product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
ATGL (30A4) Rabbit mAb
catalog :
2439
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
30A4
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
Cell Signaling Technology product webpage
citations: 22
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 2i
Liu Y, Cong P, Zhang T, Wang R, Wang X, Liu J, et al. Plasmalogen attenuates the development of hepatic steatosis and cognitive deficit through mechanism involving p75NTR inhibition. Redox Biol. 2021;43:102002 pubmed publisher
  • western blot; mouse; loading ...; fig 3e
Zhang G, Li R, Li W, Yang S, Sun Q, Yin H, et al. Toll-like receptor 3 ablation prevented high-fat diet-induced obesity and metabolic disorder. J Nutr Biochem. 2021;95:108761 pubmed publisher
  • western blot; mouse; loading ...; fig 6h
You L, Wang Y, Gao Y, Wang X, Cui X, Zhang Y, et al. The role of microRNA-23b-5p in regulating brown adipogenesis and thermogenic program. Endocr Connect. 2020;9:457-470 pubmed publisher
  • western blot; mouse; loading ...; fig 6a
  • immunohistochemistry - paraffin section; human; loading ...; fig 8i
Li X, Wu Y, Zhao J, Wang H, Tan J, Yang M, et al. Distinct cardiac energy metabolism and oxidative stress adaptations between obese and non-obese type 2 diabetes mellitus. Theranostics. 2020;10:2675-2695 pubmed publisher
  • western blot; mouse; loading ...; fig s4a
Yang C, Wang X, Wang J, Wang X, Chen W, Lu N, et al. Rewiring Neuronal Glycerolipid Metabolism Determines the Extent of Axon Regeneration. Neuron. 2020;105:276-292.e5 pubmed publisher
  • immunoprecipitation; human; fig s5b
  • immunocytochemistry; human; fig s5a
Peng Y, Miao H, Wu S, Yang W, Zhang Y, Xie G, et al. ABHD5 interacts with BECN1 to regulate autophagy and tumorigenesis of colon cancer independent of PNPLA2. Autophagy. 2016;12:2167-2182 pubmed
  • western blot; mouse; 1:1000; fig 1
Smagris E, Gilyard S, BasuRay S, Cohen J, Hobbs H. Inactivation of Tm6sf2, a Gene Defective in Fatty Liver Disease, Impairs Lipidation but Not Secretion of Very Low Density Lipoproteins. J Biol Chem. 2016;291:10659-76 pubmed publisher
  • western blot; mouse
Iglesias J, Lamontagne J, Erb H, Gezzar S, Zhao S, Joly E, et al. Simplified assays of lipolysis enzymes for drug discovery and specificity assessment of known inhibitors. J Lipid Res. 2016;57:131-41 pubmed publisher
  • western blot; mouse; 1:1000; fig 6d
Abreu Vieira G, Fischer A, Mattsson C, de Jong J, Shabalina I, Ryden M, et al. Cidea improves the metabolic profile through expansion of adipose tissue. Nat Commun. 2015;6:7433 pubmed publisher
  • immunocytochemistry; mouse; 1:100; fig 6
Kaushik S, Cuervo A. Degradation of lipid droplet-associated proteins by chaperone-mediated autophagy facilitates lipolysis. Nat Cell Biol. 2015;17:759-70 pubmed publisher
  • western blot; mouse; 1:1000; fig 7c
Seillier M, Pouyet L, N Guessan P, Nollet M, Capo F, Guillaumond F, et al. Defects in mitophagy promote redox-driven metabolic syndrome in the absence of TP53INP1. EMBO Mol Med. 2015;7:802-18 pubmed publisher
  • western blot; rat; 1:700
Turnbull P, Ramos S, Macpherson R, Roy B, Peters S. Characterization of lipolytic inhibitor G(0)/G(1) switch gene-2 protein (G0S2) expression in male Sprague-Dawley rat skeletal muscle compared to relative content of adipose triglyceride lipase (ATGL) and comparitive gene identification-58 (CGI-58). PLoS ONE. 2015;10:e0120136 pubmed publisher
  • western blot; mouse; fig 4
Mo X, Yang C, Wang X, Burkhardt B, Li Y, Xia H, et al. F3MB(PANDER) decreases mice hepatic triglyceride and is associated with decreased DGAT1 expression. PLoS ONE. 2015;10:e0117156 pubmed publisher
  • western blot; mouse; 1:1000; fig 1
Zhou L, Park S, Xu L, Xia X, Ye J, Su L, et al. Insulin resistance and white adipose tissue inflammation are uncoupled in energetically challenged Fsp27-deficient mice. Nat Commun. 2015;6:5949 pubmed publisher
  • western blot; rat; 1:1,000
Macpherson R, Castelli L, Miotto P, Frendo Cumbo S, Milburn A, Roy B, et al. A maternal high fat diet has long-lasting effects on skeletal muscle lipid and PLIN protein content in rat offspring at young adulthood. Lipids. 2015;50:205-17 pubmed publisher
  • western blot; mouse; 1:1000
Jha P, Knopf A, Koefeler H, Mueller M, Lackner C, Hoefler G, et al. Role of adipose tissue in methionine-choline-deficient model of non-alcoholic steatohepatitis (NASH). Biochim Biophys Acta. 2014;1842:959-70 pubmed publisher
  • immunocytochemistry; mouse
Mottillo E, Paul G, Moore H, Granneman J. Use of fluorescence microscopy to probe intracellular lipolysis. Methods Enzymol. 2014;538:263-78 pubmed publisher
  • immunoprecipitation; mouse
  • western blot; mouse
Macpherson R, Vandenboom R, Roy B, Peters S. Skeletal muscle PLIN3 and PLIN5 are serine phosphorylated at rest and following lipolysis during adrenergic or contractile stimulation. Physiol Rep. 2013;1:e00084 pubmed publisher
Lee P, Tang Y, Li H, Guertin D. Raptor/mTORC1 loss in adipocytes causes progressive lipodystrophy and fatty liver disease. Mol Metab. 2016;5:422-432 pubmed publisher
Alfaradhi M, Fernandez Twinn D, Martin Gronert M, Musial B, Fowden A, Ozanne S. Oxidative stress and altered lipid homeostasis in the programming of offspring fatty liver by maternal obesity. Am J Physiol Regul Integr Comp Physiol. 2014;307:R26-34 pubmed publisher
Sitnick M, Basantani M, Cai L, Schoiswohl G, Yazbeck C, Distefano G, et al. Skeletal muscle triacylglycerol hydrolysis does not influence metabolic complications of obesity. Diabetes. 2013;62:3350-61 pubmed publisher
Wang H, Bell M, Sreenivasan U, Sreenevasan U, Hu H, Liu J, et al. Unique regulation of adipose triglyceride lipase (ATGL) by perilipin 5, a lipid droplet-associated protein. J Biol Chem. 2011;286:15707-15 pubmed publisher
product information
SKU :
2439S
Product-Name :
ATGL (30A4) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
M
Applications :
Immunofluorescence (Immunocytochemistry)
Product-Category :
Metabolism
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
54
Host :
Rabbit
Target :
ATGL
Primary-Protein :
PNPLA2
Alt-Names :
1110001C14Rik,ATGL,Adipose triglyceride lipase,Calcium-independent phospholipase A2,DKFZp667M109,Desnutrin,FP17548,IPLA2-zeta,PEDF-R,PLPL2,PNPLA2,Patatin-like phospholipase domain-containing protein 2,Pigment epithelium-derived factor,TTS-2.2,TTS2,TTS2.2,Transport-secretion protein 2,patatin-like phospholipase domain containing 2,transport-secretion protein 2.2,triglyceride hydrolase
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.