product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-Shc (Tyr239/240) Antibody
catalog :
2434
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
antigen modification :
phosphorylated
reactivity :
human, mouse, rat, cow
application :
western blot
citations: 7
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 4a
Baumann C, Ullrich A, Torka R. GAS6-expressing and self-sustaining cancer cells in 3D spheroids activate the PDK-RSK-mTOR pathway for survival and drug resistance. Mol Oncol. 2017;11:1430-1447 pubmed publisher
  • western blot; mouse; 1:500; fig 7e
Cai W, Sakaguchi M, Kleinridders A, Gonzalez Del Pino G, Dreyfuss J, O Neill B, et al. Domain-dependent effects of insulin and IGF-1 receptors on signalling and gene expression. Nat Commun. 2017;8:14892 pubmed publisher
  • western blot; human; 1:1000; fig 6
Barrow McGee R, Kishi N, Joffre C, Ménard L, Hervieu A, Bakhouche B, et al. Beta 1-integrin-c-Met cooperation reveals an inside-in survival signalling on autophagy-related endomembranes. Nat Commun. 2016;7:11942 pubmed publisher
  • western blot; human; fig 4
Richter E, Harms M, Ventz K, Gierok P, Chilukoti R, Hildebrandt J, et al. A multi-omics approach identifies key hubs associated with cell type-specific responses of airway epithelial cells to staphylococcal alpha-toxin. PLoS ONE. 2015;10:e0122089 pubmed publisher
  • western blot; cow; 1:1000
Ahmed N, Iu J, Brown C, Taylor D, Kandel R. Serum- and growth-factor-free three-dimensional culture system supports cartilage tissue formation by promoting collagen synthesis via Sox9-Col2a1 interaction. Tissue Eng Part A. 2014;20:2224-33 pubmed publisher
Lazaridis I, Charalampopoulos I, Alexaki V, Avlonitis N, Pediaditakis I, Efstathopoulos P, et al. Neurosteroid dehydroepiandrosterone interacts with nerve growth factor (NGF) receptors, preventing neuronal apoptosis. PLoS Biol. 2011;9:e1001051 pubmed publisher
Krall J, Beyer E, MacBeath G. High- and low-affinity epidermal growth factor receptor-ligand interactions activate distinct signaling pathways. PLoS ONE. 2011;6:e15945 pubmed publisher
product information
SKU :
2434S
Product-Name :
Phospho-Shc (Tyr239/240) Antibody
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H, M, R
Applications :
Western blot
Product-Category :
MAP Kinase Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
50, 55, 70
Host :
Rabbit
Target :
Shc1 (Tyr349/Tyr350) phosphate
Primary-Protein :
Shc1
Alt-Names :
FLJ26504,SH2 domain protein C1,SHC,SHC (Src homology 2 domain containing) transforming protein 1,SHC (Src homology 2 domain-containing) transforming protein 1,SHC-transforming protein 1,SHC-transforming protein 3,SHC-transforming protein A,SHC1,SHCA,Src homology 2 domain-containing-transforming protein C1
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.