Jiang T, Yu C, Matsudaira P, Jones G, et al. Podosome assembly is controlled by the GTPase ARF1 and its nucleotide exchange factor ARNO. J Cell Biol. 2017;216:181-197 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 4d
  • western blot; human; loading ...; fig 4c
Xiao B, Chen D, Luo S, Hao W, Jing F, Liu T, et al. Extracellular translationally controlled tumor protein promotes colorectal cancer invasion and metastasis through Cdc42/JNK/ MMP9 signaling. Oncotarget. 2016;7:50057-50073 pubmed publisher
  • western blot; human; fig 2
  • western blot; rat; fig 4
Yu D, Makkar G, Strickland D, Blanpied T, Stumpo D, Blackshear P, et al. Myristoylated Alanine-Rich Protein Kinase Substrate (MARCKS) Regulates Small GTPase Rac1 and Cdc42 Activity and Is a Critical Mediator of Vascular Smooth Muscle Cell Migration in Intimal Hyperplasia Formation. J Am Heart Assoc. 2015;4:e002255 pubmed publisher
  • western blot; human; fig 1
Gramolelli S, Weidner Glunde M, Abere B, Viejo Borbolla A, Bala K, Rückert J, et al. Inhibiting the Recruitment of PLCγ1 to Kaposi's Sarcoma Herpesvirus K15 Protein Reduces the Invasiveness and Angiogenesis of Infected Endothelial Cells. PLoS Pathog. 2015;11:e1005105 pubmed publisher
Wu X, Yang Y, Li W, Cheng Y, Li X, Huang C, et al. Telomerase reverse transcriptase acts in a feedback loop with NF-κB pathway to regulate macrophage polarization in alcoholic liver disease. Sci Rep. 2016;6:18685 pubmed publisher
Yang H, Collins S, Meyer T. Locally excitable Cdc42 signals steer cells during chemotaxis. Nat Cell Biol. 2016;18:191-201 pubmed publisher
Park S, Yang J, Schmider A, Soberman R, Hsu V. Coordinated regulation of bidirectional COPI transport at the Golgi by CDC42. Nature. 2015;521:529-32 pubmed publisher
Howell M, Brickner H, Delorme Walker V, Choi J, Saffin J, Miller D, et al. WISp39 binds phosphorylated Coronin 1B to regulate Arp2/3 localization and Cofilin-dependent motility. J Cell Biol. 2015;208:961-74 pubmed publisher
Hayasaka H, Kobayashi D, Yoshimura H, Nakayama E, Shioda T, Miyasaka M. The HIV-1 Gp120/CXCR4 axis promotes CCR7 ligand-dependent CD4 T cell migration: CCR7 homo- and CCR7/CXCR4 hetero-oligomer formation as a possible mechanism for up-regulation of functional CCR7. PLoS ONE. 2015;10:e0117454 pubmed publisher
Berth S, Caicedo H, Sarma T, Morfini G, Brady S. Internalization and axonal transport of the HIV glycoprotein gp120. ASN Neuro. 2015;7: pubmed publisher
Hoe S, Tan L, Jamal J, Peh S, Ng C, Zhang W, et al. Evaluation of stem-like side population cells in a recurrent nasopharyngeal carcinoma cell line. Cancer Cell Int. 2014;14:101 pubmed publisher
Rainero E, Cianflone C, Porporato P, Chianale F, Malacarne V, Bettio V, et al. The diacylglycerol kinase ?/atypical PKC/?1 integrin pathway in SDF-1? mammary carcinoma invasiveness. PLoS ONE. 2014;9:e97144 pubmed publisher
Oddsson A, Kristinsson S, Helgason H, Gudbjartsson D, Masson G, Sigurdsson A, et al. The germline sequence variant rs2736100_C in TERT associates with myeloproliferative neoplasms. Leukemia. 2014;28:1371-4 pubmed publisher
Veland I, Montjean R, Eley L, Pedersen L, Schwab A, Goodship J, et al. Inversin/Nephrocystin-2 is required for fibroblast polarity and directional cell migration. PLoS ONE. 2013;8:e60193 pubmed publisher
Goggs R, Savage J, Mellor H, Poole A. The small GTPase Rif is dispensable for platelet filopodia generation in mice. PLoS ONE. 2013;8:e54663 pubmed publisher
Chen Z, Lessey E, Berginski M, Cao L, Li J, Trepat X, et al. Gleevec, an Abl family inhibitor, produces a profound change in cell shape and migration. PLoS ONE. 2013;8:e52233 pubmed publisher
Shikatani E, Trifonova A, Mandel E, Liu S, Roudier E, Krylova A, et al. Inhibition of proliferation, migration and proteolysis contribute to corticosterone-mediated inhibition of angiogenesis. PLoS ONE. 2012;7:e46625 pubmed publisher
Mythreye K, Blobe G. The type III TGF-beta receptor regulates epithelial and cancer cell migration through beta-arrestin2-mediated activation of Cdc42. Proc Natl Acad Sci U S A. 2009;106:8221-6 pubmed publisher
Monypenny J, Zicha D, Higashida C, Oceguera Yanez F, Narumiya S, Watanabe N. Cdc42 and Rac family GTPases regulate mode and speed but not direction of primary fibroblast migration during platelet-derived growth factor-dependent chemotaxis. Mol Cell Biol. 2009;29:2730-47 pubmed publisher
product information
SKU :
2462S
Product-Name :
Cdc42 Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk, B, (C, X, Z, Dg)
Applications :
Western blot
Product-Category :
Cytoskeletal Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
21
Host :
Rabbit
Target :
Cdc42
Primary-Protein :
Cdc42 iso1
Alt-Names :
CDC42,CDC42Hs,Cell division control protein 42 homolog,G25K,G25K GTP-binding protein,GTP-binding protein, 25kD,cell division cycle 42 (GTP binding protein, 25kDa),dJ224A6.1.1 (cell division cycle 42 (GTP-binding protein, 25kD)),dJ224A6.1.2 (cell division cycle 42 (GTP-binding protein, 25kD)),growth-regulating protein,small GTP binding protein CDC42
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.