product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-Shc (Tyr317) Antibody
catalog :
2431
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
antigen modification :
phosphorylated
reactivity :
human, mouse, rat
application :
western blot, reverse phase protein lysate microarray, other
more info or order :
Cell Signaling Technology product webpage
citations: 6
Published Application/Species/Sample/DilutionReference
  • western blot; rat; loading ...; fig 1b
Lundby A, Franciosa G, Emdal K, Refsgaard J, Gnosa S, Bekker Jensen D, et al. Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites. Cell. 2019;179:543-560.e26 pubmed publisher
  • other; human; loading ...; fig 4c
Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  • reverse phase protein lysate microarray; human; loading ...; fig st6
Cherniack A, Shen H, Walter V, Stewart C, Murray B, Bowlby R, et al. Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell. 2017;31:411-423 pubmed publisher
  • western blot; human; fig 2s2
Jadwin J, Oh D, Curran T, Ogiue Ikeda M, Jia L, White F, et al. Time-resolved multimodal analysis of Src Homology 2 (SH2) domain binding in signaling by receptor tyrosine kinases. elife. 2016;5:e11835 pubmed publisher
  • western blot; human
Fan C, Chen C, Chen K, Shen C, Kuo Y, Chen Y, et al. Blockade of phospholipid scramblase 1 with its N-terminal domain antibody reduces tumorigenesis of colorectal carcinomas in vitro and in vivo. J Transl Med. 2012;10:254 pubmed publisher
Lin S, Yu L, Yang J, Liu Z, Karia B, Bishop A, et al. Mutant p53 disrupts role of ShcA protein in balancing Smad protein-dependent and -independent signaling activity of transforming growth factor-? (TGF-?). J Biol Chem. 2011;286:44023-34 pubmed publisher
product information
SKU :
2431S
Product-Name :
Phospho-Shc (Tyr317) Antibody
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H, M
Applications :
Western blot
Product-Category :
MAP Kinase Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
50, 55, 70
Host :
Rabbit
Target :
Shc1 (Tyr427) phosphate
Primary-Protein :
Shc1
Alt-Names :
FLJ26504,SH2 domain protein C1,SHC,SHC (Src homology 2 domain containing) transforming protein 1,SHC (Src homology 2 domain-containing) transforming protein 1,SHC-transforming protein 1,SHC-transforming protein 3,SHC-transforming protein A,SHC1,SHCA,Src homology 2 domain-containing-transforming protein C1
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.