product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
APP Antibody
catalog :
2452
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry
more info or order :
Cell Signaling Technology product webpage
citations: 6
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 3e
Pan R, Ma J, Kong X, Wang X, Li S, Qi X, et al. Sodium rutin ameliorates Alzheimer's disease-like pathology by enhancing microglial amyloid-β clearance. Sci Adv. 2019;5:eaau6328 pubmed publisher
  • western blot; mouse; loading ...; fig 6b
Huang M, Qi W, Fang S, Jiang P, Yang C, Mo Y, et al. Pigment Epithelium-Derived Factor Plays a Role in Alzheimer's Disease by Negatively Regulating Aβ42. Neurotherapeutics. 2018;15:728-741 pubmed publisher
  • western blot; human; 1:1000; fig 4
Kim H, Lee K, Kim A, Choi M, Choi K, Kang M, et al. A chemical with proven clinical safety rescues Down-syndrome-related phenotypes in through DYRK1A inhibition. Dis Model Mech. 2016;9:839-48 pubmed publisher
  • western blot; mouse; fig 1
Stroh M, Winter M, Swerdlow R, McCarson K, Zhu H. Loss of NCB5OR in the cerebellum disturbs iron pathways, potentiates behavioral abnormalities, and exacerbates harmaline-induced tremor in mice. Metab Brain Dis. 2016;31:951-64 pubmed publisher
  • western blot; mouse; 1:1000; tbl 1
Guillot F, Kemppainen S, Lavasseur G, Miettinen P, Laroche S, Tanila H, et al. Brain-Specific Basal and Novelty-Induced Alternations in PI3K-Akt and MAPK/ERK Signaling in a Middle-Aged AβPP/PS1 Mouse Model of Alzheimer's Disease. J Alzheimers Dis. 2016;51:1157-73 pubmed publisher
Liu H, Huang Y, Liu J, Huang Q. Transcription factor?microRNA synergistic regulatory network revealing the mechanism of polycystic ovary syndrome. Mol Med Rep. 2016;13:3920-8 pubmed publisher
product information
SKU :
2452S
Product-Name :
APP Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Immunofluorescence (Immunocytochemistry)
Product-Category :
Neuroscience
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
100 to 140
Host :
Rabbit
Target :
APP
Primary-Protein :
APP
Alt-Names :
A4,AAA,ABETA,ABPP,AD1,AICD-50,AICD-57,AICD-59,AID(50),AID(57),AID(59),APP,APPI,Alzheimer disease amyloid protein,Amyloid beta A4 protein,Amyloid intracellular domain 50,Amyloid intracellular domain 57,Amyloid intracellular domain 59,Beta-APP40,Beta-APP42,Beta-amyloid protein 40,Beta-amyloid protein 42,C31,C80,C83,C99,CTFgamma,CVAP,Cerebral vascular amyloid peptide,Gamma-CTF(50),Gamma-CTF(57),Gamma-CTF(59),Gamma-secretase C-terminal fragment 50,Gamma-secretase C-terminal fragment 57,Gamma-secretase C-terminal fragment 59,N-APP,P3(40),P3(42),PN-II,PN2,PreA4,Protease nexin-II,S-APP-alpha,S-APP-beta,Soluble APP-alpha,Soluble APP-beta,amyloid beta (A4) precursor protein,beta-amyloid peptide,peptidase nexin-II
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.